WGU785 |
Final Exam
|
|Latest2021 |
Q&A
|
,WGU 785 Final Exam Latest 2021 With
| | | | | |
Complete Solution |
Hemophilia |Pedigree |- |Father |has |hemophilia, |mother |does |not. |What |is |the |outcome |for
|their |kids?
Correct |answer- |His |daughters |would |be |carriers. |This |is |x-link |recessive.
Autosomal:
Dominant:
Correct |answer- |Autosomal: |males |and |females |equally |affected. |Dominant:
|non-carrier |parents
polymerase |chain |reaction |(PCR)
Correct |answer- |The |process |of |copying |DNA |in |the |lab. |Uses |Template |DNA,
|Nucleotides |(dNTPS), |DNA |Polymerase, |and |DNA |primers.
3 |Steps |of |PCR
Correct |answer- |1. |Denaturation: |DNA |is |heated |to |95C |to |separate |it.
2. Annealing: |reaction |is |cooled |to |50C; |primers |stick |to |the |DNA |you |want |to |copy |and
|add |DNA |polymerase.
3. Elongation: |reaction |heated |to |70C |and |DNA |polymerase, |adding |nucleotides |building |a
|new |DNA |strand.
Base |Excision |Repair |(BER)
Correct |answer- |How |you |repair |a |mutation. |BER |is |used |to |repair |damage |to |a |base |caused
|by |harmful |molecules. |You |remove |the |base |that |is |damaged |and |replace |it.
*BER |removes |a |single |nucleotide*
DNA |glycolsylase |- |sees |damaged |DNA |and |removes |it.
DNA |polymerase-puts |the |right |one |back |in |while |DNA |ligase |seals |it.
Mismatch |repair |(MMR) |occurs |during:
Correct |answer- |replication. |DNA |polymerase |proofreads |but |sometimes |a |mismatch
|pair |gets |through. |MMR |removes |a |large |section |of |the |nucleotides |from |the |new |DNA
|and |DNA |polymerase |tries |again. |(Ex: |C-T |instead |of |C-A)
Mismatch |Repair |corrects |what |kind |of |DNA |damage?
Correct |answer- |When |a |base |is |mismatched |due |to |errors |in |replication. |Such |as |G-T
|instead |of |G-C. |DNA |polymerase |comes |by |and |fixes |it.
What |happens |when |DNA |polymerase |binds |to |DNA |to |make |RNA?
, Correct |answer- |TRANSCRIPTION! |DNA |polymerase |takes |the |individual |nucleotides
|and |matches |them |to |the |parental |sequences |to |ensure |a |correct |pair. |It |must |bind |with
|RNA |primer |to |work.
What |is |needed |for |DNA |replication?
|Correct |answer- |DNA |polymerase
Nonsense |Mutation
Correct |answer- |Change |in |1 |nucleotide |produces |a |STOP |codon |Stop= |nonsense |because
|it |is |no |more.
Silent |Mutation
Correct |answer- |Change |in |1 |nucleotide |but |codes |for |the |same |amino |acid. |Silent= |the
|change |doesn't |change |the |name |of |the |protein
Missense |Mutation
Correct |answer- |Change |in |1 |nucleotide |leads |to |a |code |for |a |different |amino |acid. |Missense
|= |mistake |was |made.
What |happends |during |RNA |splicing?
Correct |answer- |During |RNA |splicing |introns |are |cut |out, |the |remaining |exons |are |joined
|together.
5'ATG |AGT |CTC |TCT |3'
Find |the |DNA |template |strand.
Correct |answer- |3'TAC |TCA |GAG |AGA |5'
The |DNA |template |strand |is |complimentary. |So |start |with |the |opposite |number, |then |go
|L-R |with |the |complimentary |letter.
5'ATG |AGT |CTC |TCT |3'
What |is |the |corresonding |mRNA |sequence?
|Correct |answer- |5'AUG |AGU |CUC |UCU |3'
This |sequence |is |the |same |as |the |coding |strand |except |T |changes |to |U |because |it |is
|RNA. |RNA |doesn't |have |T.
How |would |a |mutation |from |CTC |to |ATC |affect |the |protein |sequence? |(CTC/ATC |- |coding
|strand, |AUC |- |mRNA |strand)
Correct |answer- |This |will |make |a |missense |mutation |because |it |changes |the |name |of |the
|protein. |(look |at |the |chart |provided.) |missense |= |mistake
DNA |replication |process
Correct |answer- |DNA |->Transcription |-> |RNA |-> |Translation |-> |Polypeptide
Describe |how |you |would |find |what |ionized |Alanine |looks |like.
