NAPLEX Infectious Disease EXAM Questions AND Correct Answers
1st line for Aspergillosis? - ✔✔Voriconazole (Vfend)
1st line for Candida glabrata and krusei? - ✔✔Caspo/micafungin
1st line for Candida? - ✔✔Caspo/micafungin, Azoles
1st line for CMV? - ✔✔GANciclovir (zirgan), Foscarnet (foscavir), Valganciclovir
(valcyte)
1st line for HSV? - ✔✔acyclovir (zovirax), valacyclovir (valtrex), famciclovir
(famvir)
1st line for Mycobacterium avium complex (MAC)? - ✔✔Azithromycin weekly
1st line for PJP (PCP)? - ✔✔Bactrim
A patient has a CLcr < 60 mL/min, how do you adjust Tigecycline? - ✔✔you
don't, it doesn't require adjustment for renal impairment.
AE of FQs - ✔✔QT prolongation, cartilage/tendonitis (avoid in children and
pregnant women)
all B-lactams can decrease seizure threshold, but which B-lactam combo drug,
specifically, is thought to cause seizures? - ✔✔imipenem/cilastatin
, Aminopenicillins are what two drugs? They extensively cover gram ___ and the
common gram ____? - ✔✔amoxicillin and ampicillin, they have extended
coverage of gram + and some common gram - (e coli and h flu)
ANC equation - ✔✔ANC= (%bands + % segs) x WBC
Are carabapenems effective against anaerobes? - ✔✔yes
are doxy and minocycline affected by food? - ✔✔no
are FQs good for pseudomonas? - ✔✔yes, except moxi
are third generations more gram positive or negative active? - ✔✔gram
negative, also CSF penetration
can you give vancomycin IM? - ✔✔no, causes tissue necrosis
carbapenems are antipseudomonal except for ___? - ✔✔ertapenem (Invanz)
Cefepime is what generation cephalosporin? What is it active against? -
✔✔Fourth, Pseudomonas
describe vancomycin's coverage - ✔✔only gram +, including MRSA
1st line for Aspergillosis? - ✔✔Voriconazole (Vfend)
1st line for Candida glabrata and krusei? - ✔✔Caspo/micafungin
1st line for Candida? - ✔✔Caspo/micafungin, Azoles
1st line for CMV? - ✔✔GANciclovir (zirgan), Foscarnet (foscavir), Valganciclovir
(valcyte)
1st line for HSV? - ✔✔acyclovir (zovirax), valacyclovir (valtrex), famciclovir
(famvir)
1st line for Mycobacterium avium complex (MAC)? - ✔✔Azithromycin weekly
1st line for PJP (PCP)? - ✔✔Bactrim
A patient has a CLcr < 60 mL/min, how do you adjust Tigecycline? - ✔✔you
don't, it doesn't require adjustment for renal impairment.
AE of FQs - ✔✔QT prolongation, cartilage/tendonitis (avoid in children and
pregnant women)
all B-lactams can decrease seizure threshold, but which B-lactam combo drug,
specifically, is thought to cause seizures? - ✔✔imipenem/cilastatin
, Aminopenicillins are what two drugs? They extensively cover gram ___ and the
common gram ____? - ✔✔amoxicillin and ampicillin, they have extended
coverage of gram + and some common gram - (e coli and h flu)
ANC equation - ✔✔ANC= (%bands + % segs) x WBC
Are carabapenems effective against anaerobes? - ✔✔yes
are doxy and minocycline affected by food? - ✔✔no
are FQs good for pseudomonas? - ✔✔yes, except moxi
are third generations more gram positive or negative active? - ✔✔gram
negative, also CSF penetration
can you give vancomycin IM? - ✔✔no, causes tissue necrosis
carbapenems are antipseudomonal except for ___? - ✔✔ertapenem (Invanz)
Cefepime is what generation cephalosporin? What is it active against? -
✔✔Fourth, Pseudomonas
describe vancomycin's coverage - ✔✔only gram +, including MRSA
