1|Page
NR546 FINAL EXAM AND STUDY GUIDE NEWEST 2025
TEST BANK| ADVANCED PHARMACOLOGY
PSYCHOPHARMACOLOGY FOR THE PMHNP FINAL
EXAM PREP WITH COMPLETE 550 REAL EXAM
QUESTIONS AND CORRECT VERIFIED ANSWERS/
ALREADY GRADED A+ (MOST RECENT!!)
Which medication is considered the best tolerated SSRI?
A. Venlafaxine
B. Bupropion
C. Setraline
D. Escitalopram – Correct Answer - D. Escitalopram
During a 4 week follow up appointment, Rashida, who is prescribed
Sertraline 25mg qAM reports slight improvement in depression
symptoms and tolerating medication well. Which of the following
should the PMHNP do?
A. Increase Setraline dose
B. Switch to an SNRI
C. Switch to a different SSRI
D. Add Trazodone qHS for sleep. – Correct Answer - A. Increase
Setraline dose
pg. 1
,2|Page
Which medication should be avoided for the 66 year patient diagnosed
with major depressive disorder and anxiety with a reported fall 3 months
ago?
A. Citalopram
B. Setraline
C. Paroxetine
D. Aripiprazole – Correct Answer - C. Paroxetine
Which of the following symptoms is NOT an adverse effect associated
with the acute use of opioids?
A. Sedation
B. Respiratory depression
C. Immunosuppression
D. Itching – Correct Answer - C. Immunosuppression
When dosing citalopram for Lynee, a 72 year old patient, the PMHNP
understands to dose at 1/2 dose due to the increased risk of
A. delirium
B. polypharmacy
C. falls
D. QTc prolongation – Correct Answer - D. QTc prolongation
Which SSRI has a mild antihistamine effect?
pg. 2
,3|Page
A. Paroxetine
B. Fluoxetine
C. Citalopram
D. Sertraline – Correct Answer - C. Citalopram
Which of the following medication class is approved for first line
treatment for OCD?
A. Atypical antipsychotics
B. Benzodiazepines
C. MAOI
D. SSRI – Correct Answer - D. SSRI
Which medication should the PMHNP prescribe for a patient diagnosed
with major depressive disorder but takes multiple medications for other
chronic conditions?
A. Sertraline
B. Escitalopram
C. Buspirone
D. Clonazepam – Correct Answer - B. Escitalopram
The patient reports suffering from insomnia and anxiety. Which SSRI
should be prescribed?
A. Paroxetine
pg. 3
, 4|Page
B. Duloxetine
C. Fluoxetine
D. Venlafaxine – Correct Answer - A. Paroxetine
Tricyclic antidepressants (TCA) act as antagonists on which of the
following neurotransmitters?
A. Acetylcholine and Dopamine
B. Histamine and Acetylcholine
C. Dopamine and Histamine
D. Serotonin and Norepinephrine – Correct Answer - B. Histamine and
Acetylcholine
Which foods should the PMHNP educate their patient to avoid while
they are taking Selegiline?
A. Nuts, milk and wheat
B. Aged wine, cheeses, and meats
C. Green leafy vegetables and tomatoes
D. Grapefruit and grapefruit juice – Correct Answer - B. Aged wine,
cheeses, and meats
Which neurotransmitter is associated with reward and addiction?
A. Norepinephrine
B. GABA
pg. 4
NR546 FINAL EXAM AND STUDY GUIDE NEWEST 2025
TEST BANK| ADVANCED PHARMACOLOGY
PSYCHOPHARMACOLOGY FOR THE PMHNP FINAL
EXAM PREP WITH COMPLETE 550 REAL EXAM
QUESTIONS AND CORRECT VERIFIED ANSWERS/
ALREADY GRADED A+ (MOST RECENT!!)
Which medication is considered the best tolerated SSRI?
A. Venlafaxine
B. Bupropion
C. Setraline
D. Escitalopram – Correct Answer - D. Escitalopram
During a 4 week follow up appointment, Rashida, who is prescribed
Sertraline 25mg qAM reports slight improvement in depression
symptoms and tolerating medication well. Which of the following
should the PMHNP do?
A. Increase Setraline dose
B. Switch to an SNRI
C. Switch to a different SSRI
D. Add Trazodone qHS for sleep. – Correct Answer - A. Increase
Setraline dose
pg. 1
,2|Page
Which medication should be avoided for the 66 year patient diagnosed
with major depressive disorder and anxiety with a reported fall 3 months
ago?
A. Citalopram
B. Setraline
C. Paroxetine
D. Aripiprazole – Correct Answer - C. Paroxetine
Which of the following symptoms is NOT an adverse effect associated
with the acute use of opioids?
A. Sedation
B. Respiratory depression
C. Immunosuppression
D. Itching – Correct Answer - C. Immunosuppression
When dosing citalopram for Lynee, a 72 year old patient, the PMHNP
understands to dose at 1/2 dose due to the increased risk of
A. delirium
B. polypharmacy
C. falls
D. QTc prolongation – Correct Answer - D. QTc prolongation
Which SSRI has a mild antihistamine effect?
pg. 2
,3|Page
A. Paroxetine
B. Fluoxetine
C. Citalopram
D. Sertraline – Correct Answer - C. Citalopram
Which of the following medication class is approved for first line
treatment for OCD?
A. Atypical antipsychotics
B. Benzodiazepines
C. MAOI
D. SSRI – Correct Answer - D. SSRI
Which medication should the PMHNP prescribe for a patient diagnosed
with major depressive disorder but takes multiple medications for other
chronic conditions?
A. Sertraline
B. Escitalopram
C. Buspirone
D. Clonazepam – Correct Answer - B. Escitalopram
The patient reports suffering from insomnia and anxiety. Which SSRI
should be prescribed?
A. Paroxetine
pg. 3
, 4|Page
B. Duloxetine
C. Fluoxetine
D. Venlafaxine – Correct Answer - A. Paroxetine
Tricyclic antidepressants (TCA) act as antagonists on which of the
following neurotransmitters?
A. Acetylcholine and Dopamine
B. Histamine and Acetylcholine
C. Dopamine and Histamine
D. Serotonin and Norepinephrine – Correct Answer - B. Histamine and
Acetylcholine
Which foods should the PMHNP educate their patient to avoid while
they are taking Selegiline?
A. Nuts, milk and wheat
B. Aged wine, cheeses, and meats
C. Green leafy vegetables and tomatoes
D. Grapefruit and grapefruit juice – Correct Answer - B. Aged wine,
cheeses, and meats
Which neurotransmitter is associated with reward and addiction?
A. Norepinephrine
B. GABA
pg. 4
