ALU 301 FINAL EXAM-1 UPDATED ACTUAL Questions and CORRECT
Answers
1. Helper T-Cells Help both other T-lymphocytes and b-lymphocytes become activated and are
critical for immunity
Do not have immunoglobulin antibodies on their membrane surface.
Have receptors that recognize antigen.
2. Neutrophils Are the most abundant white blood cell in the blood.
Circulate in the blood (unlike Macrophages that reside in tissue)
Concentrate at the site of infection.
Release toxic chemicals to eliminate invasive organisms.
3. Primary T-lym- DiGeorge Syndrome is a disease wehere chromosomal defect prevents the de-
phocyte Immun- velopment embryonic cells into a normal sized thymus. With a small Thymus
odeficiency the cells cannot develop normally and their number is reduced Causing cardiac
malformations.
4. Cytotoxic T-Cells are T-lymphocytes that when active by antigen are able to destroy or remove the
infectious microorganism
5. Mediators -Im- Cytokines are cell to cell chemical mediators
mune system Made by the immune system to influence the actions of other cells.
Part of both Innate and adaptive immunity
General function is to regulate the growth, differentiation and enhance the
activation of immune cells.
6. Receptors Cell Membrane molecules that conform to a target on a Microbe or foreign
substance
7. Cytokines Are cell to cell chemical mediators.
Are made by immune cells to influence the actions of other cells.
Are important in both innate and adaptive immunity. Regulate growth and the
differentiation and enhance the activation of immune cells.
8. Natural Killers
, Cells that recognize altered surface molecules as "Foreign" and move to destroy
the cells that carry them
9. IgA Deficiency The absence can result in respiratory infections
Associated with increased risk if systemic lupus
Is relative common in Caucasians
Treatment is essentially symptomatic
10. Monoclonal Has a risk for transformation into multiple myeloma
gammopathy
11. Polyclonal gam- Is a immune system disorder associated with chronic infections
mopathy
12. Low Serum Glob- Can indicate a primary immune deficiency
ulin
13. Remicade Biologic therapy used for treatment of inflammatory bowel disease
14. The presence of Recent infection
the IgM antibody
to an infectious
antigen indicates
what?
15. The differential Appendicitis
diagnosis of in- infectious diarrhea
flammatory bow- celiac spure
el disease in- bowel ischemia
cludes diverticulitis
small bowel lymphoma
irritable bowel syndrome
16. Crohn's Disease
, Granulomatous enteritis, regional enteritis, ileitis or terminal ileitis
Most common symptom is Abdominal pain
Causes inflammation of all layers of the bowel wall
Can involve nearby lymph nodes.
All Parts of gastrointestinal tract can be involved -mouth to anus.
Skip lesions often seen
Affect women more than men
17. Risk regarding The premalignant lesion is usually Not a polyp
cancer with Ul- The duration of disease is a risk factor
cerative colitis A colectomy is recommended when dysplasia is present
18. Statements re- Fistulas are more common in Crohn's disease
garding inflam- The premalignant lesion is not a polyp
matory bowel Toxic megacolon can be life threatening complication
disease Arthritis is the most common extraintestinal manifestation.
19. Ulcerative Colitis Male diagnosed more than females
Little increase in mortality once disease is controlled
More often confined to the left colon
Its onset can be more severe over age 60 than with a younger individual.
Most common symptom is Rectal bleeding
20. Immune system Combat infections
cells Interact by secreting soluble proteins
Originate in the bone marrow
21. Most common Pneumonia
cause of death in
advanced multi-
ple sclerosis
22.
Answers
1. Helper T-Cells Help both other T-lymphocytes and b-lymphocytes become activated and are
critical for immunity
Do not have immunoglobulin antibodies on their membrane surface.
Have receptors that recognize antigen.
2. Neutrophils Are the most abundant white blood cell in the blood.
Circulate in the blood (unlike Macrophages that reside in tissue)
Concentrate at the site of infection.
Release toxic chemicals to eliminate invasive organisms.
3. Primary T-lym- DiGeorge Syndrome is a disease wehere chromosomal defect prevents the de-
phocyte Immun- velopment embryonic cells into a normal sized thymus. With a small Thymus
odeficiency the cells cannot develop normally and their number is reduced Causing cardiac
malformations.
4. Cytotoxic T-Cells are T-lymphocytes that when active by antigen are able to destroy or remove the
infectious microorganism
5. Mediators -Im- Cytokines are cell to cell chemical mediators
mune system Made by the immune system to influence the actions of other cells.
Part of both Innate and adaptive immunity
General function is to regulate the growth, differentiation and enhance the
activation of immune cells.
6. Receptors Cell Membrane molecules that conform to a target on a Microbe or foreign
substance
7. Cytokines Are cell to cell chemical mediators.
Are made by immune cells to influence the actions of other cells.
Are important in both innate and adaptive immunity. Regulate growth and the
differentiation and enhance the activation of immune cells.
8. Natural Killers
, Cells that recognize altered surface molecules as "Foreign" and move to destroy
the cells that carry them
9. IgA Deficiency The absence can result in respiratory infections
Associated with increased risk if systemic lupus
Is relative common in Caucasians
Treatment is essentially symptomatic
10. Monoclonal Has a risk for transformation into multiple myeloma
gammopathy
11. Polyclonal gam- Is a immune system disorder associated with chronic infections
mopathy
12. Low Serum Glob- Can indicate a primary immune deficiency
ulin
13. Remicade Biologic therapy used for treatment of inflammatory bowel disease
14. The presence of Recent infection
the IgM antibody
to an infectious
antigen indicates
what?
15. The differential Appendicitis
diagnosis of in- infectious diarrhea
flammatory bow- celiac spure
el disease in- bowel ischemia
cludes diverticulitis
small bowel lymphoma
irritable bowel syndrome
16. Crohn's Disease
, Granulomatous enteritis, regional enteritis, ileitis or terminal ileitis
Most common symptom is Abdominal pain
Causes inflammation of all layers of the bowel wall
Can involve nearby lymph nodes.
All Parts of gastrointestinal tract can be involved -mouth to anus.
Skip lesions often seen
Affect women more than men
17. Risk regarding The premalignant lesion is usually Not a polyp
cancer with Ul- The duration of disease is a risk factor
cerative colitis A colectomy is recommended when dysplasia is present
18. Statements re- Fistulas are more common in Crohn's disease
garding inflam- The premalignant lesion is not a polyp
matory bowel Toxic megacolon can be life threatening complication
disease Arthritis is the most common extraintestinal manifestation.
19. Ulcerative Colitis Male diagnosed more than females
Little increase in mortality once disease is controlled
More often confined to the left colon
Its onset can be more severe over age 60 than with a younger individual.
Most common symptom is Rectal bleeding
20. Immune system Combat infections
cells Interact by secreting soluble proteins
Originate in the bone marrow
21. Most common Pneumonia
cause of death in
advanced multi-
ple sclerosis
22.
