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WCU Pathophysiology PATHO 370 Final Exam (2 COMPLETE VERSIONS) 300 Questions and detailed answers Latest Update This Year

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WCU Pathophysiology PATHO 370 Final Exam (2
COMPLETE VERSIONS) 300 Questions and detailed
answers Latest Update This Year
WCU Pathophysiology PATHO 370 Final Exam

QUESTION: Which statement is true regarding cystic fibrosis?

a. It is autosomal-dominant.

b. It affects endocrine glands.

c. It is common in African Americans.

d. It is the most common genetic disease in the United States. - ANSWER-d. It is the most
common genetic disease in the United States.



QUESTION: Which cell is from myeloid lineage? (Select all that apply.)

a. B cells

b. Platelets

c. Monocytes

d. Natural killer cells

e. Granulocytes - ANSWER-b. Platelets

c. Monocytes

e. Granulocytes

, Page 2 of 105


- Platelets, monocytes, and granulocytes are from myeloid lineage

- B cells and natural killer cells are lymphoid



QUESTION: Which statement is true regarding cancer? (Select all that apply.)

a. The greater the undifferentiated cell count, the more aggressive the cancer.

b. Malignant tumors have the potential to kill the host.

c. Benign tumors grow rapidly than malignant ones.

d. Anaplasia means more differentiated cells.

e. Metastasis means less differentiated cells. - ANSWER-a. The greater the undifferentiated cell
count, the more aggressive the cancer.

b. Malignant tumors have the potential to kill the host.




The greater the degree of anaplasia, the more aggressive the malignant tumor.

Malignant tumors, if left untreated, have the potential to kill.

Benign tumors often grow slowly than malignant ones.

Anaplasia is a lack of cell differentiation.

Metastasis means the invasion of cancer to distant sites.



QUESTION: Which is a pathophysiologic change that is consistent with Alzheimer disease?
(Select all that apply)

a. Amyloid plaques

b. Epileptogenic focus

, Page 3 of 105


c. Focal cerebral infarct

d. Neurofibrillary tangles

e. Abnormal serotonin system - ANSWER-a. Amyloid plaques

d. Neurofibrillary tangles




Amyloid plaques and neurofibrillary tangles occur in the brains of Alzheimer patients and are
found at autopsy. Neural thread proteins (tau protein) have a normal function and stabilize
microtubules. In Alzheimer disease, they are chemically altered and twist into paired helical
filaments known as neurofibrillary tangles. Epileptogenic focus is associated with seizure
disorder. Focal cerebral infarct is a stroke occurring in a localized area of the brain.
Abnormalities in the cholinergic system are associated with Alzheimer disease; serotonin
abnormalities are found in depression.




QUESTION: Which statement regarding chronic myeloid leukemia (CML) is a true statement?

a. It is not seen in children.

b. It represents 30% of all cases of leukemia.

c. The average age of onset is older than 70 years.

d. Affected persons carry the Philadelphia chromosome. - ANSWER-d. Affected persons carry
the Philadelphia chromosome.




Philadelphia chromosome occurs in this leukemia. CML occurs occasionally in children and
adolescents. CML represents approximately 15% of all cases of leukemia in the US. The average
age of onset is between 40-50 years.

, Page 4 of 105


Narcotic administration should be administered carefully in patients with acute pancreatitis
related to potential for

a. respiratory depression.

b. narcotic dependency.

c. sphincter of Oddi dysfunction.

d. allergic reaction. - ANSWER-c. sphincter of Oddi dysfunction




QUESTION: A patient is admitted to the hospital with left-sided heart failure. Which clinical
manifestation would the nurse expect the client to exhibit? (Select all that apply.)

a. Cough

b. Dyspnea

c. Bradypnea

d. Crackles in lungs

e. Peripheral edema - ANSWER-a. Cough

b. Dyspnea

d. Crackles in lungs




QUESTION: Which offers the best prognosis for the cure of cancer?

a. Surgery

b. Radiation

c. Early detection

d. Chemotherapeutic agents - ANSWER-c. Early detection

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