Nr 507 Advance Patho. Midterm Exam Questions With Correct Verified Answers | 100% Pass (A+ Certified)

NR 507 ADVANCE PATHO. MIDTERM EXAM QUESTIONS WITH CORRECT VERIFIED ANSWERS | 100% PASS (A+ CERTIFIED) 1. Hypersensitivity Correct Answer Type 1: •Type 1: Allergic reaction •Mediated by IgE •Inflammation due to mast cell degranulation •Local symptoms: itching, rash •Systemic symptoms: wheezing •Most dangerous form is an anaphylactic reaction-systemic response-hypotension, severe bronchoconstriction •Main treatment: epinephrine reverses the effects 2. Hypersensitivity Correct Answer Type 2: •Type 2: Cytotoxic reaction; tissue specific (e.g. thyroid tissue) •Macrophages are the primary effectors cells involved •Can cause tissue damage or alter function •Grave's disease (hyperthyroidism)-example of altering thyroid function, but does not destroy thyroid tissue •Incompatible blood type-example of cell/tissue damage that occurs; severe transfusion reaction occurs and the transfused erythrocytes are destroyed by agglutination or complement-mediated lysis. 3. Difference Between Type 2 and Type 3: •Type 3 is not organ specific the antibody binds to soluble antigen outside the cell surface that was released into the blood or body fluids, and the complex is then deposited in the tissues 4. Difference Between Type 2 and Type 3 Correct Answer •Type 2 is organ specific •The antibody binds to the antigen on the cell surface 5. Hypersensitivity Correct Answer Type 3-Examples: •Rheumatoid arthritis-antigen/antibodies are deposited in the joints •Systemic Lupus Erythematosus (SLE)-very closely related to