USMLE Step 2 CK: Causes of Hypoxemia and Respiratory Acidosis With complete solution– Expert Verified | Latest Version | 100 Guaranteed Success

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USMLE Step 2 CK: Causes of Hypoxemia and Respiratory Acidosis With complete solution– Expert Verified | Latest Version | 100 Guaranteed Success

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2025/2026

Institution USMLE - United States Medical Licensing

Course USMLE - United States Medical Licensing

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USMLE Step 2 CK: Causes of Hypoxemia and Respiratory Acidosis With complete solution– Expert Verified | Latest Version | 100 Guaranteed Success

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USMLE Step 2 CK: Causes of Hypoxemia and Respiratory
Acidosis With complete solution– Expert Verified | Latest
Version | 100 Guaranteed Success

What is the patient's arterial blood gas pH value indicating respiratory acidosis? -
7

What is the primary cause of the patient's hypoxemia? - Alveolar hypoventilation

What are the arterial blood gas values for PaO2 and PaCO2 in this patient? -
PaO2: 62 mm Hg, PaCO2: 59 mm Hg

What is the significance of an elevated PaCO2 in this patient? - It indicates
respiratory acidosis due to hypoventilation.

What are some causes of alveolar hypoventilation? - Chronic obstructive
pulmonary disease, obesity hypoventilation, neuromuscular diseases, drug-
induced hypoventilation, and central nervous system dysfunction.

What is the A-a gradient calculated for this patient? - 14 (A-a gradient = PaO2 -
PaO2 = 78 - 62 = 16)

What does a normal A-a gradient indicate in the context of hypoxemia? - It
suggests that hypoxemia may be due to hypoventilation rather than V/Q
mismatch.

What is the normal range for an A-a gradient? - A normal A-a gradient is <15; >30
is considered elevated.

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Uploaded on: October 9, 2025
Number of pages: 3
Written in: 2025/2026
Type: Exam (elaborations)
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