FPGEE EXAMS SCRIPT 2025/2026 QUESTIONS AND
SOLUTION RATED A+
✔✔Darifenacin (Enablex) - ✔✔cholinergic antagonist
anti-M3
lower frequency of bladder contraction
✔✔★Solifenacin (Vesicare) - ✔✔anti-M3
lower frequency of bladder contraction
✔✔cisatracurium - ✔✔neuromuscular blocker
inhibiting muscular contraction
✔✔Mivacurium (Mivacron) - ✔✔neuromuscular blocker
inhibiting muscular contraction
✔✔Rocuronium (Zemuron) - ✔✔neuromuscular blocker
inhibiting muscular contraction
✔✔Vecuronium (Norcuron) - ✔✔neuromuscular blocker
inhibiting muscular contraction
✔✔★Mirabegron (Myrbetriq) - ✔✔b3
overactive bladder
↑BP
↑digoxin
x CYP2D6 (↑metoprolol)
✔✔cocaine - ✔✔blocks Na/Cl channel
x monoamines(NE, serotonin, dopamine) reuptake
✔✔★Amphetamine (Adderall) - ✔✔↑ release NE, dopamine
x MAO
●ADHA/ narcolepsy/ obesity
↑ alertness
↓ fatigue, appetite
→insomnia
✔✔Phentolamine (Regitine) - ✔✔anti-a1/a2
●diagnosis pheochromocytoma
●hypertension by withdrawal of clonidine
●HT emergency
✔✔★Prazosin (Minipress) - ✔✔anti-a1
↓hypertension
,✔✔★Terazosin (Hytrin) - ✔✔anti-a1
↓hypertension
✔✔★Doxazosin (Cardura) - ✔✔anti-a1
↓hypertension
✔✔Silodosin (Rapaflo) - ✔✔anti-a1A
(α1A-prostate, α1B-vasculature) →relaxing the prostate/ bladder but not ↑BP
↓BPH
✔✔yohimbine - ✔✔anti-a2
erectile dysfunction
✔✔★Timolol (Timoptic) - ✔✔anti-b1,b2
↓aqueous humor of eye
●open-angle glaucoma
x asthma
✔✔Nadolol (Corgard) - ✔✔anti-b1,b2
●HT, angina
●treat HT with concomitant heart diseases/heart failure
x asthma
✔✔Carteolol (Ocupress) - ✔✔anti-b1,b2
↓aqueous humor of eye
●open-angle glaucoma
x asthma
✔✔Levobunolol (Betagan) - ✔✔anti-b1,b2
↓aqueous humor of eye
●open-angle glaucoma
x asthma
✔✔Metipranolol (OptiPranolol) - ✔✔anti-b1,b2
↓aqueous humor of eye
●open-angle glaucoma
●HT
●antiarrhythmic
x asthma
✔✔Betaxolol (Betoptic) - ✔✔anti-b1
HT, glaucoma
●treat HT with concomitant heart diseases/heart failure
,✔✔Acebutolol (Sectral) - ✔✔anti-b1
↓HT
●treat HT with concomitant heart diseases/heart failure
●first-line therapy for chronic stable angina
✔✔★Atenolol (Tenormin) - ✔✔anti-b1
↓BP
●treat HT with concomitant heart diseases/heart failure
●first-line therapy for chronic stable angina
✔✔★Bisoprolol (Zebeta) - ✔✔anti-b1
↓HT
●treat HT with concomitant heart diseases/heart failure
●first-line therapy for chronic stable angina
●chronic heart failure
*extended-release formulation of metoprolol
✔✔Esmolol (Brevibloc) - ✔✔anti-b1
↓HT
●treat HT with concomitant heart diseases/heart failure
●HT emergency
●class II →acute arrhythmias (phase 4) IV only
●first-line therapy for chronic stable angina
✔✔★metoprolol - ✔✔anti-b1
↓HT
●treat HT with concomitant heart diseases/heart failure
●first-line therapy for chronic stable angina
●heart failure (metoprolol succinate XL)
●anti-arrhythmic (phase 4)
✔✔Sacubitril/Valsartan (Entresto) - ✔✔Angiotensin receptor-neprilysin inhibitor (ARNI)
*neprilysin: break down angiotensin I/II, bradykinin, natriuretic peptides
*↑natriuretic peptides→natriuresis/ vasodilation
●heart failure
✔✔★Carvedilol (Coreg) - ✔✔anti-a1, b1, b2
↓HT
●treat HT with concomitant heart diseases/heart failure
●heart failure
●left ventricular dysfunction
✔✔Reserpine (Serpasil) - ✔✔x Mg2+-ATP dependent transport
↓NE
BP
, usually in combination with a thiazide diuretic or vasodilator.
