Neuropharmacology - Advanced Pharm - NURS8024 - Exam Three questions with answers

Neuropharmacology - Advanced Pharm - |\ |\ |\ |\ |\




NURS8024 - Exam Three questions with |\ |\ |\ |\ |\ |\




answers


In Parkinson's disease the amount of __________ lost directly
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correlates to severity of symptoms. - CORRECT ANSWERS|\ |\ |\ |\ |\ |\ |\ |\


✔✔Dopamine


The goal of treatment for Parkinson's disease is to CURE and
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REVERSE degeneration. T / F - CORRECT ANSWERS ✔✔False - Tx
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focus is on restoring balance
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Sinamet (Levodopa & Carbidopa) MOA includes: - CORRECT
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ANSWERS ✔✔Assist in conversion of levodopa to dopamine in the
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basal nigra - Increase in body's production of dopamine
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How does Carbidopa help in Parkinson's disease? - CORRECT
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ANSWERS ✔✔Carbidopa enhances availability of levodopa to
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cross the BBB. Decrease metabolism of levodopa in the GI
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system


An NP understand that treatment effectiveness _____________
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between the 3rd and 5th year of Parkinson treatment using
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sinemet. - CORRECT ANSWERS ✔✔Decreases |\ |\ |\ |\




Important Pt Ed on Levodopa: - CORRECT ANSWERS ✔✔Take on
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an Empty Stomach
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,ADE with Levodopa include: - CORRECT ANSWERS ✔✔CNS effects
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(Visual/Auditory Hallucinations, AIM, depression, GI effects,
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Tachy, Acute glaucoma
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Amantadine is used to treat? - CORRECT ANSWERS ✔✔MINOR
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Parkinsons


MOA for Amantadine includes: - CORRECT ANSWERS ✔✔Enhances
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dopaminergic neurotransmission, muscarininc blocking
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An NP would be cautious in prescribing Amantadine for minor
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Parkinson's in a patient with what dx? - CORRECT ANSWERS
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✔✔Seizure D/O & CHF |\ |\ |\




Name two dopamine receptor agonists: - CORRECT ANSWERS
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✔✔Ropinirole & Pramipexole |\ |\




Name the one anticholingeric for EPS / Parkinsons - CORRECT
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ANSWERS ✔✔Cogentin / Benzotropine |\ |\ |\




ADE of dopamine receptor agonists include: - CORRECT
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ANSWERS ✔✔GI, Postural HYPO, Dyskinesias, confusion,
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delusions, hallucinations, IMPULSIVITY
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Ropinirole and Pramipexole CAUSE: - CORRECT ANSWERS
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✔✔IMPULSIVITY

, Cogentin / Benzotropine is an________________ drug - CORRECT
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ANSWERS ✔✔Anticholinergic |\




MAO-B Inbhitors - CORRECT ANSWERS ✔✔Monamine Oxidase B
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Inhibitors


When prescribing MAO-B Inhibitors use CAUTION with what two
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medications? - CORRECT ANSWERS ✔✔Fluoxetine or Meperidine
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(Prozac or Demerol)
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MAO-B Inhibitors include: - CORRECT ANSWERS ✔✔Selegiline
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(Eldepryl) & Rasagiline (Azilect)
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Use MAO-B Inhibitors _____________ and adjunct with __________. -
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CORRECT ANSWERS ✔✔Early ; Levodopa
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COMT (Catehcol-O-Methyltransferase Inhibitors) - CORRECT
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ANSWERS ✔✔Help with uptake of Levodopa which increases
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dopamine in CNS |\ |\




CAUTION when using _______________ & ___________ as both are
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major enzymes that metabolize catecholamines. - CORRECT
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ANSWERS ✔✔MAO-B and COMT |\ |\ |\




Anticholinergics in Parkinson's disease are prescribed |\ |\ |\ |\ |\ |\


because........ - CORRECT ANSWERS ✔✔Decrease Tremors |\ |\ |\ |\ |\