TEST BANK FOR CLAYTON’S BASIC PHARMACOLOGY FOR
14 14 14 14 14 14
NURSES 19TH EDITION BY MICHELLE WILLIHNGANZ |
14 14 14 14 14 14 14
COMPLETE CHAPTERS 1-48 | 100%VERIFIED.
14 1 4 14 14 14
,Chapter 1: Drug Definitions, Standards, and Information Sources
14 14 14 14 14 14 14
Test Bank
14 14
MULTIPLE CHOICE 14
1. What is the name under which a drug is listed by the U.S. Food and Drug Administration
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
14 (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: 1 4 C
The official name is the name under which a drug is listed by the FDA. The brand name, or
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
trademark, is the name given to a drug by its manufacturer. The nonproprietary, or generic,
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
name is provided by the U.S. Adopted Names Council.
14 14 14 14 14 14 14 14 14
DIF: Cognitive Level: Knowledge REF: p. 1 OBJ: 14 14 1 4 14
1 2 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
1 4 14 14 14 14 14 14 14
2. Which source contains information specific to nutritional supplements?
14 14 14 14 14 14 14
a. USP Dictionary of USAN & International Drug Names
14 14 14 14 14 14 14
b. Natural Medicines Comprehensive Database 14 14 14
c. United States Pharmacopoeia/National Formulary (USP NF) 14 14 14 14 14
d. Drug Interaction Facts 14 14
ANS: 1 4 C
United States Pharmacopoeia/National Formulary contains information specific to nutritional
14 14 14 14 14 14 14 14
supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
14 14 14 14 14 14 14 14 14 14 14 14 14 14
names, pronunciation guide, and possible future FDA approved drugs; it does not include
14 14 14 14 14 14 14 14 14 14 14 14 14
nutritional supplements. Natural Medicines Comprehensive Database contains evidence based
14 14 14 14 14 14 14 14 14
information on herbal medicines and herbal combination products; it does not include
14 14 14 14 14 14 14 14 14 14 14 14
information specific to nutritional supplements. Drug Interaction Facts contains
14 14 14 14 14 14 14 14 14
comprehensive information on drug interaction facts; it does not include nutritional
14 14 14 14 14 14 14 14 14 14 14
supplements.
14
DIF: Cognitive Level: Knowledge REF: p. 2 14 14 1 4 14 OBJ:
1 4 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Physiological Integrity
1 4 14 14 14 14 14
3. What is the most comprehensive reference available to research a drug interaction?
14 14 14 14 14 14 14 14 14 14 14
a. Drug Facts and Comparisons 14 14 14
b. Drug Interaction Facts 14 14
c. Handbook on Injectable Drugs 14 14 14
d. Martindale—The Complete Drug Reference 14 14 14
ANS: 1 4 B
, Stuvia.com - The Marketplace to Buy and Sell your Study 14 14 14 14 14 14 14 14 14
Material
14
First published in 1983, Drug Interaction Facts is the most comprehensive book available on
14 14 14 14 14 14 14 14 14 14 14 14 14
drug interactions. In addition to monographs listing various aspects of drug interactions, this
14 14 14 14 14 14 14 14 14 14 14 14 14
information is reviewed and updated by an internationally renowned group of physicians and
14 14 14 14 14 14 14 14 14 14 14 14 14
pharmacists with clinical and scientific expertise.
14 14 14 14 14 14
DIF: Cognitive Level: Comprehension REF: p. 3 14 14 1 4 14 OBJ:
1 3 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Physiological Integrity
1 4 14 14 14 14 14
4. The physician has written an order for a drug with which the nurse is unfamiliar. Which
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
section of the Physicians’ Desk Reference (PDR) is most helpful to get information about this
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
drug?
14
a. Manufacturer’s section 14
b. Brand and Generic Name section 14 14 14 14
c. Product Category section 14 14
d. Product Information section 14 14
ANS: 1 4 B
A physician’s order would include the brand and/or generic name of the drug. The alphabetic
14 14 14 14 14 14 14 14 14 14 14 14 14 14
index in the PDR would make this section the most user friendly. Based on a physician’s order,
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
manufacturer’s information and classification information would not be known. The
14 14 14 14 14 14 14 14 14 14
Manufacturer’s section is a roster of manufacturers. The Product Category section lists
14 14 14 14 14 14 14 14 14 14 14 14
products subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and
14 14 14 14 14 14 14 14 14 14 14
antibiotics. The Product Information section contains reprints of the package inserts for the
14 14 14 14 14 14 14 14 14 14 14 14 14
major products of manufacturers.
