CHEM 334 Lab Final – Verified Questions &
Answers | Certification Ready.
What is the first step in the general mechanism for electrophilic aromatic
substitution? - Correct Answer>>>: addition of the electrophile to the
aromatic ring
What are the two effects that have to be considered to determine the influence
a substituent will have on electrophilic aromatic substitution? - Correct
Answer>>>: inductive and resonance
Why is the nitro group a meta director? - Correct Answer>>>: because
it removes more electron density from the ortho and para positions than the
met position, thus deactivating the meta position less
What is the electrophile in aromatic nitration? - Correct Answer>>>:
NO2+
What is the driving force for losing a proton as the last step in electrophilic
aromatic substitution? - Correct Answer>>>: to reform an aromatic
system
Why is sulfuric acid used in aromatic substitution? - Correct Answer>>>:
to form the active electrophile NO2+
Of the compounds listed, which would be the most reactive toward alkylation? -
Correct Answer>>>: aromatic ring with NH2
Rank the following compounds in order of increasing reactivity toward
electrophilic aromatic substitution. - Correct Answer>>>: B>A>C
Page 1 of 10
, CHEM 334 Lab Final – Verified Questions &
Answers | Certification Ready.
What is the electrophile in the Friedel Crafts alkylation reaction with tert-butyl
alcohol? - Correct Answer>>>: tert butyl cation
Arrange the following compounds in order of decreasing reactivity in
electrophilic substitution. - Correct Answer>>>: II>V>III>I>IV
Which of the following statements is (are) true about electrophilic aromatic
substitution? - Correct Answer>>>: the methoxy group, -OCH3, is an o-
p activator because of a strong electron donating effect
What is a major problem with Friedel-Crafts alkylation? - Correct Answer>>>:
you frequently get over-alkylation
Indicate which of the following acids could be used in the Friedel Crafts
alkylation? - Correct Answer>>>: all of the above
Which of the following reactions would yield isopropyl benzene as the major
product? - Correct Answer>>>: benzene + (CH3)2CH2Cl and AlCl3
Indicate the correct steps that will initiate the Grignard reaction. - Correct
Answer>>>: all of the above
Why do we use anhydrous diethyl ether? - Correct Answer>>>: all of
the above
Page 2 of 10
Answers | Certification Ready.
What is the first step in the general mechanism for electrophilic aromatic
substitution? - Correct Answer>>>: addition of the electrophile to the
aromatic ring
What are the two effects that have to be considered to determine the influence
a substituent will have on electrophilic aromatic substitution? - Correct
Answer>>>: inductive and resonance
Why is the nitro group a meta director? - Correct Answer>>>: because
it removes more electron density from the ortho and para positions than the
met position, thus deactivating the meta position less
What is the electrophile in aromatic nitration? - Correct Answer>>>:
NO2+
What is the driving force for losing a proton as the last step in electrophilic
aromatic substitution? - Correct Answer>>>: to reform an aromatic
system
Why is sulfuric acid used in aromatic substitution? - Correct Answer>>>:
to form the active electrophile NO2+
Of the compounds listed, which would be the most reactive toward alkylation? -
Correct Answer>>>: aromatic ring with NH2
Rank the following compounds in order of increasing reactivity toward
electrophilic aromatic substitution. - Correct Answer>>>: B>A>C
Page 1 of 10
, CHEM 334 Lab Final – Verified Questions &
Answers | Certification Ready.
What is the electrophile in the Friedel Crafts alkylation reaction with tert-butyl
alcohol? - Correct Answer>>>: tert butyl cation
Arrange the following compounds in order of decreasing reactivity in
electrophilic substitution. - Correct Answer>>>: II>V>III>I>IV
Which of the following statements is (are) true about electrophilic aromatic
substitution? - Correct Answer>>>: the methoxy group, -OCH3, is an o-
p activator because of a strong electron donating effect
What is a major problem with Friedel-Crafts alkylation? - Correct Answer>>>:
you frequently get over-alkylation
Indicate which of the following acids could be used in the Friedel Crafts
alkylation? - Correct Answer>>>: all of the above
Which of the following reactions would yield isopropyl benzene as the major
product? - Correct Answer>>>: benzene + (CH3)2CH2Cl and AlCl3
Indicate the correct steps that will initiate the Grignard reaction. - Correct
Answer>>>: all of the above
Why do we use anhydrous diethyl ether? - Correct Answer>>>: all of
the above
Page 2 of 10
