Correct Answers 2025
Antifungals ,in ,newborns ,(nystatin ,and ,fluconazole) ,- ,CORRECT ,ANSWER-Used ,to
,treat ,candidiasis ,in ,newborns
Safe ,in ,low ,dose ,- ,CORRECT ,ANSWER-Antifungals ,for ,children ,are
Weigh ,risk/benefit ,- ,CORRECT ,ANSWER-antifungals ,in ,pregnancy ,should...
Safe ,in ,low ,dose ,except ,Ketoconazole ,- ,CORRECT ,ANSWER-Antifungals ,while
,breastfeeding
Ketoconazole ,- ,CORRECT ,ANSWER-Antifungal ,that ,should ,not ,be ,given ,while
,breastfeeding ,due ,to ,hepatotoxicity
Systemic ,and ,Superficial ,- ,CORRECT ,ANSWER-two ,categories ,of ,antifungals
Amphotericin ,B ,(Abelcet) ,- ,CORRECT ,ANSWER-Polyene ,Antifungal ,used ,only ,for
,systemic, ,broad ,spectrum
Amphotericin ,B ,(Polyene ,Antifungal) ,- ,CORRECT ,ANSWER-Abelect
Amphotericin ,B ,(Abelcet) ,(Polyene ,Antifungal) ,- ,CORRECT ,ANSWER-Binds ,to
,components ,of ,the ,fungal ,cell ,membrane ,reducing ,viability, ,binds ,to ,sterol ,so
,ergosterol ,must ,be ,present ,for ,drug ,to ,work
Amphotericin ,B ,(Abelcet) ,(Polyene ,Antifungal) ,- ,CORRECT ,ANSWER-Antifungal ,with
,BBW ,only ,used ,in ,infections ,that ,are ,potentially ,fatal ,due ,to ,potential ,harm
Amphotericin ,B ,(Abelcet) ,(Polyene ,Antifungal) ,- ,CORRECT ,ANSWER-•DOC ,for ,most
,systemic ,mycoses
•Aspergillus ,spp
•Brown-black ,molds
•Leishmania ,spp
Hypersensitivity ,and ,renal ,impairment ,- ,CORRECT ,ANSWER-Amphotericin ,B
,(Abelcet) ,contraindications
, Renal ,function, ,CBC ,- ,CORRECT ,ANSWER-two ,labs ,for ,amphotericin ,B ,(Polyene
,Antifungal)
Amphotericin ,B ,(Abelcet) ,(Polyene ,Antifungal) ,- ,CORRECT ,ANSWER-Antifungal ,that
,only ,comes ,in ,an ,IV ,dose
Nystatin ,- ,CORRECT ,ANSWER-In ,the ,same ,family ,as ,Amphotericin ,B ,(Polyene
,Antifungal)
Amphotericin ,B ,(Abelcet) ,(Polyene ,Antifungal) ,- ,CORRECT ,ANSWER-Antifungal ,often
,•Premed ,with ,Benadryl, ,Tylenol, ,and ,hydrocortisone
•Demerol ,for ,Rigors
Due ,to ,adverse ,effects
Amphotericin ,B ,(Abelcet) ,(Polyene ,Antifungal) ,- ,CORRECT ,ANSWER-antifungal ,with
,prolonged ,treatment ,(6-8 ,weeks), ,renal ,dosing ,(decrease ,dose ,for ,creatinine ,over ,3.5
,(impaired ,renal ,fx))
Amphotericin ,B ,(Abelcet) ,(Polyene ,Antifungal) ,- ,CORRECT ,ANSWER-antifungal ,that
,frequently ,causes ,infusion ,reactions ,caused ,by ,release ,of ,proinflammatory ,cytokines
,(tumor ,necrosis ,factor, ,interleukin-1, ,interleukin-6) ,from ,monocytes ,and ,macrophages.
,Symptoms ,begin ,1 ,to ,3 ,hours ,after ,starting ,the ,infusion ,and ,persist ,about ,an ,hour
Amphotericin ,B ,(Abelcet) ,(Polyene ,Antifungal) ,- ,CORRECT ,ANSWER-Patient
,education ,includes ,teaching ,about ,infusion ,reactions ,for ,this ,antifungal
Symptoms ,of ,infusion ,reactions ,- ,CORRECT ,ANSWER-fever, ,chills, ,rigor, ,nausea,
,headache ,are ,symptoms ,of
diphenhydramine ,plus ,acetaminophen ,- ,CORRECT ,ANSWER-Mild ,infusion ,reactions
,related ,to ,Amphotericin ,B ,can ,be ,reduced ,by ,pretreatment ,with
hydrocortisone ,- ,CORRECT ,ANSWER-If ,other ,measures ,fail, ,this ,can ,be ,used ,to
,decrease ,fever ,and ,chills ,related ,to ,amphotericin ,B ,. ,However, ,because ,it ,can ,reduce
,the ,patient's ,ability ,to ,fight ,infection, ,routine ,use ,of ,should ,be ,avoided
lipid-based ,amphotericin ,- ,CORRECT ,ANSWER-Infusion ,reactions ,are ,less ,intense
,with ,this ,amphotericin ,formulation ,than ,with ,the ,conventional ,formulation.
1 ,L ,of ,Saline ,- ,CORRECT ,ANSWER-. ,Kidney ,damage ,can ,be ,minimized ,by ,infusing
,this ,on ,the ,days ,amphotericin ,is ,given.
Amphotericin ,B ,(abelcet) ,Poly ,Antifungal ,- ,CORRECT ,ANSWER-Adverse ,Effects:
•Serious ,AE
•Infusion ,reactions ,à ,fever, ,chills, ,rigors, ,N, ,HA