Chapter 49 Anti-inflammatory and Antigout Drugs
Sealock Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. Which types of effects are possible therapeutic effects of nonsteroidal anti-inflammatory drugs
(NSAIDs)?
a. Anxiolytic effects b.
Diuretic effects
c. Antipyretic effects
d. Antimicrobial effects
ANS C
NSAIDs have antipyretic effects but not the other effects listed. DIF
Cognitive Level Knowledge
2. A 75-year-old female patient has been given naproxen sodium (Aleve®) for the treatment of
rheumatoid arthritis. Which type of medication will have a possible interaction with this NSAID? a.
Antibiotics
b. Decongestants c. Anticoagulants d. Antihistamines
ANS C
Anticoagulants taken with NSAIDs may cause increased bleeding tendencies because of platelet
inhibition and hypoprothrombinemia.
DIF Cognitive Level Comprehension
3. An older adult patient tells the nurse that he uses acetylsalicylic acid for “anything that ails me.”
What are the most common signs of chronic salicylate intoxication in adults?
a. Photosensitivity and nervousness b.
Tinnitus and hearing loss
c. Acute gastrointestinal bleeding and anorexia
d. Hyperventilation and central nervous system (CNS) effects
, ANS B
The most frequent manifestations of chronic intoxication in adults are tinnitus and hearing loss.
Hyperventilation and CNS effects are manifestations of chronic intoxication in children.
DIF Cognitive Level Comprehension
4. A patient is being treated with allopurinol (Zyloprim®) for gout. Which therapeutic result should the
nurse monitor for?
a. Decreased uric acid levels
b. Adequate prothrombin time
c. Increased white blood cell count
d. Increased hemoglobin and hematocrit levels
ANS A
Treatment of gout with allopurinol should result in a decrease in uric acid levels.
DIF Cognitive Level Application
5. A patient is prescribed colchicine for the treatment of gout. What important information should the
nurse give the patient about this drug?
a. Fluids should be restricted while on colchicine therapy.
b. Colchicine should be taken with meals.
c. The drug should be discontinued when symptoms are reduced.
d. Report to the health care provider the occurrence of increased pain, blood in the urine, or
excessive fatigue.
ANS D
Colchicine may cause renal effects; therefore, these symptoms must be reported immediately.
Colchicine should be taken on an empty stomach for better absorption, and fluids should be increased
unless contraindicated. Patients should not discontinue the drug on their own; they should seek advice
from the physician regarding discontinuation of the medication.
DIF Cognitive Level Analysis
Sealock Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. Which types of effects are possible therapeutic effects of nonsteroidal anti-inflammatory drugs
(NSAIDs)?
a. Anxiolytic effects b.
Diuretic effects
c. Antipyretic effects
d. Antimicrobial effects
ANS C
NSAIDs have antipyretic effects but not the other effects listed. DIF
Cognitive Level Knowledge
2. A 75-year-old female patient has been given naproxen sodium (Aleve®) for the treatment of
rheumatoid arthritis. Which type of medication will have a possible interaction with this NSAID? a.
Antibiotics
b. Decongestants c. Anticoagulants d. Antihistamines
ANS C
Anticoagulants taken with NSAIDs may cause increased bleeding tendencies because of platelet
inhibition and hypoprothrombinemia.
DIF Cognitive Level Comprehension
3. An older adult patient tells the nurse that he uses acetylsalicylic acid for “anything that ails me.”
What are the most common signs of chronic salicylate intoxication in adults?
a. Photosensitivity and nervousness b.
Tinnitus and hearing loss
c. Acute gastrointestinal bleeding and anorexia
d. Hyperventilation and central nervous system (CNS) effects
, ANS B
The most frequent manifestations of chronic intoxication in adults are tinnitus and hearing loss.
Hyperventilation and CNS effects are manifestations of chronic intoxication in children.
DIF Cognitive Level Comprehension
4. A patient is being treated with allopurinol (Zyloprim®) for gout. Which therapeutic result should the
nurse monitor for?
a. Decreased uric acid levels
b. Adequate prothrombin time
c. Increased white blood cell count
d. Increased hemoglobin and hematocrit levels
ANS A
Treatment of gout with allopurinol should result in a decrease in uric acid levels.
DIF Cognitive Level Application
5. A patient is prescribed colchicine for the treatment of gout. What important information should the
nurse give the patient about this drug?
a. Fluids should be restricted while on colchicine therapy.
b. Colchicine should be taken with meals.
c. The drug should be discontinued when symptoms are reduced.
d. Report to the health care provider the occurrence of increased pain, blood in the urine, or
excessive fatigue.
ANS D
Colchicine may cause renal effects; therefore, these symptoms must be reported immediately.
Colchicine should be taken on an empty stomach for better absorption, and fluids should be increased
unless contraindicated. Patients should not discontinue the drug on their own; they should seek advice
from the physician regarding discontinuation of the medication.
DIF Cognitive Level Analysis
