UWSA1 – Questions With In Depth Solutions
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Terms in this set (207)
breakdown product serotonin
5-hydroxyindoleacetic acid
(5-HIAA)
carcinoid tumors
hypoxemia
ARDS definition bilateral pulm edema
NO fluid overload or heart failure
trauma, fat emoblism
injury alveolar pneumocytes, pulm endothelium -->
ARDS moa
inflamm cytokines released --> recruit neutrophils to
lungs --> release more inflamma mediators (proteases,
free radicals)
increase capillary permeability
ARDS result intraalveolar fluid accumulation
hyaline membrane formation
mesangial expansion
glomerular basement membrane
diabetic nephropathy thickening
glomerular sclerosis (nodular =
Kimmelstiel-Wilson lesion)
thickening vasa recta capillaries
intermittent tubular necrosis
analgesic abuse
papillary necrosis
nephropathy
focal + segmental glomerulosclerosis
interstitial infiration
fibrosis
AV node location interatrial septum near tricuspid orifice
bundle of His, left + right along interventricular septum
bundle branches location
,purkinje fiber location ventricular myocardium
Park At Venture Avenue
cardiac tissue conduction Purkinje
velocity Atrial muscle
Ventricular muscle
AV node
malignant transformation to osteosarcoma
destruction normal travecular bone patter
Paget dz complication
mixed radiodense (sclerotic) + radiolucent (lytic) areas
periosteal new bone formation w/ lifting of the
periosteum
avascular necrosis crescent sign --> subchondral collapse @ femoral head
radiographic finding
osteophytes
osteoarthritis radiographic
joint-space narrowing
findings
improve w/ over-the-counter analgesics
abnormal sensation of foreign body, tightness, fullness
globus sensation
in throat
substernal goiter thyroid lobe grow into thoracic cavity inlet
teratogenic
excessive vita a it... 1st trimester organogenesis (microcephaly, cardiac
anomalies, early epiphyseal closure, growth retardation,
spontaneous abortion)
tx N/V pregnancy pyridoxine (vita B6)
silaic acid analogue
oseltamivir inhibits neuraminidases influenze A + B
prevent release newly formed viral particles
, proteins destined for export from cell
posttranslational cleavage
collagen (procollagen peptidases)
ex
trypsinogen (enterokinase)
DNA fragments in multiples of 180 base pairs on gel
electrophoresis
DNA laddering
APOPTOSIS
malig or nonmalig
clonal expansion single cell produces numerous identical daughter cells
antigen-specific lymphocytes in response to infection
phase 1: CYP-mediated hepatic oxidative reduction
benzo metabolism
phase 2: glucuronide conjugation
lorazepam
only glucuronide
oxazepam
conjugation
temazepam
germline mosaicism
genetic mutation in
offspring NOT parents
multiple genetically different gamete cell lines
cannot be passed to offspring (unlike germline
somatic mutation
mutation)
antigen-stimulated T lymphocytes
IL-2 produced exclusively
by... stim growth + differentiation of T cells, B cells, NK cells,
macrophages
IL-1 produced by mononuclear phagocytes
TNF-alpha produced by macrophages
monocytes
macrophages
INF-alpha produced by
B cells
NK cells
Save
Terms in this set (207)
breakdown product serotonin
5-hydroxyindoleacetic acid
(5-HIAA)
carcinoid tumors
hypoxemia
ARDS definition bilateral pulm edema
NO fluid overload or heart failure
trauma, fat emoblism
injury alveolar pneumocytes, pulm endothelium -->
ARDS moa
inflamm cytokines released --> recruit neutrophils to
lungs --> release more inflamma mediators (proteases,
free radicals)
increase capillary permeability
ARDS result intraalveolar fluid accumulation
hyaline membrane formation
mesangial expansion
glomerular basement membrane
diabetic nephropathy thickening
glomerular sclerosis (nodular =
Kimmelstiel-Wilson lesion)
thickening vasa recta capillaries
intermittent tubular necrosis
analgesic abuse
papillary necrosis
nephropathy
focal + segmental glomerulosclerosis
interstitial infiration
fibrosis
AV node location interatrial septum near tricuspid orifice
bundle of His, left + right along interventricular septum
bundle branches location
,purkinje fiber location ventricular myocardium
Park At Venture Avenue
cardiac tissue conduction Purkinje
velocity Atrial muscle
Ventricular muscle
AV node
malignant transformation to osteosarcoma
destruction normal travecular bone patter
Paget dz complication
mixed radiodense (sclerotic) + radiolucent (lytic) areas
periosteal new bone formation w/ lifting of the
periosteum
avascular necrosis crescent sign --> subchondral collapse @ femoral head
radiographic finding
osteophytes
osteoarthritis radiographic
joint-space narrowing
findings
improve w/ over-the-counter analgesics
abnormal sensation of foreign body, tightness, fullness
globus sensation
in throat
substernal goiter thyroid lobe grow into thoracic cavity inlet
teratogenic
excessive vita a it... 1st trimester organogenesis (microcephaly, cardiac
anomalies, early epiphyseal closure, growth retardation,
spontaneous abortion)
tx N/V pregnancy pyridoxine (vita B6)
silaic acid analogue
oseltamivir inhibits neuraminidases influenze A + B
prevent release newly formed viral particles
, proteins destined for export from cell
posttranslational cleavage
collagen (procollagen peptidases)
ex
trypsinogen (enterokinase)
DNA fragments in multiples of 180 base pairs on gel
electrophoresis
DNA laddering
APOPTOSIS
malig or nonmalig
clonal expansion single cell produces numerous identical daughter cells
antigen-specific lymphocytes in response to infection
phase 1: CYP-mediated hepatic oxidative reduction
benzo metabolism
phase 2: glucuronide conjugation
lorazepam
only glucuronide
oxazepam
conjugation
temazepam
germline mosaicism
genetic mutation in
offspring NOT parents
multiple genetically different gamete cell lines
cannot be passed to offspring (unlike germline
somatic mutation
mutation)
antigen-stimulated T lymphocytes
IL-2 produced exclusively
by... stim growth + differentiation of T cells, B cells, NK cells,
macrophages
IL-1 produced by mononuclear phagocytes
TNF-alpha produced by macrophages
monocytes
macrophages
INF-alpha produced by
B cells
NK cells
