Nurs 6630 Psychopharmacology Midterm Exam Questions With Correct Verified Answers | 100% Pass (A+ Certified)

1. Serotonin regulates Answer Mood, emotion, feeding, and reproductive behavior 2. This class of antidepressants binds to presynaptic SERT and inhibits them from reuptake of serotonin to increase levels in the synaptic cleft to bind with postsysnaptic 5HT2 receptors Answer SSRIs 3. First line therapy for MDD due to milder side effect profiles Answer SSRIs 4. Six Common SSRIs Answer citalopram, escitalopram, fluoxetine, fluvoxamine, sertraline, paroxetine 5. Onset of therapeutic benefit from SSRIs Answer 4-6 weeks 6. In addition to MDD, SSRIs also treat 2 / 30 Answer Chronic Anxiety, PTSD, OCD, and eating disorders (bulimia) 7. Five Common side effects of SSRIs include Answer Anxiety, insomnia, GI distress, sexual dysfunction (ED), SIADH 8. Severe side effect of SSRIs in children/adolescents under age 25 years old Answer suicidal ideation 9. Life threatening adverse effect of SSRIs, especially when used in combination with other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.) Answer Serotonin Syndrome 10. Excess accumulation of serotonin resulting in overstimulation of the nervous system Answer Serotonin Syndrome 11. Seven symptoms of Serotonin Syndrome Answer Flushing, hyperthermia, agitation, muscle rigidity, seizure, coma, HYPERreflexia 12. The treatment for serotonin syndrome 3 / 30 Answer Cyproheptadine (5-HT2 receptor antagonist) 13. Cyproheptadine treats serotonin syndrome by Answer blocking 5-HT2 receptors (serotonin antagonist) 14. When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal include Answer Irritability, headaches, and insomnia 15. Medicine specific side effect of citalopram Answer Prolonged QT interval (normal=0.4.-0.44 seconds) 16. This SSRI is pregnancy category D due to associations with congenital heart defects Answer Paroxetine 17.