QUIZ 1 PHARMACOLOGY 5334 EXAM BRAND NEW ACTUAL EXAM WITH ANSWERS.

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QUIZ 1 PHARMACOLOGY 5334 EXAM
BRAND NEW ACTUAL EXAM WITH
ANSWERS.

Gout short term therapy - correct answer --less than 3 x a yr
-NSAIDs: 1st line
-Glucocorticoids: 2nd line or if not working w/ NSAIDs




Gout (long term treatment) - correct answer --more than 3 x year
-uricosuric dx




Colchicine - correct answer --tx, reduces, and aborts attack
-no longer 1st line dx




Allopurinol - correct answer -1st line dx for tx for chronic
topaceous gout




Pegloticase - correct answer -IV tx for pt not responded to oral tx;
last resort

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Serotonin 1B/1D MOA - correct answer -Binds to intracranial
receptor> vasoconstricts (tx: migraine)




Serotonin treatment - correct answer -aborts ongoing migraine




serotonin drug interactions - correct answer -Ergot,
sumpatriptans, other triptans > vasoconstriction




Treximet - correct answer -Sumatriptan + Naproxen




Cluster headache treatment - correct answer --glucocorticoids
- verapamil
-lithium




Carbamazepine BBW - correct answer -test for HLA-B 1502 in
Asians; causes SJS and TEN

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Narrow Therapeutic Index Drugs - correct answer -■Warfarin
sodium (Coumadin): monitor INR.


■ Digoxin (Lanoxin): monitor digoxin level, EKG, electrolytes
(potassium, magnesium, calcium).


■ Theophylline: monitor blood levels.


■ Carbamezapine (Tegretol) and phenytoin (Dilantin): monitor
blood levels.


■ Levothyroxine: monitor TSH.


■ Lithium: monitor blood levels, TSH (risk of HYPOthyroidism).




P450 inducers - correct answer -Drugs that increase rate of dx
metabolism




P450 substrates - correct answer --Dx metabolized by 450 liver
enzymes