Advanced Pharmacology
Final Assessment
(With Solutions)
2025
A nurse is assessing a client who has a new prescription for chlorpromazine to treat
schizophrenia. The client has a mask-like facial expression and is experiencing
involuntary movements and tremors. Which of the following medications should the
nurse anticipate administering?
1, Amantadine. 2, Bupropion
3, Phenelzine 4, Hydroxyzine
A nurse is caring for an older adult client who has a prescription for zolpidem at
bedtime to promote sleep. The nurse should plan to monitor the client for which of the
following adverse effects? 4
1, ecchymosis 2, decrease urine output.
3, increase blood pressure. 4, dizziness
A nurse on a medical unit is preparing to administer alendronate 40 mg PO for an
older adult client who has Paget's disease of the bone. Which of the following actions
should be the nurse's priority?
1, Administer the medication to the client before breakfast in the morning. 2,
Ambulate the client to a chair prior to administering the medication.
3. Give the medication to the client with water rather than milk.
4. Teach the client how to take the medication at home.
A nurse is caring for a client who has a new prescription for ergotamine. The nurse
should recognize that ergotamine is administered to treat which of the following
conditions? 2
1. Raynaud's phenomenon
2. Migraine headaches
3. Ulcerative colitis
4. Anemia
,A nurse is caring for a client who has peptic ulcer disease and reports a
headache. Which of the following medications should the nurse plan to
administer?
1. Ibuprofen
2. Naproxen
3. Aspirin
4. Acetaminophen
A nurse is providing teaching to a parent of a child who has asthma and a new
prescription for a cromolyn sodium metered dose inhaler. Which of the following
statements by the parent indicates the need for further teaching?
1. "I will give my child a dose as soon as wheezing starts."
2. My child should rinse out his mouth after using the inhaler."
3. "My child should exhale completely before placing the inhaler in his mouth."
4. "If my child has difficulty breathing in the dose, a spacer can be used."
A nurse is reviewing laboratory values for a client who reports fatigue and cold
intolerance. The client has an increased thyroid stimulating hormone (TSH) level and
a decreased total T3 and T4 level. The nurse should anticipate a prescription for
which of the following medications?
1. Methimazole
2. Somatropin
3. Levothyroxine
4. Propylthiouracil
A nurse is planning care for a client who has a seizure disorder and a new prescription
for valproic acid. Which of the following laboratory values should the nurse plan to
monitor? (Select all that apply)
1. PTT
2. Asparate aminotransferase (AST)
3. Alanine aminotransferase (ALT)
A nurse is providing teaching to a client who has a new prescription for
hydrochlorothiazide 50 mg PO daily to treat hypertension. Which of the following
instructions should the nurse include in the teaching?
1. "Take hydrochlorothiazide as needed for edema."
2. Check your weight once each week."
3. "Take the hydrochlorothiazide on an empty stomach."
4. "Take the hydrochlorothiazide in the morning."
A 68-year-old patient with a history of heart failure is prescribed digoxin. Which of the
following electrolyte imbalances would MOST significantly increase the risk of digoxin toxicity?
a) Hyperkalemia
b) Hypokalemia
c) Hypercalcemia
, d) Hypomagnesemia
Correct ANS: b) Hypokalemia
Rationale: Hypokalemia increases the binding of digoxin to the Na+/K+-ATPase pump,
leading to increased digoxin effect and potential toxicity.
A patient presents with a severe allergic reaction and is administered epinephrine. Which of
the following receptor subtypes is primarily responsible for the bronchodilatory effects of
epinephrine?
a) Alpha-1
b) Alpha-2
c) Beta-1
d) Beta-2
Correct ANS: d) Beta-2
Rationale: Beta-2 receptors in the bronchial smooth muscle cause bronchodilation when
activated.
A patient is taking warfarin for the prevention of thromboembolic events. The nurse should
monitor which of the following laboratory values to assess the therapeutic effect of warfarin?
a) Activated Partial Thromboplastin Time (aPTT)
b) International Normalized Ratio (INR)
c) Platelet count
d) Bleeding time
Correct ANS: b) International Normalized Ratio (INR)
Rationale: INR is the standard measure used to monitor the effects of warfarin and adjust
the dosage accordingly.
A patient with type 2 diabetes is prescribed metformin. Which of the following is the MOST
common side effect associated with metformin?
a) Hypoglycemia
b) Lactic acidosis
c) Gastrointestinal disturbances
d) Weight gain
Correct ANS: c) Gastrointestinal disturbances
Rationale: Metformin commonly causes gastrointestinal side effects like nausea, diarrhea,
and abdominal discomfort.
A patient is experiencing an acute asthma exacerbation and is receiving albuterol via nebulizer.
Which of the following is the primary mechanism of action of albuterol?
a) Blocks muscarinic receptors
b) Stimulates beta-2 adrenergic receptors
c) Inhibits phosphodiesterase
d) Activates leukotriene receptors
Correct ANS: b) Stimulates beta-2 adrenergic receptors