Hematology Exam 1 UAMS UPDATED
ACTUAL Questions and CORRECT
Answers
Anticoagulants - CORRECT ANSWER - EDTA (most common), heparin, sodium citrate
Types of Normal Blood Cells Found in Peripheral Blood - CORRECT ANSWER - • Red
Blood Cells
Platelets
White Blood Cells
Lymphocyte
Monocyte
(Granulocytes)
Eosinophil
Basophil (baso)
Segmented neutrophil
• Band neutrophil
"cyte" - CORRECT ANSWER - cell
Intramedullary hemolysis - CORRECT ANSWER - within bone marrow cell break-up
Extramedullary hemolysis - CORRECT ANSWER - outside bone marrow cell lysis
- Cell destruction outside the bone marrow - CORRECT ANSWER - Extramedullary
hemolysis
Erythroid hyperplasia - CORRECT ANSWER - increased red cell formation
,Lymphopenia - CORRECT ANSWER - decreased number of lymphs
Eosinophilia - CORRECT ANSWER - increased number of eos
Polycythemia - CORRECT ANSWER - All cells in the blood are increased many cells
increased
Intravascular Hemolysis - CORRECT ANSWER - inside vessel breakdown of RBCS
CBC includes - CORRECT ANSWER - WBC, RBC, platelet count, hemoglobin (hgb),
hematocrit (hct) Indices
• MCV • - CORRECT ANSWER - mean cell volume indicates RBC size
• MCH - CORRECT ANSWER - mean cell hemoglobin - weight of hemoglobin
contained in RBC
• MCHC - CORRECT ANSWER - mean cell hemoglobin content - average concentration
of hemoglobin in RBC
• MCH, MCHC decreased in - CORRECT ANSWER - microcytic anemia,
• MCH, MCHC increased - CORRECT ANSWER - macrocytic anemia
• One of the largest organs in the body - CORRECT ANSWER - Bone Marrow
Bone Marrow Defined as - CORRECT ANSWER - tissue located within the cavities of
the cortical bones
,Bone Marrow Cavities consist of - CORRECT ANSWER - trabecular bone resembling a
honeycomb-like structure
• More than 100 times blood cells in your ———- than there are people in the world! -
CORRECT ANSWER - Bone Marrow
Bone marrow is located within - CORRECT ANSWER - within the cavities of the cortical
bones
Bone Marrow two types - CORRECT ANSWER - Red marrow Yellow marrow
Red marrow - CORRECT ANSWER - hematopoietically active marrow Produces cells
Yellow marrow - CORRECT ANSWER - hematopoietically inactive marrow composed
primarily of adipocytes (fat cells)
Can return to active under right contions (example hemolysis) - CORRECT ANSWER -
Yellow marrow
• Not all bones contain - CORRECT ANSWER - bone marrow
During infancy and early childhood, bone marrow - CORRECT ANSWER - is mostly red
active marrow in all bones
Sites of hematopoiesis decreases - CORRECT ANSWER - during fetal development
Bone Marrow Retrogression occurs - CORRECT ANSWER - beginning at age 5-7
, - Red marrow is restricted to - CORRECT ANSWER - flat bones, sternum, vertebrae,
pelvis, ribs, skull and proximal long bones
• By adulthood, marrow is - CORRECT ANSWER - 50% blood cells and 50% fat
Blood & nutrients are supplied by the - CORRECT ANSWER - periosteal arteries that
coil around the central vein, passing along the bone canal
sinuses - CORRECT ANSWER - • Sinus is a venous vessel found in the RES that is
larger than a capillary but smaller than a vein
Sinuses hook up to - CORRECT ANSWER - larger veins and return into main circulation
Bone Marrow Blood Flow - CORRECT ANSWER - Blood & nutrients are supplied by
the periosteal arteries that coil around the central vein, passing along the bone canal - Branches
and forms capillaries then sinuses
Red Marrow Composed of - CORRECT ANSWER - extravascular cords that contain all
of the developing blood cell lineages, stem and progenitor cells, adventitial cells, and
macrophages
Composed of extravascular cords - CORRECT ANSWER - Red Marrow
Red Marrow - Cells are in - CORRECT ANSWER - semi-liquid cords or wedges between
sinuses supported by trabeculae of spongy bone and reticular adventitial cells Cells develop in
specific niches within the cords
Trabeculae - CORRECT ANSWER - calcified bone
Location of Cell Development RBCS - CORRECT ANSWER - develop in small clusters
adjacent to the outer surfaces of the vascular sinuses
