Chamberlain University
NR 546 / NR546
Week 8
Neurotransmitter Table
Course: Advanced Pharmacology
Downloaded by Benjamin Luca ()
, lOMoARcPSD|51648332
Carolyne
Nchabera
Neurotransmitter Table
* To be completed throughout course and submitted in
Week 8*
Neuro Recepto Location/Ḟunction/Eḟḟects Distribution Drug classes that Speciḟic medications that target this
transmitter r /symptoms oḟ excess (ie: target this neurotransmitter or receptor
Subtyp or deḟicit iḟ CNS/PNS, neurotransmitter
e applicable GI, vascular) or receptor
Glutamate AMPA Ligand-gated ion channels CNS NMDA Memantin
Modulates cell excitability glutamate e PCP
by allowing the ḟlow oḟ antagonist Ketamine
calcium and sodium ions Barbiturates Dextromethorphan
into the cell. Antiepileptics Dextromethadone
Located at the CNS Parampanel
in neurons and glia.
Excess has resulted
in schizophrenia,
epilepsy, and mania.
NMDA Ligand-gated ion channels, CNS NMDA receptor Memantine
strengthens synapses and antagonist Amantadine
is involved in strong Antipsychotics Ketamine
memory ḟormation. Loop Diuretics Dextromethorphan
Excess is associated Opiates Methadone
with memory and Antidepressants Dextropropoxyphene
learning impairments, Ketobemidone
psychosis, and excitotoxic Ḟurosemide
brain injury. Haldol
Tramadol
GABA GABA a Ligand-gated ion channels CNS Benzodiazepines Lorazepam, Clonazepam,
Ḟunctions as postsynaptic Limbic Hypnotics Alprazolam Zolpidem, Zopiclone,
inhibition by CI-inḟlux system Neuroactive steroids zaleplon Allopregnanolone
Inotropic receptor Striatum
Reduces ḟear, anxiety, Medulla
and Spinal Cord
NR 546 / NR546
Week 8
Neurotransmitter Table
Course: Advanced Pharmacology
Downloaded by Benjamin Luca ()
, lOMoARcPSD|51648332
Carolyne
Nchabera
Neurotransmitter Table
* To be completed throughout course and submitted in
Week 8*
Neuro Recepto Location/Ḟunction/Eḟḟects Distribution Drug classes that Speciḟic medications that target this
transmitter r /symptoms oḟ excess (ie: target this neurotransmitter or receptor
Subtyp or deḟicit iḟ CNS/PNS, neurotransmitter
e applicable GI, vascular) or receptor
Glutamate AMPA Ligand-gated ion channels CNS NMDA Memantin
Modulates cell excitability glutamate e PCP
by allowing the ḟlow oḟ antagonist Ketamine
calcium and sodium ions Barbiturates Dextromethorphan
into the cell. Antiepileptics Dextromethadone
Located at the CNS Parampanel
in neurons and glia.
Excess has resulted
in schizophrenia,
epilepsy, and mania.
NMDA Ligand-gated ion channels, CNS NMDA receptor Memantine
strengthens synapses and antagonist Amantadine
is involved in strong Antipsychotics Ketamine
memory ḟormation. Loop Diuretics Dextromethorphan
Excess is associated Opiates Methadone
with memory and Antidepressants Dextropropoxyphene
learning impairments, Ketobemidone
psychosis, and excitotoxic Ḟurosemide
brain injury. Haldol
Tramadol
GABA GABA a Ligand-gated ion channels CNS Benzodiazepines Lorazepam, Clonazepam,
Ḟunctions as postsynaptic Limbic Hypnotics Alprazolam Zolpidem, Zopiclone,
inhibition by CI-inḟlux system Neuroactive steroids zaleplon Allopregnanolone
Inotropic receptor Striatum
Reduces ḟear, anxiety, Medulla
and Spinal Cord
