Nr546 Week 2: Test Your Knowledge Quiz

NR 546 Final PRACTICE EXAM Psychopharmac
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NR546 WEEK 2: TEST YOUR KNOWLEDGE QUIZ

Pharmacokineticsvc-vcanswer--
thevcstudyvcofvcwhatvchappensvctovcavcdrugvcfromvcthevctimevcofvcadministrationvcuntilvcthevcparentvcdrugvcandvcallvcmetabo
esvcleavevcthevcbody

Pharmacokineticsvcconceptsvc-vcanswer--absorption
distribution
metabolism
excretion

FlockhartvcTablevc-vcanswer--drugvcinteractionsvcthatvcarevcmediatedvcbyvccytochromevcP450vcenzymes

comprehensivevclistvcofvcdrugsvcandvcthevcinteractionsvcrelatedvctovcthevccytochromevcP450vcsystem

clientvcfactorsvcthatvcimpactvcthevceffectvcofvcpsychotropicvcmedicationsvc-vcanswer---age
-diet
-smokingvcstatus
-othervcprescribedvcmedications
-over-the-countervcmedications

*allvcimpactvcdrugvcmetabolism

Neurotransmittersvc-vcanswer--
chemicalsvcreleasedvcbyvcneuronsvctovcsendvccommunicationvcacrossvcsynapticvccleftsvctovcothervcneurons
-impactvchumanvcemotionvcandvcbehavior

Manyvcpsychiatricvcdisordersvcandvcclientvcsymptomsvcoccurvcfromvcanvcexcess,vcdeficiency,vcorvcimbalancevcofvc______
__vc-vcanswer--neurotransmitters

Neurotransmission:vc-vcanswer--
thevcchemicalvctransmissionvcofvcinformationvcbetweenvcneuronsvcandvctheirvctargetvccells
-
thevcchemicals,vcorvcneurotransmitters,vcarevcreleasedvcfromvctheirvctransportvcvesiclesvctovcbindvcwithvcreceptorvcsitesvct
performvctheirvcduties,vcwhichvcarevcexcitatoryvcorvcinhibitory
-
neurotransmittervcthenvceithervcreturnedvcandvcstoredvcforvcfuturevcusevc(reuptake)vcorvcinactivatedvcandvcdissolvedvcbyv
zymes

Excitatoryvcneurotransmitters:vc-vcanswer--increasevcthevclikelihoodvcthatvcthevcneuronvcwillvcfirevcanvcactionvcpotential

inhibitoryvcneurotransmitters:vc-vcanswer--decreasevcthevclikelihoodvcthatvcavcneuronvcwillvcfirevcanvcaction

neurotransmittersvcthatvcmostvcimpactvcmentalvchealthvccanvcbevcclassifiedvcintovcfourvcmajorvccategories:vc-vcanswer--
cholinergics
-acetylcholine

1vc/vc5

, NR 546 Final PRACTICE EXAM Psychopharmac
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monoamines
-norepinephrine,vcdopamine,vcserotonin,vchistamine

aminovcacids
-gamma-vcamino-butyricvcacidvcandvcglutamate

neuropeptides

Inhibitors:vcVISAvcCKGQvc-vcanswer--Valproate
Isoniazid
Sulfonamides
Amiodarone
Chloramphenicol
Ketoconazole
GrapefruitvcJuice
Quinidine

-decreasevcmedicationvcmetabolism

Inducers:vcCRAPvcGPSvc-vcanswer--Carbamazepine
Rifampin
Alcohol
Phenytoin
Griseofulvin
Phenobarbital
Sulfonylureas

-increasevcmedicationvcmetabolism

neurotransmittersvcthatvcmayvcbevcresponsiblevcforvcavcclient'svcsymptomsvcofvcdepressionvc-vcanswer--
Imbalancedvclevelsvcofvcacetylcholine,vcnorepinephrine,vcserotonin,vchistamine,vcorvcglutamatevccanvccontributevctovcsy
ptomsvcofvcdepression

clientvcwhovcisvcavcpoorvcmetabolizer:vc-vcanswer--
hasvcavclowervcconcentrationvcofvcthevcnecessaryvcenzymevctovcmetabolizevcavcdrug,vcwhichvcresultsvcinvchighervcbloodvcc
centrationsvcofvcthevcdrug.vc
-increasevcthevcriskvcofvcsidevceffectsvcandvcadversevcreactions

Whyvcisvctrazodonevcnotvcusedvcasvcavcfront-linevcantidepressantvc-vcanswer--
Itsvcantidepressantvcthatvchasvcavcsecondaryvceffectvcofvcblockingvchistaminevcandvcadrenergicvcreceptors
-causesvcsedationvcandvcsomnolencevcandvcasvcavcresult
*oftenvcusedvcasvcanvcadjunctvcinvctherapyvcwhenvcavcdepressedvcpatientvchasvcdifficultyvcsleeping

effectvconvcneurotransmittersvcandvcsidevceffects:vcSelectivevcSerotoninvcReuptakevcInhibitorsvc(SSRIs)vc-vcanswer--
Inhibitsvcthevcreuptakevcofvcserotonin,vcwhichvccanvccausevcnausea,vcagitation,vcheadache,vcandvcsexualvcdysfunction

effectvconvcneurotransmittersvcandvcsidevceffects:vcSerotoninvcandvcNorepinephrinevcReuptakevcInhibitorsvc(SNRIs)vc-
vcanswer--

Inhibitsvcthevcreuptakevcofvcserotoninvcandvcnorepinephrine,vcwhichvccanvccausevcnausea,vcsweating,vcinsomnia,vctremo
,vcsexualvcdysfunction

2vc/vc5