14 14 14 14
DIF: Cognitive Level: Comprehension REF: p. 3 14 14 1 4 14 OBJ:
1 4 TOP: Nursing Process Step: Planning
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Physiological Integrity
1 4 14 14 14 14 14
5. Which online drug reference makes available to health care providers and the public a
14 14 14 14 14 14 14 14 14 14 14 14 14
14 standard, comprehensive, up to date look up and downloadable resource about medicines?
14 14 14 14 14 14 14 14 14 14 14
a. American Drug Index 14 14
b. American Hospital Formulary 14 14
c. DailyMed
d. Physicians’ Desk Reference (PDR) 14 14 14
ANS: 1 4 C
DailyMed makes available to health care providers and the public a standard, comprehensive, up
14 14 14 14 14 14 14 14 14 14 14 14 14
to date look up and downloadable resource about medicines. The American Drug Index is not
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
appropriate for patient use. The American Hospital Formulary is not appropriate for patient
14 14 14 14 14 14 14 14 14 14 14 14 14
use. The PDR is not appropriate for patient use.
14 14 14 14 14 14 14 14 14
DIF: Cognitive Level: Knowledge REF: p. 4 14 14 1 4 14 OBJ:
1 5 TOP: Nursing Process Step: Implementation
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Physiological Integrity
1 4 14 14 14 14 14
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
14 14 14 14 14 14 14 14 14 14 14 14 14 14
a. Federal Food, Drug, and Cosmetic Act (1938) 14 14 14 14 14 14
b. Durham Humphrey Amendment (1952) 14 14 14
c. Controlled Substances Act (1970) 14 14 14
19TH EDITION
14
Downloaded by: Ariah | 14 14 14 14
Distribution of this document is illegal 14 14 14 14 14
, Stuvia.com - The Marketplace to Buy and Sell your Study 14 14 14 14 14 14 14 14 14
Material
14
d. Kefauver Harris Drug Amendment (1962) 14 14 14 14
ANS: 1 4 A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
of all drugs before marketing. Later amendments and acts helped tighten FDA control and
14 14 14 14 14 14 14 14 14 14 14 14 14 14
ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot
14 14 14 14 14 14 14 14 14 14 14 14 14 14
be used safely without medical supervision and restricts their sale to prescription by a licensed
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
practitioner. The Controlled Substances Act addresses only controlled substances and their
14 14 14 14 14 14 14 14 14 14 14
categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug
14 14 14 14 14 14 14 14 14 14 14 14
safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
before marketing them.
14 14 14
DIF: Cognitive Level: Knowledge REF: p. 4 14 14 1 4 14 OBJ:
1 8 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Physiological Integrity
1 4 14 14 14 14 14
7. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological
14 14 14 14 14 14 14 14 14 14 14 14
14 dependency. Under which classification does this drug fall? 14 14 14 14 14 14 14
a. I
b. II
c. III
d. IV
ANS: 1 4 B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
14 14 14 14 14 14 14 14 14 14 14 14 14
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
lead to low to moderate physical dependence or high psychological dependence. Schedule IV
14 14 14 14 14 14 14 14 14 14 14 14 14
drugs have low potential for abuse. Use may lead to limited physical or psychological
14 14 14 14 14 14 14 14 14 14 14 14 14 14
dependence.
14
DIF: Cognitive Level: Comprehension REF: p. 4 | p. 5 OBJ: 14 14 1 4 14 14 14 14
1 7 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
1 4 14 14 14 14 14 14 14
8. What would the FDA do to expedite drug development and approval for an outbreak of
14 14 14 14 14 14 14 14 14 14 14 14 14 14
smallpox, for which there is no known treatment?
14 14 14 14 14 14 14 14
a. List smallpox as a health orphan disease. 14 14 14 14 14 14
b. Omit the preclinical research phase. 14 14 14 14
c. Extend the clinical research phase. 14 14 14 14
d. Fast track the investigational drug. 14 14 14 14
ANS: 1 4 D
Once the Investigational New Drug Application has been approved, the drug can receive
14 14 14 14 14 14 14 14 14 14 14 14
highest priority within the agency, which is called fast tracking. A smallpox outbreak would
14 14 14 14 14 14 14 14 14 14 14 14 14 14
become a priority concern in the world. Orphan diseases are not researched in a priority
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
manner. Preclinical research is not omitted. Extending any phase of the research would mean a
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
clinical research phase have been completed in a safe manner.
14 14 14 14 14 14 14 14 14 14
DIF: Cognitive Level: Knowledge REF: 14 14 1 4 p. 7 14 OBJ:
1 8 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
19TH EDITION
14
Downloaded by: Ariah | 14 14 14 14
Distribution of this document is illegal 14 14 14 14 14
14 14 14 14 14 14
NURSES 19TH EDITION BY MICHELLE WILLIHNGANZ |
14 14 14 14 14 14 14
COMPLETE CHAPTERS 1-48 | 100%VERIFIED.
