CWS Exam Prep questions with 100%
correct answers rated A+
1. Cadherins
2. Immunoglobulin Superfamily (IGSF)
3. Selectins
4. Integrins
5. Mucins
Integrins allow cells to interact with the surrounding environment or components of the ECM. -
correct answer ✔✔ Name the five types of Cell Adhesion Molecules? Which type enables cells
to detect and interact with components of the extracellular matrix?
Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale (germinativa) - correct answer ✔✔ What are the layers of the epidermis from
most superficial to most deep?
Papillary dermis
Reticular dermis - correct answer ✔✔ What are the layers of the dermis from most superficial
to most deep?
Langerhan's cells - correct answer ✔✔ What is/are the primary cell type(s) of the stratum
spinosum?
,Keratinocytes, Melanocytes, Merkel cells - correct answer ✔✔ What is/are the primary cell
type(s) of the stratum basale?
Corneocytes (terminally differentiated keratinocytes) - correct answer ✔✔ What is/are the
primary cell type(s) of the stratum granulosum?
Dead keratinocytes - correct answer ✔✔ What is/are the primary cell type(s) of the stratum
corneum?
Fibroblasts, Mast cells, Macrophages, Lymphocytes - correct answer ✔✔ What is/are the
primary cell type(s) of the dermis?
Superficial - correct answer ✔✔ Tissue loss includes only the epidermis.
Partial thickness - correct answer ✔✔ Tissue loss includes the epidermis and part of the dermis.
Full thickness - correct answer ✔✔ Tissue loss includes the epidermis and all of the dermis.
Subdermal - correct answer ✔✔ Tissue loss includes subcutaneous tissues.
Immediately after tissue injury - correct answer ✔✔ When does hemostasis or coagulation
occur during the stages of healing?
0-4 days - correct answer ✔✔ When does inflammation occur during the stages of healing?
4-21 days - correct answer ✔✔ When does proliferation occur during the stages of healing?
,Up to 2 years - correct answer ✔✔ How long can remodeling last?
Platelets - correct answer ✔✔ What are the key cells of hemostasis?
Neutrophils, Macrophages - correct answer ✔✔ What are the key cells of inflammation?
Fibroblasts, Epithelial cells, Endothelial cells, Macrophages - correct answer ✔✔ What are the
key cells of proliferation?
Fibroblasts - correct answer ✔✔ What are the key cells of remodeling?
Platelets and macrophages - correct answer ✔✔ What produces PDGF?
Platelet Derived Growth Factor - correct answer ✔✔ What stimulates fibroblasts?
A cell surface receptor that enables cells to interact with components of the ECM - correct
answer ✔✔ What is an integrin?
Keratinocytes and fibroblasts - correct answer ✔✔ What secretes MMPs and TIMPs?
TIMPs - correct answer ✔✔ What regulates the activity of MMPs?
Collagen
Elastin
Reticulin
Proteoglycans
, Glycosaminoglycans - correct answer ✔✔ Fibroblasts play a key role in the extracellular matrix
deposition of which types of proteins?
Type I - correct answer ✔✔ Myofibroblasts secrete which type of collagen?
Type I - correct answer ✔✔ Which type of collagen is primarily found in uninjured tissue?
Type III - correct answer ✔✔ Which type of collagen is primarily found in wounds in the
proliferative phase of wound healing?
Macrophage migration into the wound site - correct answer ✔✔ What is the transitional marker
between the inflammatory and proliferative phases of healing?
T lymphocytes - correct answer ✔✔ Which cells are the last to arrive during the proliferative
phase?
1. Cytotoxic T cells = directly target and kill any antigen-bearing cells
2. Helper T cells = activate macrophages and B lymphocytes
3. Suppressor T cells = down regulate inflammation and proliferation as the wound reaches
maturity - correct answer ✔✔ What are the three types of T lymphocytes and what are their
functions?
Neutrophils (PMN leukocytes) - correct answer ✔✔ What is considered the "first line of
defense" in wound healing?
