NUR 378
NUR 378 Exam 2: Pharmacology – Concordia
University St. Paul.
upper respiratory tract - ANS nose
mouth
throat
conditions of the upper respiratory tract - ANS nasal allergies
seasonal allergic rhinitis
urticaria
common cold
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drugs used to treat the upper respiratory tract - ANS antihistamines
decongestants
expectorants
MOA antihistamines - ANS block histamine receptors on surfaces of basophils
and mast cells
which...
prevents release of histamine
general MOA decongestants - ANS shrink engorged nasal mucous
membranes relieving nasal stuffiness
decongestant drugs - ANS oxymetazoline
MOA oxymetazoline - ANS stimulates alpha-adrenergic receptors causing
arteriole constriction at the nostrils helping to drain nasal secretions
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MOA expectorants - ANS reduce secretion thickness by increasing hydration
of respiratory tract
lower respiratory tract - ANS trachea
bronchi
lungs
conditions of the lower respiratory tract - ANS asthma
COPD
asthma - ANS NARROWING of the bronchi and bronchioles
usually triggered by an allergen
COPD - ANS OBSTRUCTION of the lungs
usually constant
NUR 378