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Test Bank for Integrated Cardiopulmonary Pharmacology 6th Edition by Bruce J. Colbert | All Chapters 1-15 | ISBN: 9781517813895

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Test Bank for Integrated Cardiopulmonary Pharmacology 6th Edition by Bruce J. Colbert | All Chapters 1-15 | ISBN: 9781517813895. 1. Which term best describes the study of drugs and their action on the body? a. Therapeutics b. Pharmacology c. Pharmacotherapy d. Disease management 2. The most common source of drugs today is: a. Plants. b. Animals. c. Chemical synthesis. d. Genetic bioengineering. 3. The phase of drug testing that is performed to look for rare or serious adverse effects after the drug is marketed is: a. Phase I. b. Phase II. c. Phase III. d. Phase IV. Colbert_icp3_TestBank_questions Page 2 of 157 4. What organization is officially responsible for establishing public standards that approved drugs must continue to meet? a. The Physicians’ Desk Reference (PDR) b. The American Hospital Formulary Service (AHFS) c. The United States Pharmacopeia (USP) d. The Food and Drug Administration (FDA) 5. The name given to a drug that is considered the nonproprietary name and is not owned by any particular pharmaceutical company is the: a. Chemical name. b. Generic name. c. Trade name. d. Brand name. . 6. A 21-year-old pregnant female has been exposed to the drug Virazole, which has been reported to cause damage to the fetus. This type of drug exposure is referred to as: a. An adverse drug reaction (ADR). b. A life-threatening reaction. c. Hypersensitivity. d. Teratogenicity. 7. The agency that regulates drug testing and approves new drugs is the: a. Center for Drug Evaluation and Research (CDER). b. Centers for Disease Control and Prevention (CDC). c. National Institutes of Health (NIH). d. Food and Drug Administration (FDA). Colbert_icp3_TestBank_questions Page 3 of 157 8. Drugs that do not go directly into the systemic circulation after being absorbed and are metabolized through the liver describes a: a. Steady state. b. First-pass effect. c. Therapeutic range. d. Half-life. 9. A physician would like a patient to receive acetaminophen via the enteral route. Your choice of administration may include: I. Oral. II. Nasogastric. III. Rectal. a. I b. I and II c. I and III d. I, II, and III 10. Administration of 80 mg propranolol given orally (PO) produces the same response as 1 mg intravenously (IV). The difference in dosage is explained by: a. The first-pass effect. b. Bioavailability. c. Protein binding. d. Metabolism. 11. The most common and convenient route of drug administration is: a. Oral. Colbert_icp3_TestBank_questions Page 4 of 157 b. Inhalation. c. Sublingual. d. Transdermal. 12. A malnourished patient is susceptible to an increase in drug response because of all except which of the following? a. A malnourished patient has less serum albumin. b. The free, unbound drug is an active drug and will lead to greater drug response. c. Less drug is absorbed systemically. d. Much of the drug will be free within the bloodstream. 13. The effect of administering a water-soluble drug to an infant, who has a higher percentage of total body water compared to an adult, would be: a. Decreased effect. b. The same effect. c. Increased effect. d. An additive effect. 14. The mechanisms responsible for metabolism of rifampin in the liver include: I. Drug oxidation. II. Enzyme inhibition. III. The cytochrome P-450 system. a. I and II b. I and III c. II and III d. I, II, and III Colbert_icp3_TestBank_questions Page 5 of 157 15. After drugs are metabolized, they can be eliminated from the body through the: a. Skin. b. Lungs. c. Feces and urine. d. All of the above. 18. When a drug binds to a receptor site, all except which of the following can occur? a. An ion channel can be opened or closed. b. Biochemical messengers that initiate chemical reactions can be activated. c. A normal cellular function can be turned on or off. d. The therapeutic response produced is directly proportional to the number of sites occupied. 19. A drug that does not elicit a response: a. Is an agonist. b. Increases drug action. c. Is an antagonist. d. Activates the receptor. 20. A cell that becomes less responsive to a drug after exposure over time is a condition called: a. Tolerance. b. Desensitization. c. Dependence. d. Low therapeutic index.

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2025/2026
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Tentamen (uitwerkingen)
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  • bruce j colbert

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Test Bank for Integrated Cardiopulmonary
Pharmacology 6th Edition by Bruce J. Colbert
| All Chapters 1-15 | ISBN: 9781517813895

Chapter 1
MULTIPLE CHOICE
Choose the one alternative that best completes the statement or answers the
question.
1. Which term best describes the study of drugs and their action on the
body?
a. Therapeutics
b. Pharmacology
c. Pharmacotherapy
d. Disease management
2. The most common source of drugs today is:
a. Plants.
b. Animals.
c. Chemical synthesis.
d. Genetic bioengineering.
3. The phase of drug testing that is performed to look for rare or serious
adverse effects after the drug is marketed is:
a. Phase I.
b. Phase II.
c. Phase III.
d. Phase IV.



Page 1 of 157

, Colbert_icp3_TestBank_questions




4. What organization is officially responsible for establishing public
standards that approved drugs must continue to meet? a. The
Physicians’ Desk Reference (PDR)
b. The American Hospital Formulary Service (AHFS)
c. The United States Pharmacopeia (USP)
d. The Food and Drug Administration (FDA)
5. The name given to a drug that is considered the nonproprietary name and
is not owned by any particular pharmaceutical company is the:
a. Chemical name.
b. Generic name.
c. Trade name.
d. Brand name.
.
6. A 21-year-old pregnant female has been exposed to the drug Virazole,
which has been reported to cause damage to the fetus. This type of drug
exposure is referred to as:
a. An adverse drug reaction (ADR).
b. A life-threatening reaction.
c. Hypersensitivity.
d. Teratogenicity.
7. The agency that regulates drug testing and approves new drugs is the:
a. Center for Drug Evaluation and Research (CDER).
b. Centers for Disease Control and Prevention (CDC).
c. National Institutes of Health (NIH).
d. Food and Drug Administration (FDA).



Page 2 of 157

, Colbert_icp3_TestBank_questions




8. Drugs that do not go directly into the systemic circulation after being
absorbed and are metabolized through the liver describes a:
a. Steady state.
b. First-pass effect.
c. Therapeutic range.
d. Half-life.
9. A physician would like a patient to receive acetaminophen via the enteral
route. Your choice of administration may include:
I. Oral.
II. Nasogastric.
III. Rectal.
a. I
b. I and II
c. I and III
d. I, II, and III
10. Administration of 80 mg propranolol given orally (PO) produces the
same response as 1 mg intravenously (IV). The difference in dosage is
explained by:
a. The first-pass effect.
b. Bioavailability.
c. Protein binding.
d. Metabolism.
11. The most common and convenient route of drug administration is:
a. Oral.



Page 3 of 157

, Colbert_icp3_TestBank_questions




b. Inhalation.
c. Sublingual.
d. Transdermal.
12. A malnourished patient is susceptible to an increase in drug response
because of all except which of the following?
a. A malnourished patient has less serum albumin.
b. The free, unbound drug is an active drug and will lead to greater
drug response.
c. Less drug is absorbed systemically.
d. Much of the drug will be free within the bloodstream.
13. The effect of administering a water-soluble drug to an infant, who has a
higher percentage of total body water compared to an adult, would be:
a. Decreased effect.
b. The same effect.
c. Increased effect.
d. An additive effect.
14. The mechanisms responsible for metabolism of rifampin in the liver
include:
I. Drug oxidation.
II. Enzyme inhibition.
III. The cytochrome P-450 system. a. I and II
b. I and III
c. II and III
d. I, II, and III




Page 4 of 157

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