✔✔★levodopa - ✔✔Parkinson's disease
must combine with carbidopa
✔✔★carbidopa - ✔✔x decarboxylase
levodopa→dopamine
✔✔Safinamide (Xadago) - ✔✔parkinson's
x MAO-b
✔✔Entacapone (Comtan) - ✔✔parkinson's
x COMT
levodopa x→3-O-methyldopa
✔✔Tolcapone (Tasmar) - ✔✔parkinson's
x COMT
levodopa x→3-O-methyldopat
✔✔Bromocriptine (Parlodel) - ✔✔D
parkinson's
cause the mental condition to worsen
✔✔Apomorphine (Apokyn) - ✔✔D
parkinson's
acute management of the hypomobility "off" phenomenon in advanced parkinson's
injection
✔✔Rotigotine (Neupro) - ✔✔D
parkinson's
daily patch/injection
✔✔Amantadine (Symmetrel) - ✔✔parkinson's
↑dopamine
x N/M
x NMDA
✔✔★Donepezil (Aricept) - ✔✔x AChE
Alzheimer's
✔✔galantamine - ✔✔x AChE
Alzheimer's
✔✔Rivastigmine (Exelon) - ✔✔x AChE
the only agent approved for the management of (dementia)Alzheimer's with parkinson's
SOLUTION RATED A+
✔✔Darifenacin (Enablex) - ✔✔cholinergic antagonist
anti-M3
lower frequency of bladder contraction
✔✔★Solifenacin (Vesicare) - ✔✔anti-M3
lower frequency of bladder contraction
✔✔cisatracurium - ✔✔neuromuscular blocker
inhibiting muscular contraction
✔✔Mivacurium (Mivacron) - ✔✔neuromuscular blocker
inhibiting muscular contraction
✔✔Rocuronium (Zemuron) - ✔✔neuromuscular blocker
inhibiting muscular contraction
✔✔Vecuronium (Norcuron) - ✔✔neuromuscular blocker
inhibiting muscular contraction
✔✔★Mirabegron (Myrbetriq) - ✔✔b3
overactive bladder
↑BP
↑digoxin
x CYP2D6 (↑metoprolol)
✔✔cocaine - ✔✔blocks Na/Cl channel
x monoamines(NE, serotonin, dopamine) reuptake
✔✔★Amphetamine (Adderall) - ✔✔↑ release NE, dopamine
x MAO
●ADHA/ narcolepsy/ obesity
↑ alertness
↓ fatigue, appetite
→insomnia
✔✔Phentolamine (Regitine) - ✔✔anti-a1/a2
●diagnosis pheochromocytoma
●hypertension by withdrawal of clonidine
●HT emergency
✔✔★Prazosin (Minipress) - ✔✔anti-a1
↓hypertension
,✔✔★Terazosin (Hytrin) - ✔✔anti-a1
↓hypertension
✔✔★Doxazosin (Cardura) - ✔✔anti-a1
↓hypertension
✔✔Silodosin (Rapaflo) - ✔✔anti-a1A
(α1A-prostate, α1B-vasculature) →relaxing the prostate/ bladder but not ↑BP
↓BPH
✔✔yohimbine - ✔✔anti-a2
erectile dysfunction
✔✔★Timolol (Timoptic) - ✔✔anti-b1,b2
↓aqueous humor of eye
●open-angle glaucoma
x asthma
✔✔Nadolol (Corgard) - ✔✔anti-b1,b2
●HT, angina
●treat HT with concomitant heart diseases/heart failure
x asthma
✔✔Carteolol (Ocupress) - ✔✔anti-b1,b2
↓aqueous humor of eye
●open-angle glaucoma
x asthma
✔✔Levobunolol (Betagan) - ✔✔anti-b1,b2
↓aqueous humor of eye
●open-angle glaucoma