14 1 4 14 14 14
,Chapter 1: Drug Definitions, Standards, and Information Sources
14 14 14 14 14 14 14
Test Bank
14 14
MULTIPLE CHOICE 14
1. What is the name under which a drug is listed by the U.S. Food and Drug Administration
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
14 (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: 1 4 C
The official name is the name under which a drug is listed by the FDA. The brand name, or
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
trademark, is the name given to a drug by its manufacturer. The nonproprietary, or generic,
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
name is provided by the U.S. Adopted Names Council.
14 14 14 14 14 14 14 14 14
DIF: Cognitive Level: Knowledge REF: p. 1 OBJ: 14 14 1 4 14
1 2 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
1 4 14 14 14 14 14 14 14
2. Which source contains information specific to nutritional supplements?
14 14 14 14 14 14 14
a. USP Dictionary of USAN & International Drug Names
14 14 14 14 14 14 14
b. Natural Medicines Comprehensive Database 14 14 14
c. United States Pharmacopoeia/National Formulary (USP NF) 14 14 14 14 14
d. Drug Interaction Facts 14 14
ANS: 1 4 C
United States Pharmacopoeia/National Formulary contains information specific to nutritional
14 14 14 14 14 14 14 14
supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
14 14 14 14 14 14 14 14 14 14 14 14 14 14
names, pronunciation guide, and possible future FDA approved drugs; it does not include
14 14 14 14 14 14 14 14 14 14 14 14 14
nutritional supplements. Natural Medicines Comprehensive Database contains evidence based
14 14 14 14 14 14 14 14 14
information on herbal medicines and herbal combination products; it does not include
14 14 14 14 14 14 14 14 14 14 14 14
information specific to nutritional supplements. Drug Interaction Facts contains
14 14 14 14 14 14 14 14 14
comprehensive information on drug interaction facts; it does not include nutritional
14 14 14 14 14 14 14 14 14 14 14
supplements.
14
DIF: Cognitive Level: Knowledge REF: p. 2 14 14 1 4 14 OBJ:
1 4 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Physiological Integrity
1 4 14 14 14 14 14
3. What is the most comprehensive reference available to research a drug interaction?
14 14 14 14 14 14 14 14 14 14 14
a. Drug Facts and Comparisons 14 14 14
b. Drug Interaction Facts 14 14
c. Handbook on Injectable Drugs 14 14 14
d. Martindale—The Complete Drug Reference 14 14 14
ANS: 1 4 B
, Stuvia.com - The Marketplace to Buy and Sell your Study 14 14 14 14 14 14 14 14 14
Material
14
First published in 1983, Drug Interaction Facts is the most comprehensive book available on
14 14 14 14 14 14 14 14 14 14 14 14 14
drug interactions. In addition to monographs listing various aspects of drug interactions, this
14 14 14 14 14 14 14 14 14 14 14 14 14
information is reviewed and updated by an internationally renowned group of physicians and
14 14 14 14 14 14 14 14 14 14 14 14 14
pharmacists with clinical and scientific expertise.
14 14 14 14 14 14
DIF: Cognitive Level: Comprehension REF: p. 3 14 14 1 4 14 OBJ:
1 3 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Physiological Integrity
1 4 14 14 14 14 14
4. The physician has written an order for a drug with which the nurse is unfamiliar. Which
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
section of the Physicians’ Desk Reference (PDR) is most helpful to get information about this
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
drug?
14
a. Manufacturer’s section 14
b. Brand and Generic Name section 14 14 14 14
c. Product Category section 14 14
d. Product Information section 14 14
ANS: 1 4 B
A physician’s order would include the brand and/or generic name of the drug. The alphabetic
14 14 14 14 14 14 14 14 14 14 14 14 14 14
index in the PDR would make this section the most user friendly. Based on a physician’s order,
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
manufacturer’s information and classification information would not be known. The
14 14 14 14 14 14 14 14 14 14
Manufacturer’s section is a roster of manufacturers. The Product Category section lists
14 14 14 14 14 14 14 14 14 14 14 14
products subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and
14 14 14 14 14 14 14 14 14 14 14
antibiotics. The Product Information section contains reprints of the package inserts for the
14 14 14 14 14 14 14 14 14 14 14 14 14
major products of manufacturers.
14 14 14 14
DIF: Cognitive Level: Comprehension REF: p. 3 14 14 1 4 14 OBJ:
1 4 TOP: Nursing Process Step: Planning
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Physiological Integrity
1 4 14 14 14 14 14
5. Which online drug reference makes available to health care providers and the public a
14 14 14 14 14 14 14 14 14 14 14 14 14
14 standard, comprehensive, up to date look up and downloadable resource about medicines?
