WGU D027 OBJECTIVE ASSESSMENT 2025/2026
QUESTIONS AND ANSWERS
What organ does cystic fibrosis affect? - ANSWER-Affects the pancreas causing secretions into the
lungs
What is Klinefelter syndrome? - ANSWER-An extra X chromosome for males so example XXY causing
female-like qualities
What is Turner Syndrome? - ANSWER-females. missing or deformed x chromosome. right hemisphere
dysfunction, hearing loss, ear infection, language and articulation disorders, visual spatial and
attentional problems
What is beta thalassemia? - ANSWER-a condition in which the synthesis of the beta-globin chains is
decreased or absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? - ANSWER-Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia). Directly toxic
to lymphoid tissues Selective estrogen receptor modulators (SERM) - for hormone receptor positive
and advanced breast cancer. (Tomaxafin - reduces risk and recurrence risk) - ANSWER-Glucocorticoids
What is the normal ejection fraction? - ANSWER-55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved? - ANSWER-Preserved
What are symptoms of left sided heart failure? - ANSWER-Think PULMONARY. JVD, FVO, rails, S3
murmurs. Number one cause of right sided heart failure!
What are symptoms of right sided heart failure? - ANSWER-Think peripheral vascular. Lower
extremity edema, abdominal distension.
What is the gold standard lab test for heart failure? - ANSWER-BNP. Heart failure is a result greater
than 100
What heart disease is worse with exertion? - ANSWER-Ischemic heart disease because the demand
requirements are higher.
What should you assess before giving Digoxin? - ANSWER-Apical pulse
How should Warfarin be started? - ANSWER-Start initial dose at half to monitor the effects
What causes the destruction of alveolar walls? Air goes in but can't get out which leads to
hyperinflation - ANSWER-Emphysema
What causes excess mucus production and smooth muscle hypertrophy? - ANSWER-Bronchitis
What is a chronic inflammatory obstruction of bronchi? - ANSWER-Asthma, Triggers cause mucus to
clog bronchial tubes.
, What causes an overbite and buffalo hump? - ANSWER-Endocrine disorder called acromegaly
(overproduction of growth hormone)
What causes Addison's disease? - ANSWER-Decreased glucocorticoid (due to autoimmune destruction
of adrenal cortex)
What causes Cushing's syndrome? - ANSWER-excess cortisol
What causes Grave's disease? - ANSWER-overproduction of thyroid hormone. HYPERthyroidism.
When should you instruct the patient to take their FIRST dose of antihypertensive? - ANSWER-At night
to avoid orthostatic hypotension. Educate slow position changes and lay down if needed.
What are side effects of ACE inhibitors? - ANSWER-dry cough
angioedema
hyperkalemia
*Contraindicated in pregnancy
Which type of antihypertensive should NOT be given to patients with Asthma? - ANSWER-
Nonselective beta blocker (-lol) because both beta-2 receptors are effected
What is the first choice of calcium channel blocker? - ANSWER-Verapamil
What side effect should you watch for in a patient taking a statin drug? - ANSWER-Muscle pain which
can lead to rhabdomyolysis, kidney failure, and death.
Which diuretic is NOT used in patients with kidney failure and sickle cell disease? - ANSWER-Thiazide
diuretics
What type of drug is spironolactone? - ANSWER-potassium sparing diuretic
Which type of insulin is the most painful during injection? - ANSWER-Lantus (long-acting)
Why test glycosylated hemoglobin (HgbA1c)? - ANSWER-Most reliable assessment of blood sugar over
the past 3 months. The goal is < 6.5%. A poor result is > 9%
What is the normal range for TSH level? - ANSWER-The normal range of TSH levels is 0.4 to 4.0 milli-
international units per liter. If you're already being treated for a thyroid disorder, the normal range is
0.5 to 3.0 milli-international units per liter. A value ABOVE the normal range usually indicates
hypothyroidism.
What lab test would we recommend for thyroid? - ANSWER-Thyroid peroxidase antibodies (TPO)
symptoms of hypothyroidism - ANSWER-Bradycardia; cold intolerance; lethargy; memory loss; dry
skin; brittle dry hair; decreased appetite; weight gain; constipation; increased serum lipids; decreased
libido; erectile dysfunction
What if a newborn has hypothyroidism? - ANSWER-Requires replacement within a few days and last
for 3 years to prevent mental development changes and dwarfism.
What is Hashimoto's disease? - ANSWER-An autoimmune cause of hypothyroid. Symptoms include
weight gain and fatigue.
