Rau’s Respiratory Care Pharmacology 11th Edition Test Bank by Douglas Gardenhire, ISBN 9780323871556, All 23 Chapters Covered, Verified Latest Edition

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Rau’s Respiratory Care Pharmacology
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11th Edition by Douglas Gardenhire,
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All Chapters 1 to 23 Covered
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, TABLEOFCONTENTS rt rt




Unit I: Basic Concepts and Principles in Pharmacology
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1. Introduction to RespiratoryCarePharmacology
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2. Principles of DrugAction
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3.Administration of Aerosolized Agents
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4. Calculating DrugDoses
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5. The Central and Peripheral Nervous Systems
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Unit II: Drugs Used to Treat the Respiratory System
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6.Adrenergic(Sympathomimetic)Bronchodilators
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7.Anticholinergic(Parasympatholytic)Bronchodilators
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8. Xanthines
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9. Mucus-Controlling Drug Therapy
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10. Surfactant Agents
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11. Cortico steriods in RespiratoryCare
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12. Nonsteroidal AntiasthmaAgents
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13. Aerosolized Anti infectiveAgents
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14. Antimicrobial Agents
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15. Cold and Cough Agents
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16. Selected Agents of PulmonaryValue
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17. Neonatal and PediatricAerosolized Drug Therapy
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Unit III: Critical Care, Cardiovascular, and Polysomnography Agents
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18. Skeletal Muscle Relaxants (Neuromuscular Blocking Agents)
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19. Diuretic Agents
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20. Drugs Affectingthe Central NervousSystem
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21. Vasopressors, Inotropes, and Anti arrythmicAgents
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22. DrugsAffectingCirculation: Antihypertensives,Antianginals, Anti thrombotics
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23. Sleep and Sleep Pharmacology
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,Chapter01:Introduction to RespiratoryCare Pharmacology
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MULTIPLE CHOICE rt




1. What is the name of the receptor sites that are located in the peripheral vasculature, the heart,
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r bronchial muscle, and bronchial blood vessels?
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a. Beta 2 receptors c. Alphareceptors
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b. Gammareceptors d. Beta 1 receptors rt rt rt r t rt rt




ANS: C r t




Alpha receptors are located in theperipheral vasculature, the heart, bronchial muscle, and
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r bronchial blood vessels.
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PTS: 1 rt r t




2. Whichreceptor siteresults in tachycardia, an increased potential for arrhythmias, and an
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r increased cardiac output?
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a. Beta 1 receptor c. Alpha receptor
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b. Beta 2 receptor d. Delta receptor
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ANS: A r t




Stimulation of the beta-1 receptors results in tachycardia, an increased potential for
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r arrhythmias, and an increased cardiac output. In administering drugs to the pulmonarysystem,
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r stimulation of the beta-1 sites is not desired. However, most respiratory pharmacologic agents
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r have some beta-1 stimulatory effect.
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PTS: 1 rt r t




3. Stimulation of the beta 2 receptors causes rt rt rt rt rt rt rt rt




a. peripheralvasoconstriction and mild bronchoconstriction inthelungs. rt rt rt rt rt rt rt




b. tachycardia,an increased potential for arrhythmias, and anincreased cardiacoutput. rt rt rt rt rt rt rt rt rt rt




c. bronchodilation.
d. peripheralvasodilation, bradycardia, and decreased cardiacoutput. rt rt rt rt rt rt




ANS: C r t




Stimulation of the beta-2 receptors in the lungs causes bronchodilation. rt rt rt rt rt rt rt rt rt




PTS: 1 rt r t




4. Acetylcholine stimulates rt r t rt




a. theVagus nerve. tr rt




b. theadrenergic receptors. rt rt




c. thesympathetic nervous system. rt rt rt




d. thecholinergic receptors. rt rt




ANS: D r t




Acetylcholinestimulates thecholinergic receptors. rt rt rt rt




PTS: 1 rt r t




5. What immunoglobulin antibodysensitizes the mast cell?
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a. Leukotrienes c. Histamine

, b. IgE d. Prostaglandins
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ANS: B r t




The IgE (reagin) antibodies sensitize the mast cell. Repeated exposure to the antigen causes the
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r degranulation of the mast cell.
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PTS: 1 rt r t




6. Whichof the following is caused byhistamine release fromthe mast cells?
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I. Bronchodilation
II. Increased bronchial gland secretion rt rt rt




III. Increased amount of mucus present in the airways rt rt rt rt rt rt rt




a. I and II only rt c. III only rt rt rt




b. II and III only rt d. I, II, III rt rt rt rt r t rt rt




ANS: B r t




Histamineis alsoapotent bronchoconstrictor.In additiontoitsbronchoconstrictiveactivity, histamine
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II) increases bronchial gland secretion, causing III) an increase in the amount of mucus
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r present in the airways. Histamine may also have an effect on vascular permeability similar to
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r the effect of- SRS-A.
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PTS: 1 rt r t




7. Asympathomimetic drug would cause
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a. bronchodilation. c. Histaminerelease. rt




b. bronchoconstriction. d. Vagus nerve stimulation.
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ANS: A r t




A sympathomimetic drug would cause bronchodilation. Sympathomimetic agents arethe drugs most
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r commonly used to reverse bronchospasm.
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PTS: 1 rt r t




8. Stimulation of the sympathetic nervous systemcauses rt rt rt rt rt rt rtrt




a. vascular permeability. c. bronchodilation. rt




b. decreased blood pressure. d. bronchoconstriction. rt rt rt r t




ANS: C r t




Sympatheticnervous systemstimulation causes bronchodilation. rt rt tr rt rt




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9. Whichof the following would NOTcause a bronchospasm or bronchoconstriction?
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a. Leukotrienes c. Histamine
b. Beta 1 receptors d. Prostaglandins rt rt rt r t




ANS: B r t




Beta-1 receptors would not cause a bronchospasm or bronchoconstriction. Leukotrienes
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rare one of many chemical mediators released by the mast cells. Leukotrienes cause a direct,
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rstrong bronchoconstriction. Histamine is also a potent bronchoconstrictor. Prostaglandins cause
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ra strong bronchospasm, especially in asthmatic patients.
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PTS: 1 rt r t