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1. A 32-year-old woman is being evaluated for alcoholism. This is her first time in
treatment. She has a 15-year history of alcohol dependence. Which of the following is
the most appropriate medication? (correct Answer) - ✅✅ Naltrexone
2. A 14-year-old boy comes to the office for an annual examination. During the
interview, he tells his physician that he has switched from smoking cigarettes to using
smokeless tobacco because he does not want to get lung cancer. The physician should
tell the patient that he is now at increased risk for cancer of which of the following?
(correct Answer) - ✅✅ Esophageal
3. A 32-year-old woman comes to the office seeking assistance with smoking cessation.
She has smoked two packs of cigarettes daily for the past eight years. She has
attempted to quit twice before but was unable to overcome the withdrawal symptoms.
She is using a nicotine transdermal system to assist her in smoking cessation. Which
of the following is a side effect she should still expect to experience during her
withdrawal of nicotine? (correct Answer) - ✅✅ Impaired reaction time
4. A 42-year-old physician who specializes in ear, nose, and throat conditions is being
interviewed for a position by a hospital. She has active licenses in Arizona, Idaho, and
Missouri (her last place of residence for seven years). The training listed on her CV
received has been verified by a primary source. The National Data Bank contains no
adverse records. Which of the following is troublesome to require? (correct Answer) -
✅✅ Polygraph test
,5. A 45-year-old injection drug user was started on methadone maintenance one
month prior to his current hospitalization for pneumonia. On a routine inpatient
electrocardiogram, he has a prolonged QT interval. In addition to his methadone dose,
which of the following factors increases his risk for developing an arrhythmia?
(correct Answer) - ✅✅ Hypokalemia
6. A 30-year-old woman began taking alprazolam 0.25 mg four times daily two weeks
ago for generalized anxiety disorder (GAD). She now has increased sedation as
treatment continues. For this patient, select the most appropriate term: (correct
Answer) - ✅✅ Sensitization
7. A 45-year-old woman who has been taking alprazolam 0.5 mg four times daily for
GAD ruminates about the next dose beginning two hours after the last dose. For this
patient, select the most appropriate term: (correct Answer) - ✅✅ Pseudowithdrawal
8. A 45-year-old man took alprazolam for GAD for one year. He was weaned off the
medication over a three-month period. Two weeks after complete cessation, he notices
increased worry. For this patient, select the most appropriate term: (correct Answer)
- ✅✅ Symptom recurrence (not true withdrawal)
9. A 45-year-old man was placed on alprazolam 0.25 mg three times daily for GAD and
treatment was successful. He was tapered off of the medication over three months.
One week after complete cessation, he is tormented by anxiety and is sleeping only
two hours per night. For this patient, select the most appropriate term: (correct
Answer) - ✅✅ Rebound (not true withdrawal)
10. A 36-year-old man who has a 20-year history of smoking cigarettes comes to the
office for counseling about smoking cessation. He has heard that "light" cigarettes may
be safer and less addictive and asks whether they could help him stop smoking. Which
,of the following statements about light cigarettes is supported by scientific evidence?
A: Smokers adjust their current nicotine level by adjusting puffing habits (correct
Answer) - ✅✅ Smokers adjust their current nicotine level by adjusting puffing habits
11. A 50-year-old man with alcohol dependency is hospitalized with signs of acute
withdrawal. Which of the following drugs should be administered to prevent
Wernicke's encephalopathy in this patient? (correct Answer) - ✅✅ thiamine
12. A 25-year-old man is brought to the emergency department by his partner because
of a two-day history of agitation. The patient says he left his work early because his
boss was spying on him. His speech is pressured. He says he has been taking
medication for the past three months. His partner reports that the patient had been
taking more than the prescribed dose because he was preparing for a college
examination. Which of the following medications is the most likely cause of his
symptoms? (correct Answer) - ✅✅ methylphenidate
13. A 45-year-old man has jaundice caused by chronic alcohol abuse. His physician
spends several minutes asking him about his drinking habits and encourages him to
consider stopping drinking. The patient is not ready to contemplate stopping at that
visit, but the physician brings up the topic in a nonthreatening manner at subsequent
visits until the patient decides to take some action to stop drinking. The physician
then offers the patient several choices for accomplishing that goal. This framework of
brief interventions to promote healthful behavior is known as which of the following?
(correct Answer) - ✅✅ motivational interviewing
14. A 17-year-old boy comes to the office for a sports physical examination. When
asked about his drug and alcohol use, he discloses that he recently started smoking
marijuana. Which of the following is the most likely source from which he obtained
the marijuana? (correct Answer) - ✅✅ Friends
, 15. A retired physician works eight hours per week at a private general medicine clinic
in a rural community. The practice serves primarily economically stable, Medicare-
eligible patients. Recently, the physician learned and implemented a new diagnostic
test with a sensitivity of 91% and specificity of 94% to diagnose a disease. However,
one of the physician's patients believes he has been incorrectly diagnosed as a result of
this test and retains a lawyer to file a suit against the physician. The successful court
argument against the use of the test by the physician is most likely based on which of
the following? (correct Answer) - ✅✅ Cases in the population per year (prevalence)
16. Which of the following disorders would most likely benefit from treatment with
cannabinoid type 1 (CB1) receptor antagonists? (correct Answer) - ✅✅ Obesity(ref :
Trends Neurosci. 2006 Feb 14; Links Involvement of the endocannabinoid system in
drug addiction. Maldonado R, Valverde O, Berrendero F. 6:Gadde KM.
Endocannabinoid receptor antagonists and other emerging pharma-cological
strategies for weight reduction. Curr Drug Targets Cardiovasc Haematol Disord. 2005
Dec;5(6):549-56.)
17. A patient comes to the emergency department because he is "hearing colors and
smelling sounds." He reports taking an unknown substance at a party several hours
ago. Vital signs show increased pulse rate and blood pressure. The patient is quite
agitated and wants these effects to go away. Which of the following drugs is most
likely to cause these effects? (correct Answer) - ✅✅ Lysergic acid diethylamide
(LSD)
18. Which of the following neurotransmitters is most closely associated with the
function of the brain reward circuitry? (correct Answer) - ✅✅ Dopamine
19. A 19-year-old college student is brought to the emergency department after using
drugs for the first time. He says he initially felt as if he was "melting through the floor,"
but now feels as if he is "floating through alternate realities." The experience lasts
about one-half hour. Which of the following substances is the most likely cause of his