Physiology, 12th Edition (Hoehn, Haynes, Abbott) – Verified
NCLEX/HESI-Style Questions with Rationales
Chapter/Section: Chapter 1, Section 1.1
An Overview of Anatomy & Physiology
Subtopic: Complementarity of Structure & Function
Cognitive Level: Recall
Difficulty: Easy
Stem: Which statement best describes the principle of
complementarity of structure and function? (≤70 words)
A. Function dictates anatomical form.
B. Structure and function are unrelated.
C. Structure determines function; anatomy constrains
physiology.
D. Physiology is a subset of anatomy.
Correct answer: C
Rationale (correct): Marieb emphasizes that the form of a body
structure determines its function — for example, tooth shape
relates to cutting or grinding (Fig. 1.1). This principle
(complementarity) underlies why anatomical detail predicts
physiological capabilities. Understanding this link aids clinical
assessment (e.g., valve anatomy → unidirectional blood flow).
Pearson
,Why A is wrong: It inverts the relationship — Marieb states
structure constrains function, not the other way round.
Clinically, anatomy must be known to predict function.
Why B is wrong: The text explicitly links structure and function;
they are inseparable.
Why D is wrong: Physiology is not a subset of anatomy; they are
complementary disciplines.
Teaching point: Anatomy (form) constrains and explains
physiology (function). Pearson
A&P002
Chapter: 1 — Section: 1.1 Studying Anatomy; pp. 32–33
Subtopic: Tools for studying anatomy (palpation, auscultation)
Cognitive Level: Application
Difficulty: Medium
Stem: A nurse palpates a swollen lymph node to assess
infection. Which statement best explains why palpation is
useful? (≤70 words)
A. Palpation reveals microscopic tissue structure.
B. Palpation provides functional insight by directly measuring
enzymatic activity.
C. Palpation gives anatomical information (size, texture) that
helps infer underlying physiology.
D. Palpation substitutes for imaging in all cases.
Correct answer: C
,Rationale (correct): Marieb lists palpation and auscultation as
clinical tools for studying anatomy in living persons; tactile
findings (size, firmness) provide anatomical clues that help infer
physiological status (e.g., inflammation). Palpation
complements imaging and lab data when assessing tissues.
Recognizing physical exam findings bridges anatomy and
physiology in care. Pearson
Why A is wrong: Palpation cannot reveal microscopic histology;
it yields gross anatomical information.
Why B is wrong: Palpation does not measure
biochemical/enzymatic activity directly.
Why D is wrong: Palpation complements but does not fully
substitute for imaging when detailed internal views are
required.
Teaching point: Physical exam techniques give anatomical clues
that help infer physiological states. Pearson
A&P003
Chapter: 1 — Section: 1.2 The body’s organization ranges from
atoms to the entire organism; pp. 33–35, Fig. 1.2
Subtopic: Levels of Structural Organization
Cognitive Level: Recall
Difficulty: Easy
Stem: Which correctly lists the hierarchy of structural
organization from simplest to most complex? (≤70 words)
, A. Tissue → Cell → Organ → Molecule → Organ system
B. Atom → Molecule → Organelle → Cell → Tissue → Organ →
Organ system → Organism
C. Cell → Atom → Molecule → Tissue → Organ → Organism
D. Molecule → Atom → Cell → Tissue → Organ
Correct answer: B
Rationale (correct): Marieb presents the hierarchy beginning at
the chemical level (atoms → molecules), then organelles and
cells, tissues, organs, organ systems, and the organism (Fig. 1.2).
This ordered framework organizes study from molecules to
whole-body function and explains systemic integration.
Knowing levels helps link cellular pathology to organ
dysfunction. Pearson
Why A is wrong: The sequence is out of order; molecules and
atoms belong to the chemical level and precede cells and
tissues.
Why C is wrong: It incorrectly places atoms after cells; atoms
are the simplest level.
Why D is wrong: It misorders atoms and molecules and omits
organ system and organism levels.
Teaching point: Learn A → M → organelle → cell → tissue →
organ → system → organism to connect micro to macro.
Pearson