Immunology exam 2 study UAMS MLT-MLS
Study online at https://quizlet.com/_8udnwm
1. humoral: antigen recep- B cell receptor: antibody
tor
2. Humoral: Contact w/ anti- Bind AGN w/ surface antibody
gen
3. Humoral: Events af- Clone w/:Memory cells Plasma cells
terbinding w/ specific
antigen
4. Humoral: Function of ef- Plasma cell: Produces antibodies
fector cell
5. Cell mediated: Antigen T cell receptor (TCR)
receptor
6. Cell mediated: Contact w/ APCs present AGN w/inMHC molecules
antigen
7. Cell mediated: Events af- Clone w/:Memory cells Effector cell
terbinding w/ specific
antigen
8. Cell mediated: Function Th-Produces cytokines
of effector cell Tc-Kills altered cells
9. Origin of B cells: Hematopoietic stem cells
10. Where are B cells made? Bone marrow
11. What kind of lym- antigen-independent lymphopoiesis
phopoiesis does the B
cells have?
, Immunology exam 2 study UAMS MLT-MLS
Study online at https://quizlet.com/_8udnwm
12. With the maturation of Proliferation
lymphocytes, what are Expression
the 3 processes? Selection
13. What does Antigen-inde- It does not need an antigen to activate or replicate
pendent lymphopoiesis
mean?
14. What % of peripheral 10-15% of peripheral blood lymphocytes
blood lymphocytes are B
cells?
15. B cell CD marker CD19 Signaling to regulate B cell development & activation
16. B cell CD marker CD20 Thought to be involved in B cell activation
17. B cell CD marker CD21 Receptor for complement breakdown component
18. B cell CD marker CD25 Found on activated T & B cells; receptor for interleukin-2 (IL-2);it is a
growth factor made by T cells
19. B cell CD marker MHC II Found on B cells; Interact w/ Th cells (T-helper); present on all stages
except on plasma cell
can be an antigen presenting cell (APC) for a T-helper cell
20. B cell CD marker MHC I Found on all nucleated cells
21. B cell CD marker CD 45R Found on all hematopoietic cells; involved in activation
22. CD16 on NK cells binds Fc of IgG
23. CD56 unique marker for NK cells
24. What NKs CD marker CD56high
produces more cytokines
, Immunology exam 2 study UAMS MLT-MLS
Study online at https://quizlet.com/_8udnwm
and help support anti-
body production
25. What is a growth factor Interleukin-2
that is released by T cells?
26. What % of our B cells will around 90%
go thought apoptosis?
27. Progenitor B cell (Pro-B First recognizable cell in B-cell line
cell) Cell genes committed to formation of μ (mu); IgM heavy chain)
Bone marrow stromal cells produce cytokines
28. Preliminary B-Cell (Pre-B -μ heavy chains form and are found in cytoplasm
Cell) -Cell genes committed to formation of light chains (surrogate)
-μ heavy chains and surrogate light chains form Pre-B receptor to
stimulate PROLIFERATION & further MATURATION
29. Mature B Cell -will have a complete IgM and IgD antibody
-have to have both to recognize Antigen (ANG)
-Travels to secondary lymphoid organs
30. Immature B cell -Complete IgM molecule on cell surface
-Variable regions on heavy & light chains determine specificity
•μ no longer in cytoplasm
31. What is BCR? Co-expression of IgD and IgM
32. What is the process once -Cell genes committed to formation of IgD; involves recombination of
an Immature B cell is cre- heavy chains genes
ated? -Self-reacting B cells eliminated Apoptosis -cell self-destruction
-If they pass the test they can undergo further maturation in the
spleen
Study online at https://quizlet.com/_8udnwm
1. humoral: antigen recep- B cell receptor: antibody
tor
2. Humoral: Contact w/ anti- Bind AGN w/ surface antibody
gen
3. Humoral: Events af- Clone w/:Memory cells Plasma cells
terbinding w/ specific
antigen
4. Humoral: Function of ef- Plasma cell: Produces antibodies
fector cell
5. Cell mediated: Antigen T cell receptor (TCR)
receptor
6. Cell mediated: Contact w/ APCs present AGN w/inMHC molecules
antigen
7. Cell mediated: Events af- Clone w/:Memory cells Effector cell
terbinding w/ specific
antigen
8. Cell mediated: Function Th-Produces cytokines
of effector cell Tc-Kills altered cells
9. Origin of B cells: Hematopoietic stem cells
10. Where are B cells made? Bone marrow
11. What kind of lym- antigen-independent lymphopoiesis
phopoiesis does the B
cells have?
, Immunology exam 2 study UAMS MLT-MLS
Study online at https://quizlet.com/_8udnwm
12. With the maturation of Proliferation
lymphocytes, what are Expression
the 3 processes? Selection
13. What does Antigen-inde- It does not need an antigen to activate or replicate
pendent lymphopoiesis
mean?
14. What % of peripheral 10-15% of peripheral blood lymphocytes
blood lymphocytes are B
cells?
15. B cell CD marker CD19 Signaling to regulate B cell development & activation
16. B cell CD marker CD20 Thought to be involved in B cell activation
17. B cell CD marker CD21 Receptor for complement breakdown component
18. B cell CD marker CD25 Found on activated T & B cells; receptor for interleukin-2 (IL-2);it is a
growth factor made by T cells
19. B cell CD marker MHC II Found on B cells; Interact w/ Th cells (T-helper); present on all stages
except on plasma cell
can be an antigen presenting cell (APC) for a T-helper cell
20. B cell CD marker MHC I Found on all nucleated cells
21. B cell CD marker CD 45R Found on all hematopoietic cells; involved in activation
22. CD16 on NK cells binds Fc of IgG
23. CD56 unique marker for NK cells
24. What NKs CD marker CD56high
produces more cytokines
, Immunology exam 2 study UAMS MLT-MLS
Study online at https://quizlet.com/_8udnwm
and help support anti-
body production
25. What is a growth factor Interleukin-2
that is released by T cells?
26. What % of our B cells will around 90%
go thought apoptosis?
27. Progenitor B cell (Pro-B First recognizable cell in B-cell line
cell) Cell genes committed to formation of μ (mu); IgM heavy chain)
Bone marrow stromal cells produce cytokines
28. Preliminary B-Cell (Pre-B -μ heavy chains form and are found in cytoplasm
Cell) -Cell genes committed to formation of light chains (surrogate)
-μ heavy chains and surrogate light chains form Pre-B receptor to
stimulate PROLIFERATION & further MATURATION
29. Mature B Cell -will have a complete IgM and IgD antibody
-have to have both to recognize Antigen (ANG)
-Travels to secondary lymphoid organs
30. Immature B cell -Complete IgM molecule on cell surface
-Variable regions on heavy & light chains determine specificity
•μ no longer in cytoplasm
31. What is BCR? Co-expression of IgD and IgM
32. What is the process once -Cell genes committed to formation of IgD; involves recombination of
an Immature B cell is cre- heavy chains genes
ated? -Self-reacting B cells eliminated Apoptosis -cell self-destruction
-If they pass the test they can undergo further maturation in the
spleen