x asthma
✔✔Metipranolol (OptiPranolol) - ✔✔anti-b1,b2
↓aqueous humor of eye
●open-angle glaucoma
●HT
●antiarrhythmic
x asthma
✔✔Betaxolol (Betoptic) - ✔✔anti-b1
HT, glaucoma
●treat HT with concomitant heart diseases/heart failure
,✔✔Acebutolol (Sectral) - ✔✔anti-b1
↓HT
●treat HT with concomitant heart diseases/heart failure
●first-line therapy for chronic stable angina
✔✔★Atenolol (Tenormin) - ✔✔anti-b1
↓BP
●treat HT with concomitant heart diseases/heart failure
●first-line therapy for chronic stable angina
✔✔★Bisoprolol (Zebeta) - ✔✔anti-b1
↓HT
●treat HT with concomitant heart diseases/heart failure
●first-line therapy for chronic stable angina
●chronic heart failure
*extended-release formulation of metoprolol
✔✔Esmolol (Brevibloc) - ✔✔anti-b1
↓HT
●treat HT with concomitant heart diseases/heart failure
●HT emergency
●class II →acute arrhythmias (phase 4) IV only
●first-line therapy for chronic stable angina
✔✔★metoprolol - ✔✔anti-b1
↓HT
●treat HT with concomitant heart diseases/heart failure
●first-line therapy for chronic stable angina
●heart failure (metoprolol succinate XL)
●anti-arrhythmic (phase 4)
✔✔Sacubitril/Valsartan (Entresto) - ✔✔Angiotensin receptor-neprilysin inhibitor (ARNI)
*neprilysin: break down angiotensin I/II, bradykinin, natriuretic peptides
*↑natriuretic peptides→natriuresis/ vasodilation
●heart failure
✔✔★Carvedilol (Coreg) - ✔✔anti-a1, b1, b2
↓HT
●treat HT with concomitant heart diseases/heart failure
●heart failure
●left ventricular dysfunction
✔✔Reserpine (Serpasil) - ✔✔x Mg2+-ATP dependent transport
↓NE
BP
, usually in combination with a thiazide diuretic or vasodilator.
✔✔★levodopa - ✔✔Parkinson's disease
must combine with carbidopa
✔✔★carbidopa - ✔✔x decarboxylase
levodopa→dopamine
✔✔Safinamide (Xadago) - ✔✔parkinson's
x MAO-b
✔✔Entacapone (Comtan) - ✔✔parkinson's
x COMT
levodopa x→3-O-methyldopa
✔✔Tolcapone (Tasmar) - ✔✔parkinson's
x COMT
levodopa x→3-O-methyldopat
✔✔Bromocriptine (Parlodel) - ✔✔D
parkinson's
cause the mental condition to worsen
✔✔Apomorphine (Apokyn) - ✔✔D
parkinson's
acute management of the hypomobility "off" phenomenon in advanced parkinson's
injection
✔✔Rotigotine (Neupro) - ✔✔D
parkinson's
daily patch/injection
✔✔Amantadine (Symmetrel) - ✔✔parkinson's
↑dopamine
x N/M
x NMDA
✔✔★Donepezil (Aricept) - ✔✔x AChE
Alzheimer's
✔✔galantamine - ✔✔x AChE
Alzheimer's
✔✔Rivastigmine (Exelon) - ✔✔x AChE
the only agent approved for the management of (dementia)Alzheimer's with parkinson's