100% CORRECT
Thiazide diuretics and loops diuretics have different primary indications because of
which important difference between them? - ANSWER Thiazide diuretics require
luminal perfusion to reach their active state
Which of the following statements about beta-adrenergic blockers is correct? -
ANSWER Some beta-adrenergic blockers are cardioselective, blocking only beta1
receptors; others are not and also block beta2 receptors in smooth muscle.
During diuretic therapy, levels of which electrolyte should be monitored? -
ANSWER Potassium
The beta-adrenergic antagonist nebivolol: - ANSWER Is highly cardioselective.
Which of the following agents is beta1 selective? - ANSWER Atenolol
During diuretic therapy, which of the following should be monitored? -
ANSWER Renal function
Which type of diuretic is available only for oral use? - ANSWER Potassium-
sparing diuretics
Which of the following best characterizes the mechanism of action of diuretics? -
ANSWER Diuretics inhibit the transport of ions across the tubular membrane.
Which of the following is a mechanism of action of beta-adrenergic blockers? -
ANSWER Preventing sympathetic stimulation of the heart
,Which of the following statements about angiotensin II receptor blockers is correct? -
ANSWER Renal alterations are less common than with ACE inhibitors.
When prescribing angiotensin-converting enzyme (ACE) inhibitors, the advanced
practice nurse may anticipate all of the following except: - ANSWER Hypokalemia
The HCN channel blocker ivabradine (Corlanor®) is contraindicated for CHF patients
with: - ANSWER Atrial fibrillation.
The only absolute contraindication to ACE inhibitor use is: - ANSWER Bilateral
renal artery stenosis.
The baseline laboratory evaluation of patients taking ACE inhibitors should include: -
ANSWER Urine protein.
Angiotensin II stimulates the release of which hormone that causes sodium and water
retention in the kidneys? - ANSWER Aldosterone
When considering the use of valsartan/sacubitril (Entresto®) for congestive heart
failure, the NP considers all of the following except: - ANSWER There are few
significant drug-drug interactions.
The renin inhibitor, aliskiren, can significantly reduce the activity of: -
ANSWER Loop diuretics.
Which of the following agents attenuates the hypotensive effects of ACE inhibitors? -
ANSWER Nonsteroidal antiinflammatory agents (NSAIDS)
The most common adverse effects of calcium channel blockers are: -
ANSWER Related to vasodilation.
, Which of the following drug classes is not recommended for the initial treatment of
hypertension in the general non-Black population? - ANSWER Beta-adrenergic
blockers
Which of the following is recommended as prophylaxis in patients at high risk of a
first myocardial infarction episode? - ANSWER Low-dose aspirin
Which of the following agents should be considered in the initial treatment of
hypertension in the general Black population, including those with diabetes? -
ANSWER Calcium-channel blockers
A potential adverse effect associated with the use of phosphodiesterase inhibitors is: -
ANSWER Hypotension.
Which of the following is a mechanism of action of calcium channel blockers? -
ANSWER Decreasing cardiac contractility by inhibiting calcium movement into the
sarcomere (contractile unit of muscle)
Which of the following conditions is a contraindication to thiazide diuretics? -
ANSWER Gout
A patient with significant chronic CHF remains symptomatic despite therapy with ACE
inhibitors and beta-adrenergic antagonists. Before adding digoxin, the advanced
practice nurse should remember that: - ANSWER Laxatives may potentiate
hypokalemia
Which of the following agents should be used as an initial or add-on treatment to
improve kidney outcomes in patients in the general adult population who have
chronic kidney disease and hypertension regardless of race or diabetes status? -
ANSWER ACE inhibitors
Thiazide diuretics and loops diuretics have different primary indications because of
which important difference between them? - ANSWER Thiazide diuretics require
luminal perfusion to reach their active state
Which of the following statements about beta-adrenergic blockers is correct? -
ANSWER Some beta-adrenergic blockers are cardioselective, blocking only beta1
receptors; others are not and also block beta2 receptors in smooth muscle.
During diuretic therapy, levels of which electrolyte should be monitored? -
ANSWER Potassium
The beta-adrenergic antagonist nebivolol: - ANSWER Is highly cardioselective.
Which of the following agents is beta1 selective? - ANSWER Atenolol
During diuretic therapy, which of the following should be monitored? -
ANSWER Renal function
Which type of diuretic is available only for oral use? - ANSWER Potassium-
sparing diuretics
Which of the following best characterizes the mechanism of action of diuretics? -
ANSWER Diuretics inhibit the transport of ions across the tubular membrane.
Which of the following is a mechanism of action of beta-adrenergic blockers? -
ANSWER Preventing sympathetic stimulation of the heart
,Which of the following statements about angiotensin II receptor blockers is correct? -
ANSWER Renal alterations are less common than with ACE inhibitors.
When prescribing angiotensin-converting enzyme (ACE) inhibitors, the advanced
practice nurse may anticipate all of the following except: - ANSWER Hypokalemia
The HCN channel blocker ivabradine (Corlanor®) is contraindicated for CHF patients
with: - ANSWER Atrial fibrillation.
The only absolute contraindication to ACE inhibitor use is: - ANSWER Bilateral
renal artery stenosis.
The baseline laboratory evaluation of patients taking ACE inhibitors should include: -
ANSWER Urine protein.
Angiotensin II stimulates the release of which hormone that causes sodium and water
retention in the kidneys? - ANSWER Aldosterone
When considering the use of valsartan/sacubitril (Entresto®) for congestive heart
failure, the NP considers all of the following except: - ANSWER There are few
significant drug-drug interactions.
The renin inhibitor, aliskiren, can significantly reduce the activity of: -
ANSWER Loop diuretics.
Which of the following agents attenuates the hypotensive effects of ACE inhibitors? -
ANSWER Nonsteroidal antiinflammatory agents (NSAIDS)
The most common adverse effects of calcium channel blockers are: -
ANSWER Related to vasodilation.
, Which of the following drug classes is not recommended for the initial treatment of
hypertension in the general non-Black population? - ANSWER Beta-adrenergic
blockers
Which of the following is recommended as prophylaxis in patients at high risk of a
first myocardial infarction episode? - ANSWER Low-dose aspirin
Which of the following agents should be considered in the initial treatment of
hypertension in the general Black population, including those with diabetes? -
ANSWER Calcium-channel blockers
A potential adverse effect associated with the use of phosphodiesterase inhibitors is: -
ANSWER Hypotension.
Which of the following is a mechanism of action of calcium channel blockers? -
ANSWER Decreasing cardiac contractility by inhibiting calcium movement into the
sarcomere (contractile unit of muscle)
Which of the following conditions is a contraindication to thiazide diuretics? -
ANSWER Gout
A patient with significant chronic CHF remains symptomatic despite therapy with ACE
inhibitors and beta-adrenergic antagonists. Before adding digoxin, the advanced
practice nurse should remember that: - ANSWER Laxatives may potentiate
hypokalemia
Which of the following agents should be used as an initial or add-on treatment to
improve kidney outcomes in patients in the general adult population who have
chronic kidney disease and hypertension regardless of race or diabetes status? -
ANSWER ACE inhibitors
