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NURS 640 Exam 1 | 50 Questions with Answers | Advanced Pathophysiology, Cancer, Respiratory & GI Systems

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This detailed exam preparation resource for NURS 640 – Advanced Pathophysiology contains 50 multiple-choice questions and answers, tailored for the 2025/2026 academic year Exam 1. The document covers advanced topics such as cancer biology (tumor suppressor genes, metastasis, immune evasion), inflammation mechanisms, wound healing, cellular adaptation, acid-base imbalances, and complex disorders affecting the respiratory, gastrointestinal, renal, and hematologic systems. Questions are crafted to assess both fundamental understanding and clinical application of disease mechanisms at a graduate level. Ideal for students in graduate nursing programs, including MSN, DNP, nurse practitioner tracks, and those preparing for advanced clinical practice or pathophysiology certification exams. This document also serves as a strong foundation for case-based learning, classroom quizzes, or self-assessment in advanced health sciences courses. With clearly structured Q&A format and comprehensive coverage of high-yield content, it supports effective, exam-focused review and critical thinking development for advanced practice roles. Keywords: nurs 640, advanced pathophysiology, cancer biology, acid-base balance, inflammation, respiratory disorders, GI system, hematologic system, wound healing, graduate nursing exam, MSN prep, DNP pathophysiology, nurse practitioner review, cellular adaptation, renal disorders

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NURS 640 Exam 1 2025/2026 Exam
Questions and Verified Answers |
Already Graded A+



Chronic care model - 🧠 ANSWER ✔✔focuses on improving care for chronic

diseases. 1. Delivery of high quality care requires a range of strategies that

must closely involve and engage the patient. 2. Team care is essential.


Transitional Care Model (TCM) - 🧠 ANSWER ✔✔APN provides

comprehensive in hospital planning and home follow up care coordination,

including training and support for nurses by a multidisciplinary HF team.

Care plans developed by nurses in collaboration with pt physicians that

reflect pt and caregiver goals and evidence based guidelines; pt and

caregiver education; coordination of care across settings; and nurse

delivered clinical services including medication management.


Care Transitions Intervention (CTI) - 🧠 ANSWER ✔✔A transition coach (RN

or APN) provides tools and teaches self-management and communication

,skills to pt and caregivers so they can coordinate their care and follows up

with home visit and telephone calls. CTI focuses on medication self-

management; pt assembled personal health recorded, primary care and

specialist follow up and teaching the pt how to recognize and follow up on

ref flag symptoms.


Re-Engineered Discharge (project RED) - 🧠 ANSWER ✔✔nurse discharge

advocate provides; pt education, medication reconciliation and education;

instruction about red flags; teach back learning process; coordination of

physician appointments and follow up testing; EBP written discharge plan

shared with pt and all providers. A clinical pharmacist follows up by

telephone to reinforce discharge plan, review medications and solve

problems.


Enhanced Discharge Planning program (EDPP) - 🧠 ANSWER ✔✔master

prepared workers with experience in geriatric and community based

practice provide a phone based intervention to supplement the existing

discharge process; pre discharge review of pt chart and consultation with pt

providers about potential barriers to successful transition; follow up phone

call to assess pt ability to adhere to discharge plan and to determine if

medical and social services specified in the discharge plan have been

,received; to identify medication problems and adherence, ensure

knowledge of red flags. The EDPP model emphasizes addressing

psychosocial and medical issues that emerge after discharge.


Medical decision making - 🧠 ANSWER ✔✔making is a process that you are

continuously evaluating and refining based on new data you obtain. To be

particularly skilled in this, you must be cognizant of the biases you may

bring to your evaluation of the patient's case and the human errors that can

occur during the course of evaluation management. A good clinician looks

at both for their own errors and the errors of colleagues and make the

necessary corrections to avoid harm to the patient.


full compensated - 🧠 ANSWER ✔✔Is pH normal? PaCO2 and HCO3

abnormal


uncompensated. - 🧠 ANSWER ✔✔pH abnormal? PaCO2 or HCO3

abnormal


Mild PAO2 - 🧠 ANSWER ✔✔60-79 mmHg


Moderate PaO2 - 🧠 ANSWER ✔✔40-59mmHg


Severe PaO2 - 🧠 ANSWER ✔✔< 40mmHg



COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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, Metabolic Acidosis - 🧠 ANSWER ✔✔Lactic acidosis, ketoacidosis (diabetic,

alcoholic, starvation), toxins (methanol, salicylates) renal failure (acute or

chronic)


Respiratory alkalosis - 🧠 ANSWER ✔✔§ hypoxia (decreased inspired

oxygen, high altitude, ventilation, hypotension, severe anemia)

§ CNS-mediated disorders (hyperventilation, anxiety, neurologic disease,

CVA, infection, trauma, tumor, drugs, heat, hepatic failure)

§ Pulmonary disease (interstitial lung disease, pneumonia, PE, pulmonary

edema)

§ Mechanical overventilation


Metabolic alkalosis - 🧠 ANSWER ✔✔Excessive body bicarb content (renal

alkalosis, Gastrointestinal alkalosis)


Pulse oximetry - 🧠 ANSWER ✔✔Measures peripheral arterial oxygen

saturation. AKA "the fifth vital sign." In most patients peripheral oxygen

saturation as measured by pulse oximetry (SpO2) provides accurate

information on tissue oxygenation, which allows the clinician to assess and

treat patients who are potentially hypoxemic. As a general principle,

clinicians should pay attention to trends on oxygenation and when treating

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