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, Chapterb1:bPrinciplesbofbPharmacology
MultiplebChoice
1. refer(s)btobspecificbmolecularbchangesbthatboccurbwhenbabdrugbbind
sbtobabparticularbtargetbsiteborbreceptor,bwhile
arebthebresultingbwidespreadbalterationsbinbfunction.
a. Drugbaction;btherapeuticbeffects
b. Sidebeffects;bdrugbeffects
c. Therapeuticbeffects;bsidebeffects
d. Drugbaction;bdrugbeffects
ANSWER:bd
TextbookbReference:bPharmacology:bThebSciencebofbDrugbAction
2. Afterbdrugbadministrationbhasboccurred,bthebamountbofbdrugbinbthebbloodbtha
tbisbfreebtobbindbatbspecificbtargetbsitesbisbreferredbtobas
a. thebtherapeuticbdose.
b. first-passbeffects.
c. bioavailability.
d. ED50.
ANSWER:bc
TextbookbReference:bPharmacokineticbFactorsbDeterminingbDrugbAction
3. Thebspecificbmolecularbchangesbthatboccurbwhenbabdrugbbindsbtobabparticular
btargetbsiteborbreceptorbarebreferredbtobas
a. drugbeffects.
b. drugbaction.
c. sidebeffects.
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, d. placebobeffects.
ANSWER:bb
TextbookbReference:bPharmacology:bThebSciencebofbDrugbAction
4. Whichbofbthebfollowingbisbnotbabpossiblebexplanationbforbplacebobeffects?
a. Pavlovianbconditioning
b. Geneticbvariation
c. Drugbcompetition
d. Expectationbofboutcome
ANSWER:bc
TextbookbReference:bPharmacology:bThebSciencebofbDrugbAction
5. The
administrationbofboxytocinbhasbbeenbproposedbasbabtreatmentbforbautis
m.
a. intravenous
b. oral
c. intranasal
d. intracerebral
ANSWER:bc
TextbookbReference:bPharmacokineticbFactorsbDeterminingbDrugbAction
6. Whichbfactorbdoesbnotbaffectbthebpharmacokineticsbofbabdrug?
a. Routebofbadministration
b. Lipidbsolubility
c. Depotbbinding
d. Drugbaction
ANSWER:bd
TextbookbReference:bPharmacokineticbFactorsbDeterminingbDrugbAction
7. First-passbmetabolismboccursbwhenbdrugsbarebtaken
a. orally.
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, Chapterb1:bPrinciplesbofbPharmacology
MultiplebChoice
1. refer(s)btobspecificbmolecularbchangesbthatboccurbwhenbabdrugbbind
sbtobabparticularbtargetbsiteborbreceptor,bwhile
arebthebresultingbwidespreadbalterationsbinbfunction.
a. Drugbaction;btherapeuticbeffects
b. Sidebeffects;bdrugbeffects
c. Therapeuticbeffects;bsidebeffects
d. Drugbaction;bdrugbeffects
ANSWER:bd
TextbookbReference:bPharmacology:bThebSciencebofbDrugbAction
2. Afterbdrugbadministrationbhasboccurred,bthebamountbofbdrugbinbthebbloodbtha
tbisbfreebtobbindbatbspecificbtargetbsitesbisbreferredbtobas
a. thebtherapeuticbdose.
b. first-passbeffects.
c. bioavailability.
d. ED50.
ANSWER:bc
TextbookbReference:bPharmacokineticbFactorsbDeterminingbDrugbAction
3. Thebspecificbmolecularbchangesbthatboccurbwhenbabdrugbbindsbtobabparticular
btargetbsiteborbreceptorbarebreferredbtobas
a. drugbeffects.
b. drugbaction.
c. sidebeffects.
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, d. placebobeffects.
ANSWER:bb
TextbookbReference:bPharmacology:bThebSciencebofbDrugbAction
4. Whichbofbthebfollowingbisbnotbabpossiblebexplanationbforbplacebobeffects?
a. Pavlovianbconditioning
b. Geneticbvariation
c. Drugbcompetition
d. Expectationbofboutcome
ANSWER:bc
TextbookbReference:bPharmacology:bThebSciencebofbDrugbAction
5. The
administrationbofboxytocinbhasbbeenbproposedbasbabtreatmentbforbautis
m.
a. intravenous
b. oral
c. intranasal
d. intracerebral
ANSWER:bc
TextbookbReference:bPharmacokineticbFactorsbDeterminingbDrugbAction
6. Whichbfactorbdoesbnotbaffectbthebpharmacokineticsbofbabdrug?
a. Routebofbadministration
b. Lipidbsolubility
c. Depotbbinding
d. Drugbaction
ANSWER:bd
TextbookbReference:bPharmacokineticbFactorsbDeterminingbDrugbAction
7. First-passbmetabolismboccursbwhenbdrugsbarebtaken
a. orally.
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