lOMoAR cPSD| 6353920
Test bank Brenner and Stevens’ Pharmacology 5th Edition
BRENNER AND STEVENS’ PHARMACOLOGY 6TH EDITION TEST BANK
Chapter 1 Introduction to Pharmacology
A nurse working in radiology administers iodine to a patient who is having a
computed tomography (CT) scan. The nurse working on the oncology unit
administers chemotherapy to patients who have cancer. At the Public Health
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a
14-month-old child as a routine immunization. Which branch of pharmacology
1. best describes the actions of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are
involved with clinical pharmacology or pharmacotherapeutics, which is a branch
of pharmacology that deals with the uses of drugs to treat, prevent, and diagnose
disease. The radiology nurse is administering a drug to help diagnose a disease.
The oncology nurse is administering a drug to help treat a disease.
Pharmacoeconomics includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and pharmacokinetics is
how the body acts on the body.
A physician has ordered intramuscular (IM) injections of morphine, a narcotic,
every 4 hours as needed for pain in a motor vehicle accident victim. The nurse is
aware this drug has a high abuse potential. Under what category would morphine
2. be classified?
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
Ans: B
Feedback:
, lOMoAR cPSD| 6353920
Narcotics with a high abuse potential are classified as Schedule II drugs because
of severe dependence liability. Schedule I drugs have high abuse potential and no
accepted medical use. Schedule III drugs have a lesser abuse potential than II and
an accepted medical use. Schedule IV drugs have low abuse potential and limited
dependence liability.
When involved in phase III drug evaluation studies, what responsibilities would
3. the nurse have?
A) Working with animals who are given experimental drugs
B) Choosing appropriate patients to be involved in the drug study
C) Monitoring and observing patients closely for adverse effects
D) Conducting research to determine effectiveness of the drug
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which
patients are asked to record any symptoms they experience while taking the
drugs. Nurses may be responsible for helping collect and analyze the information
to be shared with the Food and Drug Administration (FDA) but would not
conduct research independently because nurses do not prescribe medications. Use
of animals in drug testing is done in the preclinical trials. Select patients who are
involved in phase II studies to participate in studies where the participants have
the disease the drug is intended to treat. These patients are monitored closely for
drug action and adverse effects. Phase I studies involve healthy human volunteers
who are usually paid for their participation. Nurses may observe for adverse
effects and toxicity.
What concept is considered when generic drugs are substituted for brand name
4. drugs?
A) Bioavailability
B) Critical concentration
C) Distribution
D) Half-life
Ans: A
Feedback:
, lOMoAR cPSD| 6353920
Bioavailability is the portion of a dose of a drug that reaches the systemic
circulation and is available to act on body cells. Binders used in a generic drug
may not be the same as those used in the brand name drug. Therefore, the way the
body breaks down and uses the drug may differ, which may eliminate a generic
drug substitution. Critical concentration is the amount of a drug that is needed to
cause a therapeutic effect and should not differ between generic and brand name
medications. Distribution is the phase of pharmacokinetics, which involves the
movement of a drug to the bodys tissues and is the same in generic and brand
name drugs. A drugs half-life is the time it takes for the amount of drug to
decrease to half the peak level, which should not change when substituting a
generic medication.
A nurse is assessing the patients home medication use. After listening to the
5. patient list current medications, the nurse asks what priority question?
A) Do you take any generic medications?
B) Are any of these medications orphan drugs?
C) Are these medications safe to take during pregnancy?
D) Do you take any over-the-counter medications?
Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-counter
medications because patients may not consider them important. The patient is
unlikely to know the meaning of orphan drugs unless they too are health care
providers. Safety during pregnancy, use of a generic medication, or classification
of orphan drugs are things the patient would be unable to answer but could be
found in reference books if the nurse wishes to research them.
After completing a course on pharmacology for nurses, what will the nurse
6. know?
A) Everything necessary for safe and effective medication administration
Current pharmacologic therapy; the nurse will not require ongoing
B) education for 5 years.
General drug information; the nurse can consult a drug guide for specific
C) drug information.
