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Pathophysiology 6501 Advanced midterm exam 2025/2026

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Pathophysiology 6501

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Pathophysiology 6501 Advanced
midterm


➢ A patient with kidney disease presents with urine that has a fixed specific gravity of

1.010, regardless of fluid intake. The nurse practitioner suspects isosthenuria. What best

defines isosthenuria, and why might the loss of papillae lead to this condition?

Isosthenuria is the inability to concentrate or dilute urine properly, and the loss of

papillae reduces the number of collecting ducts availabke for urine.



➢ In the renal system, when there is a reduction in urine flow through the tubules, what is

the initial even that initiated a series of processes aimed at increasing tubular flow by

elevating the glomerular filtration rate (GFR)? Decreased delivery of sodium

chloride to the macula densa




➢ An adult patient experiences abdominal pain in the upper right side, accompanied by

nausea and vomiting, especially after eating fatty foods. Which hormone is mainly

responsible for stimulating the contraction of the bile storage organ and prompting the

release of bile in response to high fat meals? Cholecystokinin



➢ A 45 year old patient presents with frequent heartburn, regurgitation of stomach

contents, and a sour taste in the mouth. Symptoms worsen when lying down and are

relieved by antacids. On examination, there are no alarming features. Which of the

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