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Levodopa MOA - 🧠ANSWER ✔✔Reduces symptoms by increasing
dopamine synthesis in the striatum
Levodopa Adverse Effects - 🧠ANSWER ✔✔Nausea and Vomiting
Levodopa Absorption - 🧠ANSWER ✔✔Food delays absorption, no high
protein foods
Carbidopa MOA - 🧠ANSWER ✔✔Carbidopa is used to enhance the effects
of levodopa
Benztropine Uses - 🧠ANSWER ✔✔Reduce tremor and possibly rigidity
Donepezil MOA - 🧠ANSWER ✔✔Cholinesterase inhibitor, prevents
breakdown of acetylcholine
, Donepezil therapeutic benefits of drugs - 🧠ANSWER ✔✔Helps slow
progression of AD
Donepezil dosing - 🧠ANSWER ✔✔PO only
5 mg once daily x 4 - 6 weeks then
Increase to 10 mg daily
Interferon Beta MOA - 🧠ANSWER ✔✔immunomodulators, helps protect
nerve cells
Interferon Beta Uses - 🧠ANSWER ✔✔Reduces the frequency and severity
of parkinson attacks Reduces the number and size of lesions detectable
with magnetic resonance imaging
Delays progression of disability
Interferon Beta side/adverse effects - 🧠ANSWER ✔✔Flu-like reactions
Hepatotoxicity
Myelosuppression
Injection-site reactions
Depression