ATI Pharmacology
Study online at https://quizlet.com/_4cte0s
1. Therapeutic 0.8 to 2.0 ng/ml
Drug Levels: Toxic Level: greater than 3.4 ng/ml
Digoxin
2. CLONIDINE Adverse Effects/Nursing Considerations:
Drowsiness/sedation - will improve with time, careful to avoid driving and other
activities
Dry mouth - will improve with time, suck on hard candy
Constipation - drink lots of water
Rebound hypertension - don't stop suddenly (can be given oral, and transdermal)
- wean off over 1-2 weeks
Administer patch on hairless, clean, dry skin and be sure to remove old patch
Other patient teaching - avoid taking with alcohol and other medications that
cause drowsiness!
3. Therapeutic 0.5 to 0.8 ng/ml A 58 year old who doesn't listen
Drug Levels:
Gentamicin
4. sargramostim increases WBC
5. Therapeutic 1.5 to 5.0 mcg/ml
Drug Levels: Toxic Level: greater than 5 mcg/ml
Lidocaine
6. Therapeutic 0.4 to 1.0 mEq/L
Drug Levels: Toxic Level: greater than 1.5 mEq/L
Lithium
7. Therapeutic 4 to 8 mg/dL
Drug Levels: Toxic Level: greater than 9 mg/dL
Magnesium
Sulfate
, ATI Pharmacology
Study online at https://quizlet.com/_4cte0s
8. Therapeutic 10 to 30 mcg/ml
Drug Levels: Toxic Level: greater than 40 mcg/ml
Phenobarbital
9. GENTAMYCIN 58 year old with bad kidneys, who doesn't listen, and can't see because he fell in
a trough and got a rash.
Nephrotoxicity - monitor and report!
Hearing loss (ototoxicity) - ringing in ear, headache, dizziness, vertigo; stop and
notify the physician
Neurologic (numbness, tingling, weakness, optic nerve dysfunction (visual
changes) - monitor and report
Hypersensitivity - report rash, urticaria
Monitor peak and trough
Peak - 30 minutes AFTER administration
Trough - right BEFORE next dose
10. salmeterol AND Long-Acting to require less dosing
teburtaline
lasts 12 hours (MDI)
Peak effect in 2 hours, duration 12 hours
Onset 10-20 minutes - prevent!
11. -pril ACE Inhibitor (Captopril, lisinopril)
Therapeutic Use: HTN, HF, MI, Diabetic Neuropathy
12. -pam, -lam Benzodiazepine/DONT CONFUSE WITH PRAM
13. -statin Antilipidemic (lovastatin, simvastatin)
Therapeutic Use: Hypercholesterolemia, Prevention of Coronary Events, Protection
against MI and stroke in clients with disbetes
14. -asone, -solone Corticosteroid (prednisone, prednisolone)
Therapeutic Use: status asthmaticus, acute asthma attack, asthma attack PPX
, ATI Pharmacology
Study online at https://quizlet.com/_4cte0s
15. -olol Beta Blocker (propranolol, metoprolol)
Therapeutic Use: HTN, Angina, Tachydysrhythmia, HF, MI
16. -cillin Penicillin
17. Dosing Admin- Shake inhaler - attach spacer
istration Tech- Exhale, press canister, inhale
niques (MDI) - Hold breath for 10 seconds (or as long as possible)
Exhale through pursed lips
Wait 1 minute before repeating
Clean and rinse case, cap
18. -ide Oral Hypoglycemic (Biguanides, glipizide)
Therapeutic Use: Used in conjunction of diet and exercise to control blood glucose
levels in type 2 diabetes mellitus
19. -prazole Proton Pump Inhibitor (omeprazole, lansoprazole)
Therapeutic Use: gastric and peptic ulcer, GERD, Zollinger-Ellison syndrome
20. -ase Thrombolytic
21. -mycin Aminoglycoside
22. -tyline Tricyclic Antidepressant (amitriptyline, imipramine, nortriptyline) Trips and IMI
23. -pram, -ine SSRIs (fluoxetine, sertraline, paroxetine, citalopram, escitalopram)PRAM NOT
PAM!!!!
24. Antidote/Rever- Acetylcysteine
sal Agent:
Acetaminophen
ACET for ACET
, ATI Pharmacology
Study online at https://quizlet.com/_4cte0s
25. Antidote/Rever- flumazenil (Romazicon - GABA receptor antagonist)
sal Agent:
Benzodiazepine
If you get a FLU
from benzos
26. VIR Nephrotoxicity - renal dysfunction - administer intravenous slowly over 1 hr;
encourage fluid intake during and after therapy
Causes inflammation or phlebitis at injection sites! - infuse slowly over 1 hour
Wear gloves for topical application
Patient Teaching
Wash area and keep dry
Take as directed
Avoid sexual activity
27. vincristine (On- NO PREGO for CANCER DRUGS
covin) NOT bone marrow toxic!
