Infectious Disease Rosh Review UPDATED ACTUAL Questions and
CORRECT Answers
1. 33-year-old woman presents to the ED for a two-day B Cryptococcal meningitis
history of headache, photophobia, and neck stiffness.
Her past medical history is significant for human im-
munodeficiency virus. While interviewing the patient,
she is unable to tell you where she is and appears
confused. A lumbar puncture is performed, and an
india ink stain of the cerebrospinal fluid reveals encap-
sulated yeast. Which of the following is the most likely
diagnosis?
A Coccidioidomycosis
B Cryptococcal meningitis
C Lyme meningitis
D Toxoplasmosis
2. A 75-year-old woman who recently returned from a D West Nile virus infection
visit to Thailand is brought in by her family to the clinic
with progressive muscle weakness, headache, and al-
tered mental status that began about a week after she
returned from her trip. The symptoms were mild ini-
tially and accompanied by a fever, malaise, and some
muscle aches that lasted for about three days before
the other symptoms began. A physical exam reveals a
positive Brudzinski sign, and a computed tomography
scan of her head is negative. Which of the following is
the most likely diagnosis?
A Hemorrhagic stroke
B Myasthenia gravis
C Rocky Mountain spotted fever
D West Nile virus infection
3. A 64-year-old woman who has been admitted for three B Clostridioides diflcile in-
, days for treatment of aspiration pneumonia complains fection
CORRECT Answers
1. 33-year-old woman presents to the ED for a two-day B Cryptococcal meningitis
history of headache, photophobia, and neck stiffness.
Her past medical history is significant for human im-
munodeficiency virus. While interviewing the patient,
she is unable to tell you where she is and appears
confused. A lumbar puncture is performed, and an
india ink stain of the cerebrospinal fluid reveals encap-
sulated yeast. Which of the following is the most likely
diagnosis?
A Coccidioidomycosis
B Cryptococcal meningitis
C Lyme meningitis
D Toxoplasmosis
2. A 75-year-old woman who recently returned from a D West Nile virus infection
visit to Thailand is brought in by her family to the clinic
with progressive muscle weakness, headache, and al-
tered mental status that began about a week after she
returned from her trip. The symptoms were mild ini-
tially and accompanied by a fever, malaise, and some
muscle aches that lasted for about three days before
the other symptoms began. A physical exam reveals a
positive Brudzinski sign, and a computed tomography
scan of her head is negative. Which of the following is
the most likely diagnosis?
A Hemorrhagic stroke
B Myasthenia gravis
C Rocky Mountain spotted fever
D West Nile virus infection
3. A 64-year-old woman who has been admitted for three B Clostridioides diflcile in-
, days for treatment of aspiration pneumonia complains fection
