DASH diet
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, Dietary Approaches to Stop Hypertension
calorie controlled
high grains/fiber, veggies, fruits, nuts
moderate dairy and unsaturated fats
low Na, meat, poultry, fish, alcohol, sweets
-2-4 g Na, 1 oz alcohol for men, 1/2 oz for women
calcium channel blockers
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dihydropyridines -DIPINE (nifedipine, amplodipine)
non-dihydropyridine (diltiazem, verapamil)
prevent Ca ions from entering heart cells causing decreased contractile
force, rate, vasodilation
side effects: reflex tachycardia, dizziness, facial flushing, headache,
peripheral edema
aldosterone antagonists
Give this one a try later!
Spironolactone, Eplerenone
promotes renal excretion of Na and H2O (similar to L sparing diuretics)
causes HYPERKALEMIA, do not use with K supplements or other K sparing
diuretics
useful in hypertension with HF or post MI
hypertension demographics
, Give this one a try later!
more prevalent in southeastern states bc of diet
nearly half of all Americans have high blood pressure
50 and older are at higher risk
ACE inhibitors
Give this one a try later!
-PRIL (captopril, enalapril, lisinopril, quinapril, ramipril)
prevent formation of angiotensin II causing vasodilation, decreased
aldosterone secretion
used alone or with thiazide diuretics
side effects: 1st dose hypotension, cough, hyperkalemia
BEWARE: angioedema (bradykinin mediated), pregnancy (fetal renal
damage)
K-sparing diuretics
Give this one a try later!
spironolactone
aldosterone antagonist in distal nephron, cause Na loss, K retention
least effective of diuretics, often use with other diuretics to offset K loss
DO NOT use with ACE inhibitors, angiotensin II receptor blockers bc
HYPERKALEMIA
caution with salt substitutes- K-based
clinical manifestations
Give this one a try later!
, Dietary Approaches to Stop Hypertension
calorie controlled
high grains/fiber, veggies, fruits, nuts
moderate dairy and unsaturated fats
low Na, meat, poultry, fish, alcohol, sweets
-2-4 g Na, 1 oz alcohol for men, 1/2 oz for women
calcium channel blockers
Give this one a try later!
dihydropyridines -DIPINE (nifedipine, amplodipine)
non-dihydropyridine (diltiazem, verapamil)
prevent Ca ions from entering heart cells causing decreased contractile
force, rate, vasodilation
side effects: reflex tachycardia, dizziness, facial flushing, headache,
peripheral edema
aldosterone antagonists
Give this one a try later!
Spironolactone, Eplerenone
promotes renal excretion of Na and H2O (similar to L sparing diuretics)
causes HYPERKALEMIA, do not use with K supplements or other K sparing
diuretics
useful in hypertension with HF or post MI
hypertension demographics
, Give this one a try later!
more prevalent in southeastern states bc of diet
nearly half of all Americans have high blood pressure
50 and older are at higher risk
ACE inhibitors
Give this one a try later!
-PRIL (captopril, enalapril, lisinopril, quinapril, ramipril)
prevent formation of angiotensin II causing vasodilation, decreased
aldosterone secretion
used alone or with thiazide diuretics
side effects: 1st dose hypotension, cough, hyperkalemia
BEWARE: angioedema (bradykinin mediated), pregnancy (fetal renal
damage)
K-sparing diuretics
Give this one a try later!
spironolactone
aldosterone antagonist in distal nephron, cause Na loss, K retention
least effective of diuretics, often use with other diuretics to offset K loss
DO NOT use with ACE inhibitors, angiotensin II receptor blockers bc
HYPERKALEMIA
caution with salt substitutes- K-based
clinical manifestations