ACTUAL Questions and CORRECT
Answers
Anticoagulants - CORRECT ANSWER - EDTA (most common), heparin, sodium citrate
Types of Normal Blood Cells Found in Peripheral Blood - CORRECT ANSWER - • Red
Blood Cells
Platelets
White Blood Cells
Lymphocyte
Monocyte
(Granulocytes)
Eosinophil
Basophil (baso)
Segmented neutrophil
• Band neutrophil
"cyte" - CORRECT ANSWER - cell
Intramedullary hemolysis - CORRECT ANSWER - within bone marrow cell break-up
Extramedullary hemolysis - CORRECT ANSWER - outside bone marrow cell lysis
- Cell destruction outside the bone marrow - CORRECT ANSWER - Extramedullary
hemolysis
Erythroid hyperplasia - CORRECT ANSWER - increased red cell formation
,Lymphopenia - CORRECT ANSWER - decreased number of lymphs
Eosinophilia - CORRECT ANSWER - increased number of eos
Polycythemia - CORRECT ANSWER - All cells in the blood are increased many cells
increased
Intravascular Hemolysis - CORRECT ANSWER - inside vessel breakdown of RBCS
CBC includes - CORRECT ANSWER - WBC, RBC, platelet count, hemoglobin (hgb),
hematocrit (hct) Indices
• MCV • - CORRECT ANSWER - mean cell volume indicates RBC size
• MCH - CORRECT ANSWER - mean cell hemoglobin - weight of hemoglobin
contained in RBC
• MCHC - CORRECT ANSWER - mean cell hemoglobin content - average concentration
of hemoglobin in RBC
• MCH, MCHC decreased in - CORRECT ANSWER - microcytic anemia,
• MCH, MCHC increased - CORRECT ANSWER - macrocytic anemia
• One of the largest organs in the body - CORRECT ANSWER - Bone Marrow
Bone Marrow Defined as - CORRECT ANSWER - tissue located within the cavities of
the cortical bones
,Bone Marrow Cavities consist of - CORRECT ANSWER - trabecular bone resembling a
honeycomb-like structure
• More than 100 times blood cells in your ———- than there are people in the world! -
CORRECT ANSWER - Bone Marrow
Bone marrow is located within - CORRECT ANSWER - within the cavities of the cortical
bones
Bone Marrow two types - CORRECT ANSWER - Red marrow Yellow marrow
Red marrow - CORRECT ANSWER - hematopoietically active marrow Produces cells
Yellow marrow - CORRECT ANSWER - hematopoietically inactive marrow composed
primarily of adipocytes (fat cells)
Can return to active under right contions (example hemolysis) - CORRECT ANSWER -
Yellow marrow
• Not all bones contain - CORRECT ANSWER - bone marrow
During infancy and early childhood, bone marrow - CORRECT ANSWER - is mostly red
active marrow in all bones
Sites of hematopoiesis decreases - CORRECT ANSWER - during fetal development
Bone Marrow Retrogression occurs - CORRECT ANSWER - beginning at age 5-7
, - Red marrow is restricted to - CORRECT ANSWER - flat bones, sternum, vertebrae,
pelvis, ribs, skull and proximal long bones
• By adulthood, marrow is - CORRECT ANSWER - 50% blood cells and 50% fat
Blood & nutrients are supplied by the - CORRECT ANSWER - periosteal arteries that
coil around the central vein, passing along the bone canal
sinuses - CORRECT ANSWER - • Sinus is a venous vessel found in the RES that is
larger than a capillary but smaller than a vein
Sinuses hook up to - CORRECT ANSWER - larger veins and return into main circulation
Bone Marrow Blood Flow - CORRECT ANSWER - Blood & nutrients are supplied by
the periosteal arteries that coil around the central vein, passing along the bone canal - Branches
and forms capillaries then sinuses
Red Marrow Composed of - CORRECT ANSWER - extravascular cords that contain all
of the developing blood cell lineages, stem and progenitor cells, adventitial cells, and
macrophages
Composed of extravascular cords - CORRECT ANSWER - Red Marrow
Red Marrow - Cells are in - CORRECT ANSWER - semi-liquid cords or wedges between
sinuses supported by trabeculae of spongy bone and reticular adventitial cells Cells develop in
specific niches within the cords
Trabeculae - CORRECT ANSWER - calcified bone
Location of Cell Development RBCS - CORRECT ANSWER - develop in small clusters
adjacent to the outer surfaces of the vascular sinuses