Chapter 43 Antibiotics Part 1 Sulfonamides, Penicillins, Cephalosporins, Macrolides, and Tetracyclines
Sealock Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. Patients who are allergic to penicillin may also be hypersensitive to which drugs?
a. Tetracyclines b.
Sulfonamides
c. Cephalosporins
d. Imipenem-cilastatin
ANS C
Allergy to penicillin may also result in hypersensitivity to cephalosporins.
DIF Cognitive Level Comprehension
2. A patient has been prescribed a tetracycline. What important information should the nurse tell the
patient about taking this medication?
a. Acidic foods, such as citrus fruit juices, help to enhance absorption.
b. Milk and cheese products result in decreased levels of tetracycline.
c. Antacids taken with the medication help to reduce gastrointestinal distress.
d. The medication should be taken with high-fibre foods to prevent constipation.
ANS B
Milk and cheese products result in decreased levels of tetracycline when taken with the medication.
Antacids also interfere with absorption and should not be taken with tetracycline.
DIF Cognitive Level Comprehension
3. Which drug may result in an interaction if taken with penicillin?
a. Antacids
b. acetaminophen (Tylenol®)
, c. digoxin (Lanoxin®)
d. Nonsteroidal anti-inflammatory drugs (NSAIDs)
ANS D
Drug interactions may occur when both penicillin and NSAIDs are taken.
DIF Cognitive Level Application
4. A patient taking an antibiotic suddenly develops hives. The hives are an example of which reactions?
a. A desired reaction
b. An allergic reaction
c. An idiosyncratic reaction
d. An unpredictable reaction
ANS B
Hives are an allergic reaction known to occur in some patients receiving antibiotics.
DIF Cognitive Level Comprehension
5. A patient is admitted with a fever of 39 C of unknown origin. The assessment reveals bilateral
crackles and a productive cough.
The physician has ordered sputum and blood cultures and the administration of ampicillin 500 mg
intravenous stat and then every 6 hours. Which is the correct sequence for the nurse to follow to
complete these orders?
a. Blood culture, ampicillin dose, sputum culture b. Sputum culture, ampicillin dose, blood culture c.
Ampicillin dose, blood and sputum cultures
d. Blood and sputum cultures, ampicillin dose
ANS D
Blood and sputum culture specimens should be obtained before initiating drug therapy; otherwise, the
presence of antibiotics in the tissues may result in misleading culture results.
Sealock Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. Patients who are allergic to penicillin may also be hypersensitive to which drugs?
a. Tetracyclines b.
Sulfonamides
c. Cephalosporins
d. Imipenem-cilastatin
ANS C
Allergy to penicillin may also result in hypersensitivity to cephalosporins.
DIF Cognitive Level Comprehension
2. A patient has been prescribed a tetracycline. What important information should the nurse tell the
patient about taking this medication?
a. Acidic foods, such as citrus fruit juices, help to enhance absorption.
b. Milk and cheese products result in decreased levels of tetracycline.
c. Antacids taken with the medication help to reduce gastrointestinal distress.
d. The medication should be taken with high-fibre foods to prevent constipation.
ANS B
Milk and cheese products result in decreased levels of tetracycline when taken with the medication.
Antacids also interfere with absorption and should not be taken with tetracycline.
DIF Cognitive Level Comprehension
3. Which drug may result in an interaction if taken with penicillin?
a. Antacids
b. acetaminophen (Tylenol®)
, c. digoxin (Lanoxin®)
d. Nonsteroidal anti-inflammatory drugs (NSAIDs)
ANS D
Drug interactions may occur when both penicillin and NSAIDs are taken.
DIF Cognitive Level Application
4. A patient taking an antibiotic suddenly develops hives. The hives are an example of which reactions?
a. A desired reaction
b. An allergic reaction
c. An idiosyncratic reaction
d. An unpredictable reaction
ANS B
Hives are an allergic reaction known to occur in some patients receiving antibiotics.
DIF Cognitive Level Comprehension
5. A patient is admitted with a fever of 39 C of unknown origin. The assessment reveals bilateral
crackles and a productive cough.
The physician has ordered sputum and blood cultures and the administration of ampicillin 500 mg
intravenous stat and then every 6 hours. Which is the correct sequence for the nurse to follow to
complete these orders?
a. Blood culture, ampicillin dose, sputum culture b. Sputum culture, ampicillin dose, blood culture c.
Ampicillin dose, blood and sputum cultures
d. Blood and sputum cultures, ampicillin dose
ANS D
Blood and sputum culture specimens should be obtained before initiating drug therapy; otherwise, the
presence of antibiotics in the tissues may result in misleading culture results.
