PATHOPHYSIOLOGY EXAM 1QUESTIONS WITH CORRECT ANSWERS 2025

PATHOPHYSIOLOGY EXAM
1QUESTIONS WITH CORRECT
ANSWERS 2025-2026
AnAorderedAphotographicAdisplayAofAaAsetAofAchromosomesAfromAaAsingleAcellAisAa(n):

A)AmetaphaseAspread.

B)Aautosomal Aspread.

C)Akaryotype.

D)AanaphaseAspread.A-AAcorrectAanswersAc

AnAerror AinAwhichAhomologousAchromosomesAfailAtoAseparateAduring AmeiosisAisAtermed:

A)Aaneuploidy.

B)Anondisjunction.

C)Apolyploidy.

D)Aanaplasia.A-AcorrectAanswersAb

AAsomaticAcellAthatAdoesAnotAcontainAaAmultipleAofA23AchromosomesAisAcalled:

A)AanAaneuploidAcell.

B)AaAeuploidAcell.

C)AaApolyploidyAcell.

D)AaAhaploidAcell.A-AcorrectAanswersAa

AA20-year-
oldApregnantAfemaleAgivesAbirthAtoAaAstillbornAchild.AAutopsyArevealsAthatAtheAfetusAhasA92Achr
omosomes.AWhichAofAtheAfollowing AdescribesAthisAcondition?

A)AEuploidy

B)ATriploidy

C)ATetraploidy

D)AAneuploidyA-AcorrectAanswersAc

IfAaApersonAisAaAchromosomal Amosaic,AtheApersonAmay:

A)AbeAaAcarrier AofAtheAgeneticAdisease.

B)AhaveAaAmildAformAofAtheAgeneticAdisease.

,C)AhaveAtwoAgeneticAdiseases.

D)AbeAsterileAasAaAresultAofAtheAgeneticAdisease.A-AcorrectAanswersAb

TheAmostAcommonAcauseAofADownAsyndromeAis:

A)ApaternalAnondisjunction.

B)Amaternal Atranslocations.

C)Amaternal Anondisjunction.

D)ApaternalAtranslocations.A-AcorrectAanswersAc

RiskAfactorsAforADownAsyndromeAinclude:

A)AfetalAexposureAtoAmutagensAinAtheAuterus.

B)AincreasedApaternalAage.

C)AfamilyAhistoryAofADownAsyndrome.

D)ApregnancyAinAwomenAover AageA35.A-AcorrectAanswersAd

AA13-year-
oldAgirlAhasAaAkaryotypeAthatArevealsAanAabsentAhomologousAXAchromosomeAwithAonlyAaAsingl
eAXAchromosomeApresent.AHerAconditionAisAcalled:

A)ADownAsyndrome.

B)ACriAduAchatAsyndrome.

C)ATurner Asyndrome.

D)AEdwardAsyndromeA-AcorrectAanswersAc

AAchildAisAdiagnosedAwithAcysticAfibrosis.AHistoryArevealsAthatAtheAchild'sAparentsAareAfirstAcousi
ns.ACysticAfibrosisAwasAmostAlikelyAtheAresultAof:

A)AXAinactivation.

B)AgenomicAimprinting.

C)Aconsanguinity.

D)AobligateAcarriers.A-AcorrectAanswersAc

Joey,AageA9,AisAadmittedAtoAaApediatricAunitAwithADuchenneAmuscular Adystrophy.AHeAinheritedA
thisAconditionAthroughAa:

A)Asex-linkedAdominantAtrait.

B)Asex-influencedAtrait.

,C)Asex-limitedAtrait.

D)Asex-linkedArecessiveAtrait.A-AcorrectAanswersAd

AA50-year-
oldAmaleAwasArecentlyAdiagnosedAwithAHuntingtonAdisease.ATransmissionAofAthisAdiseaseAisAass
ociatedAwith:

A)Apenetrance.

B)ArecurrenceArisk.

C)Aexpressivity.

D)AdelayedAageAofAonset.A-AcorrectAanswersAd

PeopleAwhoAhaveAneurofibromatosisAwillAshowAvarying AdegreesAofAtheA disease;AthisAisAbecaus
eAofAtheAgeneticAprincipleAof:

A)Apenetrance.

B)Aexpressivity.

C)Adominance.

D)Arecessiveness.A-AcorrectAanswersAb

CysticAfibrosisAisAcausedAbyAanA_____Agene.

A)AX-linkedAdominant

B)AX-linkedArecessive

C)Aautosomal Adominant

D)Aautosomal ArecessiveA-AcorrectAanswersAd

ToAexpressAaApolygenicAtrait:

A)AgenesAmustAinteractAwithAtheAenvironment.

B)AseveralAgenesAmustAactAtogether.

C)AmultipleAmutationsAmustAoccur AinAtheAsameAfamily.

D)AinAsituAcloning AmustAoccur.A-AcorrectAanswersAb

TheAgradualAincreaseAinAheightAamong AtheAhumanApopulationAover AtheApastA100AyearsAisAanAe
xampleAof:

A)ApolygenicAtrait.

B)Amultifactorial Atrait.

, C)Acrossing Aover.

D)Arecombination.A-AcorrectAanswersAb

AAcoupleAhasAthreeAoffspring:AoneAchildAwithAanAautosomalAdominantAdiseaseAtraitAandA twoA w
hoAareAnormal.ATheAfather AisAaffectedAbyAtheAautosomalAdominantAdisease,AbutAtheAmother Ad
oesAnotAhaveAtheAdiseaseAgene.AWhatAisAtheArecurrenceAriskAofAthisAautosomal AdominantAdise
aseAforAtheir AnextAchild?

A)A50%

B)A33%

C)A25%

D)AImpossibleAtoAdetermineA-AcorrectAanswersAa

AA12-year-
oldAmaleAisAdiagnosedAwithAKlinefelter Asyndrome.AHisAkaryotypeAwouldArevealAwhichAofAtheAfo
llowing?

A)AXY

B)AXX

C)AXYY

D)AXXYA-AcorrectAanswersAd

AA5-year-
oldAmaleApresentsAwithAmentalAretardationAandAisAdiagnosedAwithAFragileAXAsyndrome.AWhichA
ofAtheAfollowing AisAmostAlikelyAtoAcauseAthisAsyndrome?

A)ATranslocation

B)AInversion

C)ANondisjunction

D)ADuplicationAatAfragileAsitesA-AcorrectAanswersAd

TheAoutwardAmanifestationAofAaAdisease,AoftenAinfluencedAbyAbothAgenesAandAtheAenvironme
nt,AisAcalledAtheAdisease:

A)Agenotype.

B)Aallele.

C)Aphenotype.

D)Adominance.A-AcorrectAanswersAc