Final Exam
|
|Latest2021 |
Q&A
|
,WGU 785 Final Exam Latest 2021 With
| | | | | |
Complete Solution |
Hemophilia |Pedigree |- |Father |has |hemophilia, |mother |does |not. |What |is |the |outcome |for
|their |kids?
Correct |answer- |His |daughters |would |be |carriers. |This |is |x-link |recessive.
Autosomal:
Dominant:
Correct |answer- |Autosomal: |males |and |females |equally |affected. |Dominant:
|non-carrier |parents
polymerase |chain |reaction |(PCR)
Correct |answer- |The |process |of |copying |DNA |in |the |lab. |Uses |Template |DNA,
|Nucleotides |(dNTPS), |DNA |Polymerase, |and |DNA |primers.
3 |Steps |of |PCR
Correct |answer- |1. |Denaturation: |DNA |is |heated |to |95C |to |separate |it.
2. Annealing: |reaction |is |cooled |to |50C; |primers |stick |to |the |DNA |you |want |to |copy |and
|add |DNA |polymerase.
3. Elongation: |reaction |heated |to |70C |and |DNA |polymerase, |adding |nucleotides |building |a
|new |DNA |strand.
Base |Excision |Repair |(BER)
Correct |answer- |How |you |repair |a |mutation. |BER |is |used |to |repair |damage |to |a |base |caused
|by |harmful |molecules. |You |remove |the |base |that |is |damaged |and |replace |it.
*BER |removes |a |single |nucleotide*
DNA |glycolsylase |- |sees |damaged |DNA |and |removes |it.
DNA |polymerase-puts |the |right |one |back |in |while |DNA |ligase |seals |it.
Mismatch |repair |(MMR) |occurs |during:
Correct |answer- |replication. |DNA |polymerase |proofreads |but |sometimes |a |mismatch
|pair |gets |through. |MMR |removes |a |large |section |of |the |nucleotides |from |the |new |DNA
|and |DNA |polymerase |tries |again. |(Ex: |C-T |instead |of |C-A)
Mismatch |Repair |corrects |what |kind |of |DNA |damage?
Correct |answer- |When |a |base |is |mismatched |due |to |errors |in |replication. |Such |as |G-T
|instead |of |G-C. |DNA |polymerase |comes |by |and |fixes |it.
What |happens |when |DNA |polymerase |binds |to |DNA |to |make |RNA?
, Correct |answer- |TRANSCRIPTION! |DNA |polymerase |takes |the |individual |nucleotides
|and |matches |them |to |the |parental |sequences |to |ensure |a |correct |pair. |It |must |bind |with
|RNA |primer |to |work.
What |is |needed |for |DNA |replication?
|Correct |answer- |DNA |polymerase
Nonsense |Mutation
Correct |answer- |Change |in |1 |nucleotide |produces |a |STOP |codon |Stop= |nonsense |because
|it |is |no |more.
Silent |Mutation
Correct |answer- |Change |in |1 |nucleotide |but |codes |for |the |same |amino |acid. |Silent= |the
|change |doesn't |change |the |name |of |the |protein
Missense |Mutation
Correct |answer- |Change |in |1 |nucleotide |leads |to |a |code |for |a |different |amino |acid. |Missense
|= |mistake |was |made.
What |happends |during |RNA |splicing?
Correct |answer- |During |RNA |splicing |introns |are |cut |out, |the |remaining |exons |are |joined
|together.
5'ATG |AGT |CTC |TCT |3'
Find |the |DNA |template |strand.
Correct |answer- |3'TAC |TCA |GAG |AGA |5'
The |DNA |template |strand |is |complimentary. |So |start |with |the |opposite |number, |then |go
|L-R |with |the |complimentary |letter.
5'ATG |AGT |CTC |TCT |3'
What |is |the |corresonding |mRNA |sequence?
|Correct |answer- |5'AUG |AGU |CUC |UCU |3'
This |sequence |is |the |same |as |the |coding |strand |except |T |changes |to |U |because |it |is
|RNA. |RNA |doesn't |have |T.
How |would |a |mutation |from |CTC |to |ATC |affect |the |protein |sequence? |(CTC/ATC |- |coding
|strand, |AUC |- |mRNA |strand)
Correct |answer- |This |will |make |a |missense |mutation |because |it |changes |the |name |of |the
|protein. |(look |at |the |chart |provided.) |missense |= |mistake
DNA |replication |process
Correct |answer- |DNA |->Transcription |-> |RNA |-> |Translation |-> |Polypeptide
Describe |how |you |would |find |what |ionized |Alanine |looks |like.
