APMLE Pharm - Cardiac/Renal Agents
Exam 2026 Questions and Answers
This drug has a SE called 'cinchonism' - Correct answer-Quinidine
3. This is the most common non-cardiac side effect of Quinidine - Correct answer-
Dirrahea
6. What drug will induce hypotension from ganglionic block with rapid IV
administration - Correct answer-Procainamide
7. This drug has an active metabolite called NAPA - Correct answer-Procainamide
9. This class IB is NOT effective against atrial arrhythmias - Correct answer-
Lidocaine
11. This drug is used to treat digoxin-induced arrhythmias. - Correct answer-
Phenytoin
13. This class IB drug is given slow IV to avoid arrhythmias or seizures - Correct
answer-Lidocaine
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,This drug is used orally to treat chronic ventricular arrhythmias - Correct answer-
Mexilitine
This class 1c drug has BB activity and is metabolized by CYP2D6 - Correct
answer-Propafenone
This beta blocker is rapidly metabolized by plasma esterase - Correct answer-
Esmolol
This drug contains Iodine - Correct answer-amiodarone
This is given IV for life threatening V-tach or V-fib. - Correct answer-Bretylium
This drug causes constipation and may make patients perform the valsalva while
pooping - Correct answer-Verapamil
This drug is used to treat A-Fib, A-Flutter and CHF, its antiarrhythmic mechanisms
are vagomimetic with direct inhibition of sympathetic activity - Correct answer-
Digoxin
Hyperkalemia increases the risk of _______ toxicity and Torsades de pointes. -
Correct answer-Digoxin
Be careful when using Digoxin with the following drug class due to hypokalemia -
Correct answer-Diuretic
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, Name the 2 treatments for Digoxin toxicity. - Correct answer-IV potasium and
FAB (digibind)
This has an antimuscarinic effect and is given for bradyarrythmias - Correct
answer-Atropine
This is given for PSVT (paroxysmal supraventricular tachycardia) and reentry.
Very short HL - Correct answer-Adenosine
Adenosine is antagonized by what class of molecules? - Correct answer-
Methylxanthines
Name the 3 loop diuretics - Correct answer-Loop, Thiaide, K sparing
Loop diuretics act on the: - Correct answer-Asc. loop on Henle
Thiazides act on - Correct answer-Distule tubule
Constipation is a major SE of this Alpha 2A agonist - Correct answer-Clonidine
This drug inhibits ejaculation - Correct answer-Clonidine
This drug must be discontinued slowly to avoid rebound sympathetic activity that
can cause hypertensive crisis, tachycardia or arrhythmia. - Correct answer-
Clonodine
©COPYRIGHT 2025, ALL RIGHTS RESERVED 3
Exam 2026 Questions and Answers
This drug has a SE called 'cinchonism' - Correct answer-Quinidine
3. This is the most common non-cardiac side effect of Quinidine - Correct answer-
Dirrahea
6. What drug will induce hypotension from ganglionic block with rapid IV
administration - Correct answer-Procainamide
7. This drug has an active metabolite called NAPA - Correct answer-Procainamide
9. This class IB is NOT effective against atrial arrhythmias - Correct answer-
Lidocaine
11. This drug is used to treat digoxin-induced arrhythmias. - Correct answer-
Phenytoin
13. This class IB drug is given slow IV to avoid arrhythmias or seizures - Correct
answer-Lidocaine
©COPYRIGHT 2025, ALL RIGHTS RESERVED 1
,This drug is used orally to treat chronic ventricular arrhythmias - Correct answer-
Mexilitine
This class 1c drug has BB activity and is metabolized by CYP2D6 - Correct
answer-Propafenone
This beta blocker is rapidly metabolized by plasma esterase - Correct answer-
Esmolol
This drug contains Iodine - Correct answer-amiodarone
This is given IV for life threatening V-tach or V-fib. - Correct answer-Bretylium
This drug causes constipation and may make patients perform the valsalva while
pooping - Correct answer-Verapamil
This drug is used to treat A-Fib, A-Flutter and CHF, its antiarrhythmic mechanisms
are vagomimetic with direct inhibition of sympathetic activity - Correct answer-
Digoxin
Hyperkalemia increases the risk of _______ toxicity and Torsades de pointes. -
Correct answer-Digoxin
Be careful when using Digoxin with the following drug class due to hypokalemia -
Correct answer-Diuretic
©COPYRIGHT 2025, ALL RIGHTS RESERVED 2
, Name the 2 treatments for Digoxin toxicity. - Correct answer-IV potasium and
FAB (digibind)
This has an antimuscarinic effect and is given for bradyarrythmias - Correct
answer-Atropine
This is given for PSVT (paroxysmal supraventricular tachycardia) and reentry.
Very short HL - Correct answer-Adenosine
Adenosine is antagonized by what class of molecules? - Correct answer-
Methylxanthines
Name the 3 loop diuretics - Correct answer-Loop, Thiaide, K sparing
Loop diuretics act on the: - Correct answer-Asc. loop on Henle
Thiazides act on - Correct answer-Distule tubule
Constipation is a major SE of this Alpha 2A agonist - Correct answer-Clonidine
This drug inhibits ejaculation - Correct answer-Clonidine
This drug must be discontinued slowly to avoid rebound sympathetic activity that
can cause hypertensive crisis, tachycardia or arrhythmia. - Correct answer-
Clonodine
©COPYRIGHT 2025, ALL RIGHTS RESERVED 3