D) The drug actions that are associated with each classification of medication
Ans: C
, lOMoAR cPSD| 6353920
Feedback:
After completing a pharmacology course nurses will have general drug
information needed for safe and effective medication administration but will need
to consult a drug guide for specific drug information before administering any
medication. Pharmacology is constantly changing, with new drugs entering the
market and new uses for existing drugs identified. Continuing education in
pharmacology is essential to safe practice. Nurses tend to become familiar with
the medications they administer most often, but there will always be a need to
research new drugs and also those the nurse is not familiar with because no nurse
knows all medications.
A nurse is instructing a pregnant patient concerning the potential risk to her fetus
7. from a Pregnancy Category B drug. What would the nurse inform the patient?
Adequate studies in pregnant women have demonstrated there is no risk to
A) the fetus.
Animal studies have not demonstrated a risk to the fetus, but there have
B) been no adequate studies in pregnant women.
Animal studies have shown an adverse effect on the fetus, but there are no
C) adequate studies in pregnant women.
There is evidence of human fetal risk, but the potential benefits from use of
D) the drug may be acceptable despite potential risks.
Ans: B
Feedback:
Category B indicates that animal studies have not demonstrated a risk to the fetus.
However, there have not been adequate studies in pregnant women to
demonstrate risk to a fetus during the first trimester of pregnancy and no evidence
of risk in later trimesters. Category A indicates that adequate studies in pregnant
women have not demonstrated a risk to the fetus in the first trimester or in later
trimesters. Category C indicates that animal studies have shown an adverse effect
on the fetus, but no adequate studies in humans. Category D reveals evidence of
human fetal risk, but the potential benefits from the use of the drugs in pregnant
women may outweigh potential risks.
Discharge planning for patients leaving the hospital should include instructions
on the use of over-the-counter (OTC) drugs. Which comment by the patient
8. would demonstrate a good understanding of OTC drugs?
A) OTC drugs are safe and do not cause adverse effects if taken properly.
Test bank Brenner and Stevens’ Pharmacology 5th Edition
BRENNER AND STEVENS’ PHARMACOLOGY 6TH EDITION TEST BANK
Chapter 1 Introduction to Pharmacology
A nurse working in radiology administers iodine to a patient who is having a
computed tomography (CT) scan. The nurse working on the oncology unit
administers chemotherapy to patients who have cancer. At the Public Health
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a
14-month-old child as a routine immunization. Which branch of pharmacology
1. best describes the actions of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are
involved with clinical pharmacology or pharmacotherapeutics, which is a branch
of pharmacology that deals with the uses of drugs to treat, prevent, and diagnose
disease. The radiology nurse is administering a drug to help diagnose a disease.
The oncology nurse is administering a drug to help treat a disease.
Pharmacoeconomics includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and pharmacokinetics is
how the body acts on the body.
A physician has ordered intramuscular (IM) injections of morphine, a narcotic,
every 4 hours as needed for pain in a motor vehicle accident victim. The nurse is
aware this drug has a high abuse potential. Under what category would morphine
2. be classified?
A) Schedule I
B) Schedule II
C) Schedule III
D) Schedule IV
Ans: B
Feedback:
, lOMoAR cPSD| 6353920
Narcotics with a high abuse potential are classified as Schedule II drugs because
of severe dependence liability. Schedule I drugs have high abuse potential and no
accepted medical use. Schedule III drugs have a lesser abuse potential than II and
an accepted medical use. Schedule IV drugs have low abuse potential and limited
dependence liability.
When involved in phase III drug evaluation studies, what responsibilities would
3. the nurse have?
A) Working with animals who are given experimental drugs
B) Choosing appropriate patients to be involved in the drug study
C) Monitoring and observing patients closely for adverse effects
D) Conducting research to determine effectiveness of the drug
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which
patients are asked to record any symptoms they experience while taking the
drugs. Nurses may be responsible for helping collect and analyze the information
to be shared with the Food and Drug Administration (FDA) but would not
conduct research independently because nurses do not prescribe medications. Use
of animals in drug testing is done in the preclinical trials. Select patients who are
involved in phase II studies to participate in studies where the participants have
the disease the drug is intended to treat. These patients are monitored closely for
drug action and adverse effects. Phase I studies involve healthy human volunteers
who are usually paid for their participation. Nurses may observe for adverse
effects and toxicity.
