Lilley-s Pharmacology for Canadian Health Care Practice Ch 23, 24.pdf

Lilley's Pharmacology for
Canadian Health Care
Practice Ch 23, 24

, Main categories of pharmacological drugs used to treat hypertension - CORRECT
ANSWERS-Diuretics
Adrenergic drugs
Vasodilators
Angiotensin-converting enzyme (ACE) inhibitors
Angiotensin receptor blockers (ARBs)
Calcium channel blockers
Direct renin inhibitors

All antihypertensive drugs have some vasodilatory action except for - CORRECT
ANSWERS-Diuretics

Blood pressure is determined by - CORRECT ANSWERS-the product of cardiac output
and systemic vascular resistance

cardiac output - CORRECT ANSWERS-the amount of blood that is ejected from the left
ventricle

systemic vascular resistance - CORRECT ANSWERS-resistance to blood flow
determined by the diameter of the blood vessel and the vascular musculature

All antihypertensives in some way affect - CORRECT ANSWERS-cardiac output

Adrenergic antihypertensive drug category comprises five subcategories - CORRECT
ANSWERS--Adrenergic neuron blockers (central and peripheral)
-α2-receptor agonists (central)
-α1-receptor blockers (peripheral)
-β-receptor blockers (peripheral)
-Combination α1- and β-receptor blockers (peripheral).

Centrally acting adrenergic drugs work by stimulating - CORRECT ANSWERS--Alpha2-
adrenergic receptors in the brain
-Resulting in a lack of norepinephrine production, which reduces blood pressure

alpha 2-adrenergic receptors also affects the kidneys by reducing - CORRECT
ANSWERS-the activity of renin

In the periphery, the α1-blockers results in - CORRECT ANSWERS--Dilating of arteries
and veins
-Urinary output will increase

B-Blockers antihypertensive effects - CORRECT ANSWERS--Reduction in secretion of
renin
-Reduces peripheral vascular resistance