Symptoms of hyperthyroidism (thyrotoxicosis) - ANSWER-Tachyarrhythmias, anxiety, insomnia, rapid
flow/speech, hot
GRAVES DISEASE
QUESTIONS AND ANSWERS
What organ does cystic fibrosis affect? - ANSWER-Affects the pancreas causing secretions into the
lungs
What is Klinefelter syndrome? - ANSWER-An extra X chromosome for males so example XXY causing
female-like qualities
What is Turner Syndrome? - ANSWER-females. missing or deformed x chromosome. right hemisphere
dysfunction, hearing loss, ear infection, language and articulation disorders, visual spatial and
attentional problems
What is beta thalassemia? - ANSWER-a condition in which the synthesis of the beta-globin chains is
decreased or absent. Causes low hemoglobin.
Which medication is contraindicated in a patient with Beta Thalassemia? - ANSWER-Ferrous Sulfate
What drug is used in combination with other agent to treat lymphoid tissue (leukemia). Directly toxic
to lymphoid tissues Selective estrogen receptor modulators (SERM) - for hormone receptor positive
and advanced breast cancer. (Tomaxafin - reduces risk and recurrence risk) - ANSWER-Glucocorticoids
What is the normal ejection fraction? - ANSWER-55-60%. Less than 50% is BAD
Is an ejection fraction of 50% reduced or preserved? - ANSWER-Preserved
What are symptoms of left sided heart failure? - ANSWER-Think PULMONARY. JVD, FVO, rails, S3
murmurs. Number one cause of right sided heart failure!
What are symptoms of right sided heart failure? - ANSWER-Think peripheral vascular. Lower
extremity edema, abdominal distension.
What is the gold standard lab test for heart failure? - ANSWER-BNP. Heart failure is a result greater
than 100
What heart disease is worse with exertion? - ANSWER-Ischemic heart disease because the demand
requirements are higher.
What should you assess before giving Digoxin? - ANSWER-Apical pulse
How should Warfarin be started? - ANSWER-Start initial dose at half to monitor the effects
What causes the destruction of alveolar walls? Air goes in but can't get out which leads to
hyperinflation - ANSWER-Emphysema
What causes excess mucus production and smooth muscle hypertrophy? - ANSWER-Bronchitis
What is a chronic inflammatory obstruction of bronchi? - ANSWER-Asthma, Triggers cause mucus to
clog bronchial tubes.
, What causes an overbite and buffalo hump? - ANSWER-Endocrine disorder called acromegaly
(overproduction of growth hormone)
What causes Addison's disease? - ANSWER-Decreased glucocorticoid (due to autoimmune destruction
of adrenal cortex)
What causes Cushing's syndrome? - ANSWER-excess cortisol
What causes Grave's disease? - ANSWER-overproduction of thyroid hormone. HYPERthyroidism.
When should you instruct the patient to take their FIRST dose of antihypertensive? - ANSWER-At night
to avoid orthostatic hypotension. Educate slow position changes and lay down if needed.
What are side effects of ACE inhibitors? - ANSWER-dry cough
angioedema
hyperkalemia
*Contraindicated in pregnancy
Which type of antihypertensive should NOT be given to patients with Asthma? - ANSWER-
Nonselective beta blocker (-lol) because both beta-2 receptors are effected
What is the first choice of calcium channel blocker? - ANSWER-Verapamil
What side effect should you watch for in a patient taking a statin drug? - ANSWER-Muscle pain which
can lead to rhabdomyolysis, kidney failure, and death.
Which diuretic is NOT used in patients with kidney failure and sickle cell disease? - ANSWER-Thiazide
diuretics
What type of drug is spironolactone? - ANSWER-potassium sparing diuretic
Which type of insulin is the most painful during injection? - ANSWER-Lantus (long-acting)
Why test glycosylated hemoglobin (HgbA1c)? - ANSWER-Most reliable assessment of blood sugar over
the past 3 months. The goal is < 6.5%. A poor result is > 9%
What is the normal range for TSH level? - ANSWER-The normal range of TSH levels is 0.4 to 4.0 milli-
international units per liter. If you're already being treated for a thyroid disorder, the normal range is
0.5 to 3.0 milli-international units per liter. A value ABOVE the normal range usually indicates
hypothyroidism.
What lab test would we recommend for thyroid? - ANSWER-Thyroid peroxidase antibodies (TPO)
symptoms of hypothyroidism - ANSWER-Bradycardia; cold intolerance; lethargy; memory loss; dry
skin; brittle dry hair; decreased appetite; weight gain; constipation; increased serum lipids; decreased
libido; erectile dysfunction
What if a newborn has hypothyroidism? - ANSWER-Requires replacement within a few days and last
for 3 years to prevent mental development changes and dwarfism.
What is Hashimoto's disease? - ANSWER-An autoimmune cause of hypothyroid. Symptoms include
weight gain and fatigue.
Symptoms of hyperthyroidism (thyrotoxicosis) - ANSWER-Tachyarrhythmias, anxiety, insomnia, rapid
flow/speech, hot
GRAVES DISEASE
