Toxicology Exam Questions and
answers graded 100%
What are the three major types of toxicology? - ANS✅✅Descriptive, Mechanistic, Regulatory
A patient is admitted to the Emergency Room complaining of nausea, vomiting, diarrhea and
anorexia. Which organ system is most likely involved? - ANS✅✅Digestive
Who is Paracelsus? - ANS✅✅All about the dose-father of modern toxicology
Routes, Ordered from most to least toxic - ANS✅✅IV, Inhalation, Oral, Dermal
What is not a type of potential toxic interaction between two chemicals? - ANS✅✅Passive
Which of the following is an assumption of all dose-response relationships? - ANS✅✅There is a
receptor site (or sites) with which the chemical interacts.
Approximately how many mg of an experimental drug would be required for a 70 kg human to give
an equivalent dose of 2 mg in a 20 g mouse? - ANS✅✅7000 mg
A "threshold" dose... - ANS✅✅Is the dose below which the probability of an individual responding
is approximately 0%
What does the "E" in ED50 stand for? - ANS✅✅Effective
What is the major factor that determines the slope of a dose response curve? - ANS✅✅-
Chemicals cause toxicity by reacting with specific target molecules. What are typical attributes of
these target molecules? - ANS✅✅Reactive, accessible, important to the cell
What is the correct order of steps that best describe the mechanisms of how chemicals can cause
toxicity? - ANS✅✅Delivery=>reaction with the target=>toxicity=>repair
answers graded 100%
What are the three major types of toxicology? - ANS✅✅Descriptive, Mechanistic, Regulatory
A patient is admitted to the Emergency Room complaining of nausea, vomiting, diarrhea and
anorexia. Which organ system is most likely involved? - ANS✅✅Digestive
Who is Paracelsus? - ANS✅✅All about the dose-father of modern toxicology
Routes, Ordered from most to least toxic - ANS✅✅IV, Inhalation, Oral, Dermal
What is not a type of potential toxic interaction between two chemicals? - ANS✅✅Passive
Which of the following is an assumption of all dose-response relationships? - ANS✅✅There is a
receptor site (or sites) with which the chemical interacts.
Approximately how many mg of an experimental drug would be required for a 70 kg human to give
an equivalent dose of 2 mg in a 20 g mouse? - ANS✅✅7000 mg
A "threshold" dose... - ANS✅✅Is the dose below which the probability of an individual responding
is approximately 0%
What does the "E" in ED50 stand for? - ANS✅✅Effective
What is the major factor that determines the slope of a dose response curve? - ANS✅✅-
Chemicals cause toxicity by reacting with specific target molecules. What are typical attributes of
these target molecules? - ANS✅✅Reactive, accessible, important to the cell
What is the correct order of steps that best describe the mechanisms of how chemicals can cause
toxicity? - ANS✅✅Delivery=>reaction with the target=>toxicity=>repair
