1|Page
WGU D116 ADVANCED PHARMACOLOGY OA AND PRE
ASSESSMENT EXAM NEWEST 2025/2026 ACTUAL EXAM WITH
COMPLETE QUESTIONS AND CORRECT DETAILED ANSWERS (100%
VERIFIED ANSWERS) |ALREADY GRADED A+| ||PROFESSOR
VERIFIED||
A patient is admitted to a hospital with symptoms of heart failure
that include dyspnea, fatigue, peripheral edema, and distention of
the jugular veins. Further assessment reveals left ventricular
hypertrophy and evidence of a previous myocardial infarction.
Which medication regimen should an advanced practice
registered nurse recommend for this patient?
Digoxin alone as a first-line drug
Calcium channel blocker and antidysrhythmic agent
Digoxin, NSAIDS, and hydrochlorothiazide
Diuretic, ACE inhibitor, and beta-blocker - ANSWER-Diuretic,
ACE inhibitor, and beta-blocker
An advanced practice registered nurse (APRN) is evaluating a
new patient in a clinic. The patient is currently taking propranolol
40 mg twice daily, captopril 12.5 mg twice daily, albuterol inhaler
,2|Page
two puffs every six hours as needed, salmeterol inhaler two puffs
twice daily, and aspirin 81 mg daily.
The patient has known diagnoses of cardiovascular disease and
asthma. The patient states that the use of albuterol has become
more frequent, often up to six times per day, even though it was
rarely used in the past.
Which action should the APRN take for this patient?
Change the propranolol to metoprolol 50 mg per day
Add fluticasone nasal spray twice daily
Change captopril to lisinopril 20 mg per day
Add albuterol 2.5 mg nebulization every four hours - ANSWER-
Change the propranolol to metoprolol 50 mg per day
An advanced practice registered nurse (APRN) is seeing a patient
who has stage 4 chronic kidney disease in a clinic. The patient
has swelling of bilateral extremities, blood pressure of 140/80,
pulse of 88, respirations of 16, and a temperature of 98.0°F.
The patient is currently taking losartan 50 mg daily, metoprolol
100 mg daily, and metformin 1 g daily. The APRN discusses
adding a diuretic to the patient's regimen.
,3|Page
Which medication should be used for this purpose with this
patient?
Hydrochlorothiazide 25 mg daily
Spironolactone 25 mg daily
Furosemide 20 mg daily
Chlorthalidone 25 mg daily - ANSWER-Furosemide 20 mg daily
A patient presents to an emergency department with a blood
pressure of 180/98 and complaints of chest pain, blurred vision,
and a headache. An advanced practice registered nurse
prescribes an ACE inhibitor (enalapril 40 mg stat).
What is the pharmacological effect of this medication?
Causes dilation of arterioles and veins
Lowers the angiotensin II level and dilates blood vessels
Decreases plasma renin activity by 50%-80%
Blocks receptors for aldosterone - ANSWER-Lowers the
angiotensin II level and dilates blood vessels
, 4|Page
An advanced practice registered nurse (APRN) is treating a 57-
year-old female for hypertension. She is relatively healthy except
for a history of asthma. The APRN plans to start her on an ACE
inhibitor-diuretic combination.
Which side effect indicates a change should be made in this
choice of medication?
Cough
Loose stool
Headache
Frequent urination - ANSWER-Cough
A patient presents to a clinic to follow up on allergic rhinitis. The
patient has been taking cetirizine 10 mg/d with decreased
sneezing and itchiness of nose but reports no improvement in
nasal stuffiness. An advanced practice registered nurse (APRN)
prescribes pseudoephedrine 120 mg bid for four days to treat
nasal congestion.
Which adverse effect is associated with prolonged use of this
medication?
Rebound congestion
WGU D116 ADVANCED PHARMACOLOGY OA AND PRE
ASSESSMENT EXAM NEWEST 2025/2026 ACTUAL EXAM WITH
COMPLETE QUESTIONS AND CORRECT DETAILED ANSWERS (100%
VERIFIED ANSWERS) |ALREADY GRADED A+| ||PROFESSOR
VERIFIED||
A patient is admitted to a hospital with symptoms of heart failure
that include dyspnea, fatigue, peripheral edema, and distention of
the jugular veins. Further assessment reveals left ventricular
hypertrophy and evidence of a previous myocardial infarction.
Which medication regimen should an advanced practice
registered nurse recommend for this patient?
Digoxin alone as a first-line drug
Calcium channel blocker and antidysrhythmic agent
Digoxin, NSAIDS, and hydrochlorothiazide
Diuretic, ACE inhibitor, and beta-blocker - ANSWER-Diuretic,
ACE inhibitor, and beta-blocker
An advanced practice registered nurse (APRN) is evaluating a
new patient in a clinic. The patient is currently taking propranolol
40 mg twice daily, captopril 12.5 mg twice daily, albuterol inhaler
,2|Page
two puffs every six hours as needed, salmeterol inhaler two puffs
twice daily, and aspirin 81 mg daily.
The patient has known diagnoses of cardiovascular disease and
asthma. The patient states that the use of albuterol has become
more frequent, often up to six times per day, even though it was
rarely used in the past.
Which action should the APRN take for this patient?
Change the propranolol to metoprolol 50 mg per day
Add fluticasone nasal spray twice daily
Change captopril to lisinopril 20 mg per day
Add albuterol 2.5 mg nebulization every four hours - ANSWER-
Change the propranolol to metoprolol 50 mg per day
An advanced practice registered nurse (APRN) is seeing a patient
who has stage 4 chronic kidney disease in a clinic. The patient
has swelling of bilateral extremities, blood pressure of 140/80,
pulse of 88, respirations of 16, and a temperature of 98.0°F.
The patient is currently taking losartan 50 mg daily, metoprolol
100 mg daily, and metformin 1 g daily. The APRN discusses
adding a diuretic to the patient's regimen.
,3|Page
Which medication should be used for this purpose with this
patient?
Hydrochlorothiazide 25 mg daily
Spironolactone 25 mg daily
Furosemide 20 mg daily
Chlorthalidone 25 mg daily - ANSWER-Furosemide 20 mg daily
A patient presents to an emergency department with a blood
pressure of 180/98 and complaints of chest pain, blurred vision,
and a headache. An advanced practice registered nurse
prescribes an ACE inhibitor (enalapril 40 mg stat).
What is the pharmacological effect of this medication?
Causes dilation of arterioles and veins
Lowers the angiotensin II level and dilates blood vessels
Decreases plasma renin activity by 50%-80%
Blocks receptors for aldosterone - ANSWER-Lowers the
angiotensin II level and dilates blood vessels
, 4|Page
An advanced practice registered nurse (APRN) is treating a 57-
year-old female for hypertension. She is relatively healthy except
for a history of asthma. The APRN plans to start her on an ACE
inhibitor-diuretic combination.
Which side effect indicates a change should be made in this
choice of medication?
Cough
Loose stool
Headache
Frequent urination - ANSWER-Cough
A patient presents to a clinic to follow up on allergic rhinitis. The
patient has been taking cetirizine 10 mg/d with decreased
sneezing and itchiness of nose but reports no improvement in
nasal stuffiness. An advanced practice registered nurse (APRN)
prescribes pseudoephedrine 120 mg bid for four days to treat
nasal congestion.
Which adverse effect is associated with prolonged use of this
medication?
Rebound congestion
