RNA & Proteins
Central
Dogma Theory that genetic information flows only in one
z
direction : DNA RNA Protein or RNA- Protein
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However ,
in some cases RNA can be Wanscibed
reverse to DNA
Nucleotide structure
Each monomer of DNA is a nucleotide
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Sugar phosphate group &nitogeneous
consists :
of
-
, ,
base
RNA by2,
o
inters
Deoxyribose in DNA nbose in
-
,
Polymer molecules
Nucleotides
join together in condensation reactions
-
,
forming a
hydrogen bond and releasing a molecule
of water
per condensation reaction
Vanities of nucleotides
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structres of nucleotides determines
their
hydrogen bonding potential
Pyrmidines bond with
purines
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Forming a heux
* strands
negative charges the phosphate backbone
repel
-
on
are anti
each other , the bases stack inside the helix -
parallel
structure with equal spacing . To
between them
fit bases and sugars , the backbone spirals ,
creating
a
major and minor
groove . CG bonds stronger asthey
bonds
have 3
hydrogen
, DNA vs RNA
RNA uses nibose
sugar
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DNA stable tran RNA CRNA
more
degrades quicker)
-
reacility and decreases
The 2 ots that RNA has increases
stability
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RNA Uracil instead of thymine important for DNA
uses repair
-
,
mechanisms
-DNA is its stable
a better
storage molecule as more , it can be
packaged and its
longer
Protein shuchwe
-
10- order of amino acids
. Has peptide bonds
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27 alpha helix/beta pleated sheets. Has
hydrogen bonds
37 further .
folding Has
hydrogen bonds,
=
disulfide and ionic bonds
bridges
4- shuctves created from multiple
polypeptide chains
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A DNA , RNA and proteins are directional molecules , one end is different
than the other end
Types of RNA
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MRNA
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tRNA
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SiRNA
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MiRNA
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rRNA
regulatory RNAs
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