14 14 14 14 14 14 14 14 14 14 14
a. American Drug Index 14 14
b. American Hospital Formulary 14 14
c. DailyMed
d. Physicians’ Desk Reference (PDR) 14 14 14
ANS: 1 4 C
DailyMed makes available to health care providers and the public a standard, comprehensive, up
14 14 14 14 14 14 14 14 14 14 14 14 14
to date look up and downloadable resource about medicines. The American Drug Index is not
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
appropriate for patient use. The American Hospital Formulary is not appropriate for patient
14 14 14 14 14 14 14 14 14 14 14 14 14
use. The PDR is not appropriate for patient use.
14 14 14 14 14 14 14 14 14
DIF: Cognitive Level: Knowledge REF: p. 4 14 14 1 4 14 OBJ:
1 5 TOP: Nursing Process Step: Implementation
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Physiological Integrity
1 4 14 14 14 14 14
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
14 14 14 14 14 14 14 14 14 14 14 14 14 14
a. Federal Food, Drug, and Cosmetic Act (1938) 14 14 14 14 14 14
b. Durham Humphrey Amendment (1952) 14 14 14
c. Controlled Substances Act (1970) 14 14 14
19TH EDITION
14
Downloaded by: Ariah | 14 14 14 14
Distribution of this document is illegal 14 14 14 14 14
, Stuvia.com - The Marketplace to Buy and Sell your Study 14 14 14 14 14 14 14 14 14
Material
14
d. Kefauver Harris Drug Amendment (1962) 14 14 14 14
ANS: 1 4 A
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
of all drugs before marketing. Later amendments and acts helped tighten FDA control and
14 14 14 14 14 14 14 14 14 14 14 14 14 14
ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot
14 14 14 14 14 14 14 14 14 14 14 14 14 14
be used safely without medical supervision and restricts their sale to prescription by a licensed
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
practitioner. The Controlled Substances Act addresses only controlled substances and their
14 14 14 14 14 14 14 14 14 14 14
categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug
14 14 14 14 14 14 14 14 14 14 14 14
safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
before marketing them.
14 14 14
DIF: Cognitive Level: Knowledge REF: p. 4 14 14 1 4 14 OBJ:
1 8 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Physiological Integrity
1 4 14 14 14 14 14
7. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological
14 14 14 14 14 14 14 14 14 14 14 14
14 dependency. Under which classification does this drug fall? 14 14 14 14 14 14 14
a. I
b. II
c. III
d. IV
ANS: 1 4 B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
severe psychological and physical dependence. Schedule I drugs have high potential for abuse
14 14 14 14 14 14 14 14 14 14 14 14 14
and no recognized medical use. Schedule III drugs have some potential for abuse. Use may
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
lead to low to moderate physical dependence or high psychological dependence. Schedule IV
14 14 14 14 14 14 14 14 14 14 14 14 14
drugs have low potential for abuse. Use may lead to limited physical or psychological
14 14 14 14 14 14 14 14 14 14 14 14 14 14
dependence.
14
DIF: Cognitive Level: Comprehension REF: p. 4 | p. 5 OBJ: 14 14 1 4 14 14 14 14
1 7 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
MSC: NCLEX Client Needs Category: Safe, Effective Care Environment
1 4 14 14 14 14 14 14 14
8. What would the FDA do to expedite drug development and approval for an outbreak of
14 14 14 14 14 14 14 14 14 14 14 14 14 14
smallpox, for which there is no known treatment?
14 14 14 14 14 14 14 14
a. List smallpox as a health orphan disease. 14 14 14 14 14 14
b. Omit the preclinical research phase. 14 14 14 14
c. Extend the clinical research phase. 14 14 14 14
d. Fast track the investigational drug. 14 14 14 14
ANS: 1 4 D
Once the Investigational New Drug Application has been approved, the drug can receive
14 14 14 14 14 14 14 14 14 14 14 14
highest priority within the agency, which is called fast tracking. A smallpox outbreak would
14 14 14 14 14 14 14 14 14 14 14 14 14 14
become a priority concern in the world. Orphan diseases are not researched in a priority
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
manner. Preclinical research is not omitted. Extending any phase of the research would mean a
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14 14
clinical research phase have been completed in a safe manner.
14 14 14 14 14 14 14 14 14 14
DIF: Cognitive Level: Knowledge REF: 14 14 1 4 p. 7 14 OBJ:
1 8 TOP: Nursing Process Step: Assessment
4 14 1 4 14 14 14
19TH EDITION
14
Downloaded by: Ariah | 14 14 14 14
Distribution of this document is illegal 14 14 14 14 14
