RBC membrane UPDATED ACTUAL
Exam Questions and CORRECT Answers
RBC membrane - CORRECT ANSWER -like any biologic ( animal cell ) membrane
lipid bilayer - CORRECT ANSWER -hydrophilic polar heads face aqueous plasma
hydrophobic nonpolar acyl tails - CORRECT ANSWER -arranged to form a central part
hidden from the plasma
phospholipids ( PPL ) - CORRECT ANSWER -provide a dynamic fluidity to the
membrane
membrane - CORRECT ANSWER -extreme differences in osmotic pressure , cation
concentrations , and gas concentrations between external plasma and the cytoplasm
membrane - CORRECT ANSWER -provides a semi - permeable barrier
membrane - CORRECT ANSWER -maintaining an osmotic differential
composition - CORRECT ANSWER -58 % proteins , 40 % lipids and 8 % carbohydrates
lipids - CORRECT ANSWER -composed of equal parts of phospholipids and cholesterol
Cholesterol - CORRECT ANSWER -esterified and largely hydrophobic resides parallel to
the acyl tails of the PPL
Cholesterol - CORRECT ANSWER -confers tensile strength to the lipid bilayer
, cholesterol concentration rises - CORRECT ANSWER -the membrane gains strength but
loses elasticity
RBC stretch - CORRECT ANSWER -undamaged up to 2.5X using their resting diameter
Deformability - CORRECT ANSWER -depends on : RBC geometry ( shape ) , viscosity (
its Hb content ) and elasticity
more Hb is present - CORRECT ANSWER -the more viscous and thus there is easy
hemolysis
ratio of cholesterol to PPL - CORRECT ANSWER -remain constant
Membrane enzymes - CORRECT ANSWER -maintain the cholesterol concentration by
regularly exchanging membrane and plasma cholesterol
PPL - CORRECT ANSWER -not equally distributed
Phosphatidylcholine and sphingomyelin - CORRECT ANSWER -predominate in the
OUTER layer
phosphatidylserine ( PS ) and phosphatidylethanolamine - CORRECT ANSWER -form
most of the INNER layer
Distribution of the PPL - CORRECT ANSWER -energy - dependent
Splenic macrophages - CORRECT ANSWER -possess receptors that bind to the PS
Exam Questions and CORRECT Answers
RBC membrane - CORRECT ANSWER -like any biologic ( animal cell ) membrane
lipid bilayer - CORRECT ANSWER -hydrophilic polar heads face aqueous plasma
hydrophobic nonpolar acyl tails - CORRECT ANSWER -arranged to form a central part
hidden from the plasma
phospholipids ( PPL ) - CORRECT ANSWER -provide a dynamic fluidity to the
membrane
membrane - CORRECT ANSWER -extreme differences in osmotic pressure , cation
concentrations , and gas concentrations between external plasma and the cytoplasm
membrane - CORRECT ANSWER -provides a semi - permeable barrier
membrane - CORRECT ANSWER -maintaining an osmotic differential
composition - CORRECT ANSWER -58 % proteins , 40 % lipids and 8 % carbohydrates
lipids - CORRECT ANSWER -composed of equal parts of phospholipids and cholesterol
Cholesterol - CORRECT ANSWER -esterified and largely hydrophobic resides parallel to
the acyl tails of the PPL
Cholesterol - CORRECT ANSWER -confers tensile strength to the lipid bilayer
, cholesterol concentration rises - CORRECT ANSWER -the membrane gains strength but
loses elasticity
RBC stretch - CORRECT ANSWER -undamaged up to 2.5X using their resting diameter
Deformability - CORRECT ANSWER -depends on : RBC geometry ( shape ) , viscosity (
its Hb content ) and elasticity
more Hb is present - CORRECT ANSWER -the more viscous and thus there is easy
hemolysis
ratio of cholesterol to PPL - CORRECT ANSWER -remain constant
Membrane enzymes - CORRECT ANSWER -maintain the cholesterol concentration by
regularly exchanging membrane and plasma cholesterol
PPL - CORRECT ANSWER -not equally distributed
Phosphatidylcholine and sphingomyelin - CORRECT ANSWER -predominate in the
OUTER layer
phosphatidylserine ( PS ) and phosphatidylethanolamine - CORRECT ANSWER -form
most of the INNER layer
Distribution of the PPL - CORRECT ANSWER -energy - dependent
Splenic macrophages - CORRECT ANSWER -possess receptors that bind to the PS