What concept is considered when generic drugs are substituted for brand name
4. drugs?
A) Bioavailability
B) Critical concentration
C) Distribution
D) Half-life
Ans: A
Feedback:
, lOMoAR cPSD| 6353920
Bioavailability is the portion of a dose of a drug that reaches the systemic
circulation and is available to act on body cells. Binders used in a generic drug
may not be the same as those used in the brand name drug. Therefore, the way the
body breaks down and uses the drug may differ, which may eliminate a generic
drug substitution. Critical concentration is the amount of a drug that is needed to
cause a therapeutic effect and should not differ between generic and brand name
medications. Distribution is the phase of pharmacokinetics, which involves the
movement of a drug to the bodys tissues and is the same in generic and brand
name drugs. A drugs half-life is the time it takes for the amount of drug to
decrease to half the peak level, which should not change when substituting a
generic medication.
A nurse is assessing the patients home medication use. After listening to the
5. patient list current medications, the nurse asks what priority question?
A) Do you take any generic medications?
B) Are any of these medications orphan drugs?
C) Are these medications safe to take during pregnancy?
D) Do you take any over-the-counter medications?
Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-counter
medications because patients may not consider them important. The patient is
unlikely to know the meaning of orphan drugs unless they too are health care
providers. Safety during pregnancy, use of a generic medication, or classification
of orphan drugs are things the patient would be unable to answer but could be
found in reference books if the nurse wishes to research them.
After completing a course on pharmacology for nurses, what will the nurse
6. know?
A) Everything necessary for safe and effective medication administration
Current pharmacologic therapy; the nurse will not require ongoing
B) education for 5 years.
General drug information; the nurse can consult a drug guide for specific
C) drug information.
D) The drug actions that are associated with each classification of medication
Ans: C
, lOMoAR cPSD| 6353920
Feedback:
After completing a pharmacology course nurses will have general drug
information needed for safe and effective medication administration but will need
to consult a drug guide for specific drug information before administering any
medication. Pharmacology is constantly changing, with new drugs entering the
market and new uses for existing drugs identified. Continuing education in
pharmacology is essential to safe practice. Nurses tend to become familiar with
the medications they administer most often, but there will always be a need to
research new drugs and also those the nurse is not familiar with because no nurse
knows all medications.
A nurse is instructing a pregnant patient concerning the potential risk to her fetus
7. from a Pregnancy Category B drug. What would the nurse inform the patient?
Adequate studies in pregnant women have demonstrated there is no risk to
A) the fetus.
Animal studies have not demonstrated a risk to the fetus, but there have
B) been no adequate studies in pregnant women.
Animal studies have shown an adverse effect on the fetus, but there are no
C) adequate studies in pregnant women.
There is evidence of human fetal risk, but the potential benefits from use of
D) the drug may be acceptable despite potential risks.
Ans: B
Feedback:
Category B indicates that animal studies have not demonstrated a risk to the fetus.
However, there have not been adequate studies in pregnant women to
demonstrate risk to a fetus during the first trimester of pregnancy and no evidence
of risk in later trimesters. Category A indicates that adequate studies in pregnant
women have not demonstrated a risk to the fetus in the first trimester or in later
trimesters. Category C indicates that animal studies have shown an adverse effect
on the fetus, but no adequate studies in humans. Category D reveals evidence of
human fetal risk, but the potential benefits from the use of the drugs in pregnant
women may outweigh potential risks.
Discharge planning for patients leaving the hospital should include instructions
on the use of over-the-counter (OTC) drugs. Which comment by the patient
8. would demonstrate a good understanding of OTC drugs?
A) OTC drugs are safe and do not cause adverse effects if taken properly.
