NAGELHOUT PHARM 2 Test 2 Actual Exam
With 100% Verified Questions and Correct
Solutions Excellent Scores
Bicarb and CO2 similarity? Difference? - CORRECT-ANSWER-Both make
anesthetics work faster
Bicarb makes outside more alkaline.
CO2 makes inside more acidic
Bupivicaine special because? - CORRECT-ANSWER-preferentially binds
to cardiac proteins = CARDIOTOXICITY
S/S of LAST - CORRECT-ANSWER-1. Excitement (agitation, auditory
changes, metallic taste, confusion, tinnitus, numbness,
lightheadedness, visual changes, muscle twitching)
2. Seizures, Depression (drowsiness, coma, or respiratory arrest) and
Early Cardiotoxic symptoms (HTN, Tachy, arrythmias)
3. Cardiac Arrest
,Treatment of LAST? - CORRECT-ANSWER-1. Establish Airway (Intubate
High risk pt and use least invasive airway on healthy pt.)
2. Stop seizure (Benzo/Lipid emulsion)
3. ACLS if necessary (W/O LIDOCAINE)
PDE for cGMP? Which nervous system? - CORRECT-ANSWER-1, 5, & 6;
Parasympathetic
PDE for cAMP? Which nervous system? - CORRECT-ANSWER-3, 4, & 7;
Sympathetic
Non-Selective PDE - CORRECT-ANSWER-2
Milrinone MOA; Receptors? - CORRECT-ANSWER-Inhibits
phosphodiesterase, allows for less cAMP and cGMP to be broken down.
short synapse - CORRECT-ANSWER-sympathetic nervous system
, pre synaptic - CORRECT-ANSWER-lytic
post synaptic - CORRECT-ANSWER-mimetic
autoreceptor - CORRECT-ANSWER-influences further release of
catecholamine
Cycloplegia - CORRECT-ANSWER-loss of accommodation for distance
Explain allergies to Local Anesthetics - CORRECT-ANSWER-1. Most
commonly found with esters (bc people are exposed to the lipophilic
portion PABA daily via cosmetics).
2. When allergic to an ester you're allergic to all esters but not to
amides
3. When allergic to an amide youre ONLY allergic to that amide
MOA of Locals - CORRECT-ANSWER-blocking Na channels in nerves
With 100% Verified Questions and Correct
Solutions Excellent Scores
Bicarb and CO2 similarity? Difference? - CORRECT-ANSWER-Both make
anesthetics work faster
Bicarb makes outside more alkaline.
CO2 makes inside more acidic
Bupivicaine special because? - CORRECT-ANSWER-preferentially binds
to cardiac proteins = CARDIOTOXICITY
S/S of LAST - CORRECT-ANSWER-1. Excitement (agitation, auditory
changes, metallic taste, confusion, tinnitus, numbness,
lightheadedness, visual changes, muscle twitching)
2. Seizures, Depression (drowsiness, coma, or respiratory arrest) and
Early Cardiotoxic symptoms (HTN, Tachy, arrythmias)
3. Cardiac Arrest
,Treatment of LAST? - CORRECT-ANSWER-1. Establish Airway (Intubate
High risk pt and use least invasive airway on healthy pt.)
2. Stop seizure (Benzo/Lipid emulsion)
3. ACLS if necessary (W/O LIDOCAINE)
PDE for cGMP? Which nervous system? - CORRECT-ANSWER-1, 5, & 6;
Parasympathetic
PDE for cAMP? Which nervous system? - CORRECT-ANSWER-3, 4, & 7;
Sympathetic
Non-Selective PDE - CORRECT-ANSWER-2
Milrinone MOA; Receptors? - CORRECT-ANSWER-Inhibits
phosphodiesterase, allows for less cAMP and cGMP to be broken down.
short synapse - CORRECT-ANSWER-sympathetic nervous system
, pre synaptic - CORRECT-ANSWER-lytic
post synaptic - CORRECT-ANSWER-mimetic
autoreceptor - CORRECT-ANSWER-influences further release of
catecholamine
Cycloplegia - CORRECT-ANSWER-loss of accommodation for distance
Explain allergies to Local Anesthetics - CORRECT-ANSWER-1. Most
commonly found with esters (bc people are exposed to the lipophilic
portion PABA daily via cosmetics).
2. When allergic to an ester you're allergic to all esters but not to
amides
3. When allergic to an amide youre ONLY allergic to that amide
MOA of Locals - CORRECT-ANSWER-blocking Na channels in nerves
