Study guide exam one units 1
Principles Of Pharmacology (Galen College of
Nursing)
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Study guide exam one
units 1-3 Unit one
Week one
pharmacology
Pharmacokinetics and Pharmacodynamics
Week one notes
Pharmacodynamics- what the drug does to the body
What effect does the drug have on the person you are giving it to
Pharmacokinetics- Pharmaco (drug) kinetics (movement)
- What does the body do to the drug
Pharmacokinetics has 4 phase
AD-ME – Absorption, distribution, metabolism, excretion
A-Absorption
Drug moves from site of absorption (small intestine) into the
bloodstream
Bioavailability – how much of the drug reaches the blood
stream
Factors affecting absorption
1.Circulation
- Poor blood flow to the GI tract and you taking oral med will lead
to a decrease in the rate of absorption
- Happens in pt. in shock or vasoconstricting drugs
2. Pain, stress, exercise
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- Blood gets shunted away from the gut.
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