Chapter 51 Immunizing Drugs and Pandemic Preparedness
Sealock Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. Two patients arrive at the clinic a young boy with sickle-cell anemia and a 57-year-old woman with
early-stage Hodgkin’s disease.
Both patients require the same vaccine. What vaccine do they require?
a. Bacillus Calmette-Guérin (BCG) vaccine b. Tetanus, diphtheria, and pertussis vaccine c. Hepatitis
B virus vaccine, inactivated
d. Haemophilus influenzae type b conjugate vaccine
ANS D
H. influenzae type b conjugate vaccine is usually given to patients with sickle-cell anemia
(an immunodeficiency syndrome) and with Hodgkin’s disease.
DIF Cognitive Level Analysis
2. Which type of immunity occurs when the body is exposed to a relatively harmless form of an
antigen that imprints this information on the body’s memory bank and stimulates the body’s defences
to resist any subsequent exposures?
a. Active immunity
b. Attenuating immunity
c. Naturally acquired passive immunity
d. Artificially acquired passive
immunity
ANS A
Active immunity causes an antigen–antibody response and stimulates the body’s defences to resist
any subsequent exposures.
DIF Cognitive Level Knowledge
, 3. A 45-year-old male has had a series of equine-derived immunizing drugs in preparation for a trip
to an undeveloped country. His wife brings him to the emergency department because he has
developed edema of the face, tongue, and throat and is having trouble breathing. What is he
experiencing?
a. Serum sickness
b. Cross-sensitivity
c. An adverse
effect
d. An anaphylactic
reaction
ANS A
Serum sickness sometimes occurs after repeated injections of equine-derived immunizing agents and
is characterized by edema of the face, tongue, and throat; rash; urticaria; fever; flushing; dyspnea; and
other conditions.
DIF Cognitive Level Application
4. A 12-month-old infant has received measles, mumps, and rubella virus (MMR) vaccine. Her mother
calls the clinic to ask how she can help her infant to “feel better.” What is the nurse’s best suggestion
to the mother?
a. Apply an ice pack to the injection site.
b. Give the infant pediatric Aspirin for the
pain. c. Apply warm compresses to the
injection site.
d. Observe the site for further swelling and redness.
ANS C
Applying warm compresses to the injection site and using acetaminophen (not Aspirin, which carries
the risk of Reye’s syndrome) should help to relieve the infant’s discomfort. Contraindications to the
administration of immunizing agents include active infections, pregnancy, febrile illnesses, and a history
Sealock Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. Two patients arrive at the clinic a young boy with sickle-cell anemia and a 57-year-old woman with
early-stage Hodgkin’s disease.
Both patients require the same vaccine. What vaccine do they require?
a. Bacillus Calmette-Guérin (BCG) vaccine b. Tetanus, diphtheria, and pertussis vaccine c. Hepatitis
B virus vaccine, inactivated
d. Haemophilus influenzae type b conjugate vaccine
ANS D
H. influenzae type b conjugate vaccine is usually given to patients with sickle-cell anemia
(an immunodeficiency syndrome) and with Hodgkin’s disease.
DIF Cognitive Level Analysis
2. Which type of immunity occurs when the body is exposed to a relatively harmless form of an
antigen that imprints this information on the body’s memory bank and stimulates the body’s defences
to resist any subsequent exposures?
a. Active immunity
b. Attenuating immunity
c. Naturally acquired passive immunity
d. Artificially acquired passive
immunity
ANS A
Active immunity causes an antigen–antibody response and stimulates the body’s defences to resist
any subsequent exposures.
DIF Cognitive Level Knowledge
, 3. A 45-year-old male has had a series of equine-derived immunizing drugs in preparation for a trip
to an undeveloped country. His wife brings him to the emergency department because he has
developed edema of the face, tongue, and throat and is having trouble breathing. What is he
experiencing?
a. Serum sickness
b. Cross-sensitivity
c. An adverse
effect
d. An anaphylactic
reaction
ANS A
Serum sickness sometimes occurs after repeated injections of equine-derived immunizing agents and
is characterized by edema of the face, tongue, and throat; rash; urticaria; fever; flushing; dyspnea; and
other conditions.
DIF Cognitive Level Application
4. A 12-month-old infant has received measles, mumps, and rubella virus (MMR) vaccine. Her mother
calls the clinic to ask how she can help her infant to “feel better.” What is the nurse’s best suggestion
to the mother?
a. Apply an ice pack to the injection site.
b. Give the infant pediatric Aspirin for the
pain. c. Apply warm compresses to the
injection site.
d. Observe the site for further swelling and redness.
ANS C
Applying warm compresses to the injection site and using acetaminophen (not Aspirin, which carries
the risk of Reye’s syndrome) should help to relieve the infant’s discomfort. Contraindications to the
administration of immunizing agents include active infections, pregnancy, febrile illnesses, and a history
