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PATHOLOGY ASSISTANT ASCP EXAM LATEST 2025/2026 QUESTIONS AND VERIFIED ANSWERS

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This detailed exam resource provides the latest 2025/2026 ASCP Pathology Assistant exam questions with verified answers. It covers a wide range of pathology topics including hematology, oncology, cardiopulmonary diseases, renal pathology, endocrine disorders, reproductive system pathology, and congenital anomalies. Each section provides concise explanations of key diseases, histologic features, genetic associations, and clinical correlations. Ideal for students and professionals preparing for the ASCP Pathology Assistant certification, this document serves as a complete and structured review of essential diagnostic pathology concepts.

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PATHOLOGY ASSISTANT ASCP EXAM
LATEST 2025/2026 QUESTIONS AND
VERIFIED ANSWERS




Erythema Muliforme
- correct answer "target" archer's bull's eye lesion



Osler-Weber-Rendu Syndrome
- correct answer Port wine stain, mucus membranes with hemorrhage



Angiosarcoma (hemangiosarcoma)
- correct answer Liver cancer with malignant vascular tumor from exposure to polyvinyl, arsenic and
others



Kaposi Sarcoma
- correct answer AIDS, red-purple macules lower extremities



Pellagra
- correct answer B3 deficiency



Megaloblastic Anemia
- correct answer B12 (Neurologic dysfunction)

Folic Acid (no neuro symptoms)



Vitamin A Deficiency
- correct answer Night blindness and squamous metaplasia



Beriberi
- correct answer B1 deficiency

,Dry: Peripheral Neuropathy

Wet: increased output, cardiac failure



Marasmus
- correct answer Deficient in all nutrients



Kwashiorkor
- correct answer Protein deficient



Right Coronary Artery
- correct answer Posterior RV free wall and septum

Posterior LV



Left Circumflex (from left coronary: right dominant)
- correct answer LV lateral wall



Left Anterior Descending
- correct answer Apex

Anterior LV

Anterior 2/3 Ventricular septum



Arteriolosclerosis
- correct answer Hyaline thickening in vessels (kidneys, hypertension, diabetes)



Atherosclerosis
- correct answer Plaques (atheroma) in vessels



Arteriosclerosis
- correct answer rigidity, thickening of vessels

, Monckeberg Arteriosclerosis
- correct answer Radial and ulnar arteries, calcific sclerosis of the media of arteries (so blood flow is not
obstructed)



Subacute Bacterial Endocarditis
- correct answer Streptococcus Viridans, mitral valve ( also include aortic valve)

IV Drug users= Strep viridans and tricuspid valve

Large, soft, friable easily detached vegetations

Complications: ulceration of valves, perforation of cusps, rupture of chordae tendineae



Nonbacterial Endocarditis (Marantic endocarditis)
- correct answer Metastatic cancer, wasting conditions

Small, sterile fibrin deposits randomly arranged along the line of the valve leaflets

Peripheral embolization

Sterile emboli



Libman-Sacks Endocarditis
- correct answer Lupus

Small vegetations on either or both surfaces of valve leaflets



Endocarditis Carcinoid Syndrome
- correct answer Right side cusps thickened endocardial plaques



Rubella (German Measles)
- correct answer Risk highest shortly before conception to 16th wk gestation



Right Sided Heart Failure
- correct answer Left sided heart failure

Pulmonary hypertension

Right valvular disease (tricuspid and pulmonary)

Left-sided lesions (mitral stenosis)

Congestive hepatosplenomegaly and renal hypoxia

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