1. Histamine
2. Heparin
3. Eicosanoids
correct answers rated A+
1. Cadherins
2. Immunoglobulin Superfamily (IGSF)
3. Selectins
4. Integrins
5. Mucins
Integrins allow cells to interact with the surrounding environment or components of the ECM. -
correct answer ✔✔ Name the five types of Cell Adhesion Molecules? Which type enables cells
to detect and interact with components of the extracellular matrix?
Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale (germinativa) - correct answer ✔✔ What are the layers of the epidermis from
most superficial to most deep?
Papillary dermis
Reticular dermis - correct answer ✔✔ What are the layers of the dermis from most superficial
to most deep?
Langerhan's cells - correct answer ✔✔ What is/are the primary cell type(s) of the stratum
spinosum?
,Keratinocytes, Melanocytes, Merkel cells - correct answer ✔✔ What is/are the primary cell
type(s) of the stratum basale?
Corneocytes (terminally differentiated keratinocytes) - correct answer ✔✔ What is/are the
primary cell type(s) of the stratum granulosum?
Dead keratinocytes - correct answer ✔✔ What is/are the primary cell type(s) of the stratum
corneum?
Fibroblasts, Mast cells, Macrophages, Lymphocytes - correct answer ✔✔ What is/are the
primary cell type(s) of the dermis?
Superficial - correct answer ✔✔ Tissue loss includes only the epidermis.
Partial thickness - correct answer ✔✔ Tissue loss includes the epidermis and part of the dermis.
Full thickness - correct answer ✔✔ Tissue loss includes the epidermis and all of the dermis.
Subdermal - correct answer ✔✔ Tissue loss includes subcutaneous tissues.
Immediately after tissue injury - correct answer ✔✔ When does hemostasis or coagulation
occur during the stages of healing?
0-4 days - correct answer ✔✔ When does inflammation occur during the stages of healing?
4-21 days - correct answer ✔✔ When does proliferation occur during the stages of healing?
,Up to 2 years - correct answer ✔✔ How long can remodeling last?
Platelets - correct answer ✔✔ What are the key cells of hemostasis?
Neutrophils, Macrophages - correct answer ✔✔ What are the key cells of inflammation?
Fibroblasts, Epithelial cells, Endothelial cells, Macrophages - correct answer ✔✔ What are the
key cells of proliferation?
Fibroblasts - correct answer ✔✔ What are the key cells of remodeling?
Platelets and macrophages - correct answer ✔✔ What produces PDGF?
Platelet Derived Growth Factor - correct answer ✔✔ What stimulates fibroblasts?
A cell surface receptor that enables cells to interact with components of the ECM - correct
answer ✔✔ What is an integrin?
Keratinocytes and fibroblasts - correct answer ✔✔ What secretes MMPs and TIMPs?
TIMPs - correct answer ✔✔ What regulates the activity of MMPs?
Collagen
Elastin
Reticulin
Proteoglycans
, Glycosaminoglycans - correct answer ✔✔ Fibroblasts play a key role in the extracellular matrix
deposition of which types of proteins?
Type I - correct answer ✔✔ Myofibroblasts secrete which type of collagen?
Type I - correct answer ✔✔ Which type of collagen is primarily found in uninjured tissue?
Type III - correct answer ✔✔ Which type of collagen is primarily found in wounds in the
proliferative phase of wound healing?
Macrophage migration into the wound site - correct answer ✔✔ What is the transitional marker
between the inflammatory and proliferative phases of healing?
T lymphocytes - correct answer ✔✔ Which cells are the last to arrive during the proliferative
phase?
1. Cytotoxic T cells = directly target and kill any antigen-bearing cells
2. Helper T cells = activate macrophages and B lymphocytes
3. Suppressor T cells = down regulate inflammation and proliferation as the wound reaches
maturity - correct answer ✔✔ What are the three types of T lymphocytes and what are their
functions?
Neutrophils (PMN leukocytes) - correct answer ✔✔ What is considered the "first line of
defense" in wound healing?
1. Histamine
2. Heparin
3. Eicosanoids
