APMLE Biochemistry Rapid Review Exam 2026 Questions and Answers

APMLE Biochemistry Rapid Review
Exam 2026 Questions and Answers

Rate determining Step of glycolysis - Correct answer-Phosphofructokinase-1

(PFK-1)

Rate determining Step of gluconeogenesis - Correct answer-Fructose-1,6-

bisphosphatase

Rate determining Step of TCA (Krebs) - Correct answer-Isocitrate Dehydrogenase

Rate determining Step of glycogenesis - Correct answer-glycogen synthase

Rate determining Step of of glycogenolysis - Correct answer-glycogen

phosphorylase

Rate determining Step of HMP Shunt - Correct answer-G6PD (glucose-6-

phosphate dehydrogenase)

Rate determining Step of De Novo Pyrimidine Synthesis - Correct answer-

Carbamoyl Phosphate Synthase II




©COPYRIGHT 2025, ALL RIGHTS RESERVED 1

, Rate determining Step of De Novo PURINE Synthesis - Correct answer-

Glutamine-phosphoribosylpyrophosphate (PRPP) amidotransferase

Rate determining Step of Urea Cycle - Correct answer-Carbamoyl phosphate

synthetase I

Rate determining Step of Fatty Acid Synthesis - Correct answer-Acetyl CoA

carboxylase

Rate determining Step of fatty acid oxidation - Correct answer-Carnitine

acyltransferase I

Rate determining Step of ketogenesis - Correct answer-HMG-CoA synthase

Rate determining Step of cholesterol synthesis - Correct answer-HMG-CoA

reductase

Irreversible Steps of the Krebs cycle - Correct answer-Citrate Synthase

IsoCitrate Dehydrogenase

Alpha-KG dehydrogenase

Name the essential amino acids - Correct answer-PVT TIM HaLL

Phenylalanine

Valine


©COPYRIGHT 2025, ALL RIGHTS RESERVED 2