Peripheral neuropathy effects - report weakness, paresthesia, tingling, ataxia
Alopecia - hair loss will occur after 7-10 days and last 2 months after therapy
stopped
Tissue damage from extravasation - use central line for infusions
Give antiemetic for N/V = Good oral hygiene, avoid mouthwash with alcohol
28. Intravenous (He- Monitor VS, obtain baseline CBC, platelet count, hematocrit levels
parin) continu-
ous drip on a Double check dosages when preparing with another nurse!
pump:
Monitor infusion and bleeding every 30-60 minutes
Monitor aPTT every 4-6 hours until therapeutic range maintained, then daily
aPTT-28-35 but up to 87 on HEP
29. digoxin immune FAB
Study online at https://quizlet.com/_4cte0s
1. Therapeutic 0.8 to 2.0 ng/ml
Drug Levels: Toxic Level: greater than 3.4 ng/ml
Digoxin
2. CLONIDINE Adverse Effects/Nursing Considerations:
Drowsiness/sedation - will improve with time, careful to avoid driving and other
activities
Dry mouth - will improve with time, suck on hard candy
Constipation - drink lots of water
Rebound hypertension - don't stop suddenly (can be given oral, and transdermal)
- wean off over 1-2 weeks
Administer patch on hairless, clean, dry skin and be sure to remove old patch
Other patient teaching - avoid taking with alcohol and other medications that
cause drowsiness!
3. Therapeutic 0.5 to 0.8 ng/ml A 58 year old who doesn't listen
Drug Levels:
Gentamicin
4. sargramostim increases WBC
5. Therapeutic 1.5 to 5.0 mcg/ml
Drug Levels: Toxic Level: greater than 5 mcg/ml
Lidocaine
6. Therapeutic 0.4 to 1.0 mEq/L
Drug Levels: Toxic Level: greater than 1.5 mEq/L
Lithium
7. Therapeutic 4 to 8 mg/dL
Drug Levels: Toxic Level: greater than 9 mg/dL
Magnesium
Sulfate
, ATI Pharmacology
Study online at https://quizlet.com/_4cte0s
8. Therapeutic 10 to 30 mcg/ml
Drug Levels: Toxic Level: greater than 40 mcg/ml
Phenobarbital
9. GENTAMYCIN 58 year old with bad kidneys, who doesn't listen, and can't see because he fell in
a trough and got a rash.
Nephrotoxicity - monitor and report!
Hearing loss (ototoxicity) - ringing in ear, headache, dizziness, vertigo; stop and
notify the physician
Neurologic (numbness, tingling, weakness, optic nerve dysfunction (visual
changes) - monitor and report
Hypersensitivity - report rash, urticaria
Monitor peak and trough
Peak - 30 minutes AFTER administration
Trough - right BEFORE next dose
10. salmeterol AND Long-Acting to require less dosing
teburtaline
lasts 12 hours (MDI)
Peak effect in 2 hours, duration 12 hours
Onset 10-20 minutes - prevent!
11. -pril ACE Inhibitor (Captopril, lisinopril)
Therapeutic Use: HTN, HF, MI, Diabetic Neuropathy
12. -pam, -lam Benzodiazepine/DONT CONFUSE WITH PRAM
13. -statin Antilipidemic (lovastatin, simvastatin)
Therapeutic Use: Hypercholesterolemia, Prevention of Coronary Events, Protection
against MI and stroke in clients with disbetes
14. -asone, -solone Corticosteroid (prednisone, prednisolone)
Therapeutic Use: status asthmaticus, acute asthma attack, asthma attack PPX
, ATI Pharmacology
Study online at https://quizlet.com/_4cte0s
15. -olol Beta Blocker (propranolol, metoprolol)
Therapeutic Use: HTN, Angina, Tachydysrhythmia, HF, MI
16. -cillin Penicillin
17. Dosing Admin- Shake inhaler - attach spacer
istration Tech- Exhale, press canister, inhale
niques (MDI) - Hold breath for 10 seconds (or as long as possible)
Exhale through pursed lips
Wait 1 minute before repeating
Clean and rinse case, cap
18. -ide Oral Hypoglycemic (Biguanides, glipizide)
Therapeutic Use: Used in conjunction of diet and exercise to control blood glucose
levels in type 2 diabetes mellitus
19. -prazole Proton Pump Inhibitor (omeprazole, lansoprazole)
Therapeutic Use: gastric and peptic ulcer, GERD, Zollinger-Ellison syndrome
20. -ase Thrombolytic
21. -mycin Aminoglycoside
22. -tyline Tricyclic Antidepressant (amitriptyline, imipramine, nortriptyline) Trips and IMI
23. -pram, -ine SSRIs (fluoxetine, sertraline, paroxetine, citalopram, escitalopram)PRAM NOT
PAM!!!!
24. Antidote/Rever- Acetylcysteine
sal Agent:
Acetaminophen
ACET for ACET
, ATI Pharmacology
Study online at https://quizlet.com/_4cte0s
25. Antidote/Rever- flumazenil (Romazicon - GABA receptor antagonist)
sal Agent:
Benzodiazepine
If you get a FLU
from benzos
26. VIR Nephrotoxicity - renal dysfunction - administer intravenous slowly over 1 hr;
encourage fluid intake during and after therapy
Causes inflammation or phlebitis at injection sites! - infuse slowly over 1 hour
Wear gloves for topical application
Patient Teaching
Wash area and keep dry
Take as directed
Avoid sexual activity
27. vincristine (On- NO PREGO for CANCER DRUGS
covin) NOT bone marrow toxic!
Peripheral neuropathy effects - report weakness, paresthesia, tingling, ataxia
Alopecia - hair loss will occur after 7-10 days and last 2 months after therapy
stopped
Tissue damage from extravasation - use central line for infusions
Give antiemetic for N/V = Good oral hygiene, avoid mouthwash with alcohol
28. Intravenous (He- Monitor VS, obtain baseline CBC, platelet count, hematocrit levels
parin) continu-
ous drip on a Double check dosages when preparing with another nurse!
pump:
Monitor infusion and bleeding every 30-60 minutes
Monitor aPTT every 4-6 hours until therapeutic range maintained, then daily
aPTT-28-35 but up to 87 on HEP
29. digoxin immune FAB
